Receptor and Nonreceptor-Mediated Organ-Specific Toxicity of Di(2-ethylhexyl)phthalate (DEHP) in Peroxisome Proliferator-Activated Receptorα-Null Mice

Fatty acids and eicosanoids regulate gene expression through direct interactions with peroxisome proliferator-activated receptors α and γ

1997 • 2,105 citations

Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator-activated receptors α and δ

1997 • 2,100 citations

Targeted Disruption of the α Isoform of the Peroxisome Proliferator-Activated Receptor Gene in Mice Results in Abolishment of the Pleiotropic Effects of Peroxisome Proliferators

1995 • 1,626 citations

Differential expression and activation of a family of murine peroxisome proliferator-activated receptors.

1994 • 1,410 citations

The PPARα–leukotriene B4 pathway to inflammation control

1996 • 1,328 citations

The peroxisome proliferator activated receptors (PPARs) and their effects on lipid metabolism and adipocyte differentiation

1996 • 1,036 citations

The mouse peroxisome proliferator activated receptor recognizes a response element in the 5′ flanking sequence of the rat acyl CoA oxidase gene.

1992 • 903 citations

Carcinogenesis by Hepatic Peroxisome Proliferators: Evaluation of the Risk of Hypolipidemic Drugs and Industrial Plasticizers to Humans

1983 • 890 citations

The peroxisome proliferator-activated receptor regulates mitochondrial fatty acid oxidative enzyme gene expression.

1994 • 558 citations

cDNA cloning, chromosomal mapping, and functional characterization of the human peroxisome proliferator activated receptor

1993 • 523 citations

Hepatocarcinogenic Potential of Di(2-Ethylhexyl)phthalate in Rodents and its Implications on Human Risk

1996 • 309 citations

Peroxisome proliferation due to di(2-ethylhexyl) phthalate (DEHP): species differences and possible mechanisms.

1986 • 178 citations

PPAR: a mediator of peroxisome proliferator action

1995 • 174 citations

The peroxisome proliferator activated receptor regulates malic enzyme gene expression.

1994 • 157 citations

Identification of Two mPPAR Related Receptors and Evidence for the Existence of Five Subfamily Members

1993 • 154 citations

Peroxisome proliferator-activated receptor alpha required for gene induction by dehydroepiandrosterone-3 beta-sulfate.

1996 • 139 citations

Peroxisomes: Biology and Importance in Toxicology and Medicine

2007 • 125 citations

Tumor-initiating and promoting activities of di(2-ethylhexyl) phthalate in vivo and in vitro.

1986 • 110 citations

Peroxisome Proliferator‐Activated Receptors and Lipid Metabolism^a

1993 • 87 citations

Regulation of Gene Expression by Fatty Acids and Fibric Acid Derivatives: An Integrative Role for Peroxisome Prolif erator Activated Receptors

1992 • 76 citations

Structure of the Mouse Peroxisome Proliferator Activated Receptor α Gene

1994 • 68 citations

Phthalate Esters, Cystic Kidney Disease in Animals and Possible Effects on Human Health: A Review

1990 • 29 citations

Differential effects of dehydroepiandrosterone (DHEA) on murine lymphopoiesis and myelopoiesis.

1991 • 23 citations