Induction of cytochrome(s) P₄₅₀‐dependent drug metabolism in cultured MH₁C₁ hepatoma cells

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

The Carbon Monoxide-binding Pigment of Liver Microsomes

1964 • 11,832 citations

Human Hepatocellular Carcinoma Cell Lines Secrete the Major Plasma Proteins and Hepatitis B Surface Antigen

1980 • 2,034 citations

Substrate-inducible Microsomal Aryl Hydroxylase in Mammalian Cell Culture

1968 • 1,691 citations

Carcinogenesis: Fundamental Mechanisms and Environmental Effects

1980 • 231 citations

PCB isomers and congeners: Induction of aryl hydrocarbon hydroxylase and ethoxyresorufin O-deethylase enzyme activities in rat hepatoma cells

1982 • 184 citations

Drug metabolism and effects of carcinogens in cultured hepatic cells.

1979 • 171 citations

ESTABLISHMENT OF A CLONAL STRAIN OF HEPATOMA CELLS WHICH SECRETE ALBUMIN

1969 • 137 citations

Studies on fatty liver with isolated hepatocytes

1979 • 126 citations

Limitations of Metabolic Activation Systems Used with in Vitro Tests for Carcinogens

1980 • 106 citations

Metyrapone interaction with hepatic microsomal cytochrome P-450 from rats treated with phenobarbital

1969 • 98 citations

Activation of xenobiotics by monooxygenases: cultures of mammalian cells as analytical tool

1977 • 85 citations

A sensitive radiometric assay of aminopyrine N-demethylation.

1973 • 75 citations

The effect of hepatocyte culture conditions on cytochrome p-450 linked drug metabolising enzymes

1982 • 65 citations

Evaluation of a human hepatoma cell line as a target cell in genetic toxicology

1983 • 61 citations

Presence of cytochrome P-450- and cytochrome P-448-dependent monooxygenase functions in hepatoma cell lines

1980 • 54 citations

Evidence that ligand formation is a mechanism underlying the maintenance of cytochrome P-450 in rat liver cell culture. Potent maintenance by metyrapone

1980 • 48 citations

Multiple differentiated functions in an unusual clonal strain of hepatoma cells

1970 • 44 citations

Long term maintenance and induction of cytochrome P-450 in rat liver cell culture

1982 • 43 citations

Aryl hydrocarbon hydroxylase induction in mammalian liver-derived cell cultures

1976 • 39 citations

Photoperiod-Induced Change in Responsiveness of the Hypothalamic-Pituitary Axis to Exogenous 5<i>α</i>-Dihydrotestosterone and 17<i>β</i>-Estradiol in Castrated Male Hamsters

1980 • 31 citations

Hydroxylation, sulfation, and conjugation of bile acids in rat hepatoma and hepatocyte cultures under the influence of glucocorticoids.

1980 • 29 citations

Sister-chromatid exchange induction by polycyclic aromatic hydrocarbons in an intact cell system of adult rat-liver epithelial cells

1981 • 27 citations

Monooxygenase and UDP-glucuronyltransferase activities in established cell cultures

1980 • 26 citations

Geno- and cytotoxicity of nitrosamines, aflatoxin B₁, and benzo[a]-pyrene in continuous cultures of rat hepatoma cells

1982 • 25 citations

Metabolic activation of benzo[a]pyrene, aflatoxin B1, and dimethylnitrosamine by a human hepatoma cell line

1982 • 24 citations

Sister-chromatid exchange induction by carcinogens in HTC cells An in vitro system which does not require addition of activating factors

1980 • 23 citations

Sister-chromatid exchange induction by indirect mutagens/carcinogens, aryl hydrocarbon hydroxylase activity and benzo[a]pyrene metabolism in cultured human hepatoma cells

1983 • 22 citations

Induction of sister-chromatid exchanges in a rat-liver cell line with chemical carcinogens

1981 • 21 citations

The substituted pyridines metyrapone and nicotinamide are inducers of 5-aminolevulinate synthase and cytochrome P-450 in hepatocyte culture

1982 • 15 citations

Utilization of an established rat hepatoma cell line for mutation studies

1982 • 6 citations