Association of the neuron-specific RNA binding domain-containing protein ELAV with the coiled body inDrosophila neurons

Conserved Structures and Diversity of Functions of RNA-Binding Proteins

1994 • 1,873 citations

Messenger RNA degradation in eukaryotes

1993 • 858 citations

Shuttling of pre-mRNA binding proteins between nucleus and cytoplasm

1992 • 825 citations

A novel macromolecular structure is a target of the promyelocyte-retinoic acid receptor oncoprotein

1994 • 798 citations

A novel nuclear structure containing the survival of motor neurons protein.

1996 • 759 citations

RNA-binding proteins as developmental regulators.

1989 • 679 citations

Retinoic acid regulates aberrant nuclear localization of PML-RARα in acute promyelocytic leukemia cells

1994 • 668 citations

Analysis of the RNA-recognition motif and RS and RGG domains: conservation in metazoan pre-mRNA splicing factors

1993 • 663 citations

Macromolecular Domains within the Cell Nucleus

1993 • 611 citations

A common RNA recognition motif identified within a defined U1 RNA binding domain of the 70K U1 snRNP protein

1989 • 601 citations

HuD, a paraneoplastic encephalomyelitis antigen, contains RNA-binding domains and is homologous to Elav and sex-lethal

1991 • 553 citations

A factor, U2AF, is required for U2 snRNP binding and splicing complex assembly

1988 • 535 citations

Associations between distinct pre-mRNA splicing components and the cell nucleus.

1991 • 523 citations

The t(15;17) translocation alters a nuclear body in a retinoic acid-reversible fashion.

1994 • 492 citations

Characterization and spatial distribution of the ELAV protein during Drosophila melanogaster development

1991 • 491 citations

Transcription-dependent colocalization of the U1, U2, U4/U6, and U5 snRNPs in coiled bodies

1992 • 402 citations

Identification, purification, and biochemical characterization of U2 small nuclear ribonucleoprotein auxiliary factor.

1989 • 375 citations

The poly(A)-poly(A)-binding protein complex is a major determinant of mRNA stability in vitro.

1989 • 373 citations

The structure of mammalian small nuclear ribonucleoproteins. Identification of multiple protein components reactive with anti-(U1)ribonucleoprotein and anti-Sm autoantibodies.

1984 • 371 citations

Human autoantibody to a novel protein of the nuclear coiled body: immunological characterization and cDNA cloning of p80-coilin.

1991 • 369 citations

Hel-N1: an autoimmune RNA-binding protein with specificity for 3' uridylate-rich untranslated regions of growth factor mRNAs.

1993 • 356 citations

A Three-Dimensional View of Precursor Messenger RNA Metabolism Within the Mammalian Nucleus

1993 • 335 citations

Immunological and ultrastructural studies of the nuclear coiled body with autoimmune antibodies

1991 • 327 citations

A conserved family of elav-like genes in vertebrates.

1995 • 309 citations

Ultrastructural distribution of nuclear ribonucleoproteins as visualized by immunocytochemistry on thin sections.

1984 • 306 citations

Identification of a novel nuclear domain.

1991 • 285 citations

Isolation and characterization of cDNA encoding a human nuclear antigen predominantly recognized by autoantibodies from patients with primary biliary cirrhosis.

1990 • 266 citations

A monoclonal antibody recognizing nuclear matrix-associated nuclear bodies

1992 • 258 citations

Mammalian nuclei contain foci which are highly enriched in components of the pre-mRNA splicing machinery.

1991 • 243 citations

Assembly of snRNP-containing coiled bodies is regulated in interphase and mitosis--evidence that the coiled body is a kinetic nuclear structure.

1993 • 214 citations

Mutant Alleles at the Locus elav in Drosophila melanogaster lead to Nervous System Defects. A Developmental-Genetic Analysis

1985 • 203 citations

Cloning and intracellular localization of the U2 small nuclear ribonucleoprotein auxiliary factor small subunit.

1992 • 203 citations

Immunocytochemical analysis of the coiled body in the cell cycle and during cell proliferation.

1993 • 201 citations

Anti-RNP monoclonal antibodies derived from a mouse strain with lupus-like autoimmunity.

