Integrin β1 is required for the invasive behaviour but not proliferation of squamous cell carcinoma cells in vivo

Integrins

2002 • 8,127 citations

A System for Stable Expression of Short Interfering RNAs in Mammalian Cells

2002 • 4,334 citations

Integrin Signaling

1999 • 3,705 citations

RNA interference

2002 • 3,369 citations

Reversion of the Malignant Phenotype of Human Breast Cells in Three-Dimensional Culture and In Vivo by Integrin Blocking Antibodies

1997 • 1,444 citations

Signal transduction through the fibronectin receptor induces collagenase and stromelysin gene expression.

1989 • 1,073 citations

MAP kinase kinase kinase, MAP kinase kinase and MAP kinase

1994 • 1,005 citations

NEW EMBO MEMBER'S REVIEW: Role of integrins in regulating epidermal adhesion, growth and differentiation

2002 • 616 citations

Integrins and cell proliferation

2001 • 509 citations

NEW EMBO MEMBER'S REVIEW: The integrin-actin connection, an eternal love affair

2003 • 480 citations

Surgical-pathologic variables predictive of local recurrence in squamous cell carcinoma of the vulva

1990 • 400 citations

Induced Focal Adhesion Kinase (FAK) Expression in FAK-Null Cells Enhances Cell Spreading and Migration Requiring Both Auto- and Activation Loop Phosphorylation Sites and Inhibits Adhesion-Dependent Tyrosine Phosphorylation of Pyk2

1999 • 395 citations

ERK-MAPK signaling coordinately regulates activity of Rac1 and RhoA for tumor cell motility

2003 • 389 citations

Conditional Ablation of β1 Integrin in Skin

2000 • 376 citations

Focal adhesion kinase signaling activities and their implications in the control of cell survival and motility

2003 • 366 citations

Collective cell movement in primary melanoma explants: plasticity of cell-cell interaction, beta1-integrin function, and migration strategies.

2002 • 314 citations

Suprabasal integrin expression in the epidermis of transgenic mice results in developmental defects and a phenotype resembling psoriasis

1995 • 303 citations

Activated Conformations of Very Late Activation Integrins Detected by a Group of Antibodies (HUTS) Specific for a Novel Regulatory Region(355-425) of the Common β1 Chain

1996 • 298 citations

Integrin regulation of growth factor receptors

2002 • 295 citations

Monoclonal Antibody 9EG7 Defines a Novel β1 Integrin Epitope Induced by Soluble Ligand and Manganese, but Inhibited by Calcium

1995 • 281 citations

A monoclonal antibody against an activation epitope on mouse integrin chain beta 1 blocks adhesion of lymphocytes to the endothelial integrin alpha 6 beta 1.

1993 • 270 citations

A crucial role of β1 integrins for keratinocyte migration in vitro and during cutaneous wound repair

2002 • 266 citations

Signaling via β1 integrins and mitogen-activated protein kinase determines human epidermal stem cell fate in vitro

1999 • 246 citations

α5β1 Integrin Controls Cyclin D1 Expression by Sustaining Mitogen-activated Protein Kinase Activity in Growth Factor-treated Cells

1999 • 218 citations

Integrin expression during human epidermal development in vivo and in vitro

1991 • 203 citations

β1 Integrin Is Essential for Teratoma Growth and Angiogenesis

1997 • 185 citations

Actin cytoskeleton organization in response to integrin-mediated adhesion

1999 • 159 citations

New aspects of integrin signaling in cancer

2000 • 147 citations

Integrin expression in normal, hyperplastic, dysplastic, and malignant oral epithelium

1993 • 145 citations

Involvement of the Small GTPase Rho in Integrin-mediated Activation of Mitogen-activated Protein Kinase

1996 • 137 citations

Dual phosphorylation and autophosphorylation in mitogen-activated protein (MAP) kinase activation

1993 • 118 citations

Fos-transformation activates genes associated with invasion.

1994 • 117 citations

Alpha v integrin inhibitors and cancer therapy.

2003 • 109 citations

Differential Effects of CD18, CD29, and CD49 Integrin Subunit Inhibition on Neutrophil Migration in Pulmonary Inflammation

2001 • 108 citations

A tumor-associated β1 integrin mutation that abrogates epithelial differentiation control

2003 • 74 citations

Increase in suprabasilar integrin adhesion molecule expression in human epidermal neoplasms accompanies increased proliferation occurring with immortalization and tumor progression.

1995 • 66 citations

Targeted disruption of the beta1 integrin gene in a lymphoma cell line greatly reduces metastatic capacity.

1998 • 41 citations

β1 integrin promotes but is not essential for metastasis of ras-myc transformed fibroblasts

1999 • 28 citations

Expression and Cellular Distribution of αvIntegrins inβ1 Integrin-deficient Embryonic Stem Cell-derived Cardiac Cells

2001 • 22 citations

Integrin expression in squamous neoplasia of the cervix

1994 • 21 citations

Integrin expression and function in HPV 16-immortalised human keratinocytes in the presence or absence of v-Ha-ras. Comparison with cervical intraepithelial neoplasia.

1994 • 18 citations

Tumor Angiogenesis in Vulvar Squamous Cell Carcinoma

1999 • 6 citations

Distribution of integrins and extracellular matrix proteins in vulvar squamous cell carcinomas.

1995 • 3 citations

Deleted Work

1955 • 0 citations