1982 • 192 citations

Mammalian homologs of Drosophila ELAV localized to a neuronal subset can bind in vitro to the 3' UTR of mRNA encoding the Id transcriptional repressor

1994 • 168 citations

In vivo detection of snRNP-rich organelles in the nuclei of mammalian cells.

1991 • 167 citations

Gene elav of Drosophila melanogaster: A prototype for neuronal‐specific RNA binding protein gene family that is conserved in flies and humans

1993 • 166 citations

Nucleoplasmic organization of small nuclear ribonucleoproteins in cultured human cells.

1993 • 162 citations

Is the sphere organelle/coiled body a universal nuclear component?

1995 • 150 citations

U1 and U2 small nuclear RNAs are present in nuclear speckles.

1992 • 141 citations

Intranuclear localization of snRNP antigens.

1986 • 140 citations

Differential interaction of splicing snRNPs with coiled bodies and interchromatin granules during mitosis and assembly of daughter cell nuclei.

1994 • 135 citations

Hel-N1/Hel-N2 proteins are bound to poly(A)+ mRNA in granular RNP structures and are implicated in neuronal differentiation

1996 • 122 citations

The Poly(A)-Poly(A)-Binding Protein Complex Is a Major Determinant of mRNA Stability In Vitro

1989 • 122 citations

Paraneoplastic Encephalomyelitis Antigens Bind to the AU-rich Elements of mRNA

1995 • 120 citations

Differences in snRNP localization between transformed and nontransformed cells.

1992 • 119 citations

The organization of spliceosomal components in the nuclei of higher plants

1995 • 115 citations

Nuclear organization of pre-mRNA processing

1993 • 111 citations

Hel-N1: an Autoimmune RNA-Binding Protein with Specificity for 3' Uridylate-Rich Untranslated Regions of Growth Factor mRNAs

1993 • 108 citations

Identification and characterization of a sphere organelle protein

1993 • 108 citations

A sequence compilation and comparison of exons that are alternatively spliced in neurons

1994 • 105 citations

The RNA 3′ cleavage factors CstF 64 kDa and CPSF 100 kDa are concentrated in nuclear domains closely associated with coiled bodies and newly synthesized RNA.

1996 • 103 citations

U7 small nuclear RNA in C snurposomes of the Xenopus germinal vesicle.

1993 • 98 citations

The Drosophila gene rbp9 encodes a protein that is a member of a conserved group of putative RNA binding proteins that are nervous system-specific in both flies and humans

1993 • 90 citations

Molecular analysis of the coiled body

1995 • 89 citations

The sphere organelle contains small nuclear ribonucleoproteins.

1989 • 86 citations

Distribution of snRNPs, splicing factor SC-35 and actin in interphase nuclei: immunocytochemical evidence for differential distribution during changes in functional states

1993 • 82 citations

Ultrastructural distribution of ribonucleoprotein complexes during mitosis. snRNP antigens are contained in mitotic granule clusters.

1989 • 60 citations

Lampbrush loop-specific protein of Drosophila hydei.

1984 • 57 citations

Human p80-coilin is targeted to sphere organelles in the amphibian germinal vesicle.

1994 • 55 citations

Nuclear organization of splicing snRNPs during differentiation of murine erythroleukemia cells in vitro.

1993 • 53 citations

Structure, expression and chromosomal localization of human p80-coilin gene

1994 • 49 citations

The small nuclear RNAs of Drosophila

1984 • 48 citations

Spheres, coiled bodies and nuclear bodies

1995 • 36 citations

Small nuclear ribonucleoprotein complexes of Drosophila melanogaster.

1982 • 33 citations

Hel-N2: a novel isoform of Hel-N1 which is conserved in rat neural tissue and produced in early embryogenesis

1994 • 28 citations

Polypeptide components ofDrosophilasmall nuclear ribonucleoprotein particles

1991 • 28 citations

Isolation and embryonic expression of Xel-1, a nervous system-specific Xenopus gene related to the elav gene family

1995 • 18 citations

Alteration by heat shock and immunological characterization of Drosophila small nuclear ribonucleoproteins.

1989 • 10 citations

Comparison of the drosophila melanogaster, human and murine sm b cDNAs: evolutionary conservation

1993 • 9 citations