TRA-1A regulates transcription of fog-3, which controls germ cell fate in C. elegans

THE GENETICS OF CAENORHABDITIS ELEGANS

1974 • 14,589 citations

Genome sequence of the nematode C-elegans: A platform for investigating biology

1998 • 3,265 citations

Efficient gene transfer in C.elegans: extrachromosomal maintenance and integration of transforming sequences.

1991 • 3,108 citations

Genetic control of programmed cell death in the nematode C. elegans

1986 • 1,790 citations

Evidence for evolutionary conservation of sex-determining genes

1998 • 769 citations

NONDISJUNCTION MUTANTS OF THE NEMATODE CAENORHABDITIS ELEGANS

1979 • 768 citations

PCR primer: a laboratory manual.

2003 • 743 citations

EGG-LAYING DEFECTIVE MUTANTS OF THE NEMATODE CAENORHABDITIS ELEGANS

1983 • 730 citations

A binding site for Gli proteins is essential for HNF-3β floor plate enhancer activity in transgenics and can respond to Shh in vitro

1997 • 667 citations

The C. elegans Protein EGL-1 Is Required for Programmed Cell Death and Interacts with the Bcl-2–like Protein CED-9

1998 • 628 citations

A uniform genetic nomenclature for the nematode Caenorhabditis elegans

1979 • 382 citations

Transcriptional activation of hedgehog target genes in Drosophila is mediated directly by the cubitus interruptus protein, a member of the GLI family of zinc finger DNA-binding proteins.

1996 • 380 citations

A sensitive method for the determination of protein-DNA binding specificities

1990 • 346 citations

MUTATIONS CAUSING TRANSFORMATION OF SEXUAL PHENOTYPE IN THE NEMATODE CAENORHABDITIS ELEGANS

1977 • 253 citations

Gain-of-Function Mutations of fem-3, a Sex-Determination Gene in Caenorhabditis elegans

1987 • 236 citations

mab-3, a gene required for sex-specific yolk protein expression and a male-specific lineage in C. elegans

1988 • 235 citations

Molecular analysis of the C. elegans sex-determining gene tra-1: A gene encoding two zinc finger proteins

1992 • 233 citations

The TRA-1A Sex Determination Protein of C. elegans Regulates Sexually Dimorphic Cell Deaths by Repressing the egl-1 Cell Death Activator Gene

1999 • 227 citations

A sex-determining gene, fem-1, required for both male and hermaphrodite development in Caenorhabditis elegans

1984 • 216 citations

SEX DETERMINATION IN THE NEMATODE C. ELEGANS: ANALYSIS OF tra-3 SUPPRESSORS AND CHARACTERIZATION OF fem GENES

1986 • 210 citations

Zinc Fingers in Caenorhabditis elegans : Finding Families and Probing Pathways

1998 • 200 citations

A genetic analysis of the sex-determining gene, tra-1, in the nematode Caenorhabditis elegans.

1987 • 196 citations

POLYPLOIDS AND SEX DETERMINATION IN CAENORHABDITIS ELEGANS

1979 • 194 citations

The product of fem-1, a nematode sex-determining gene, contains a motif found in cell cycle control proteins and receptors for cell-cell interactions

1990 • 176 citations

fog-1, a regulatory gene required for specification of spermatogenesis in the germ line of Caenorhabditis elegans.

1990 • 173 citations

Intersex, a temperature-sensitive mutant of the nematode Caenorhabditis elegans

1978 • 151 citations

Similarity of DNA binding and transcriptional regulation by Caenorhabditis elegans MAB-3 and Drosophila melanogaster DSX suggests conservation of sex determining mechanisms

1999 • 141 citations

Development of the male reproductive system and sexual transformation in the nematode Caenorhabditis elegans

1976 • 139 citations

Centromeres Take Flight: Alpha Satellite and the Quest for the Human Centromere

1998 • 135 citations

The fog-3 gene and regulation of cell fate in the germ line of Caenorhabditis elegans.

1995 • 132 citations

Specification of male development in Caenorhabditis elegans: The fem genes

1984 • 131 citations

Hedgehog signaling regulates transcription through cubitus interruptus, a sequence-specific DNA binding protein

1997 • 115 citations

Cloning of a yolk protein gene family from Caenorhabditis elegans

1984 • 108 citations

The Caenorhabditis elegans sex determining gene fem-3 is regulated post-transcriptionally.

1992 • 96 citations

Sex-lethal, master and slave: a hierarchy of germ-line sex determination in Drosophila

1993 • 95 citations

Analysis of the role of tra-1 in germline sex determination in the nematode Caenorhabditis elegans.

1989 • 94 citations

Sex determination in the germ line of Drosophila depends on genetic signals and inductive somatic factors*

1989 • 92 citations

CELL LINEAGE AND FATE DETERMINATION

1999 • 90 citations

Zinc fingers in sex determination: only one of the twoC.elegansTra-1 proteins binds DNAin Vitro

1993 • 86 citations

Caenorhabditis elegans sex-determining protein FEM-2 is a protein phosphatase that promotes male development and interacts directly with FEM-3.

1996 • 80 citations

The C. elegans sex-determining gene fem-2 encodes a putative protein phosphatase.

1995 • 78 citations

A Novel Member of the Tob Family of Proteins Controls Sexual Fate in Caenorhabditis elegans Germ Cells

2000 • 77 citations

Interstitial cell migration in Hydra attenuata

1984 • 50 citations

Sex Determination and X Chromosome Dosage Compensation

1997 • 49 citations

Potential regulatory elements of nematode vitellogenin genes revealed by interspecies sequence comparison

1989 • 48 citations

SL1 trans-splicing specified by AU-rich synthetic RNA inserted at the 5' end of Caenorhabditis elegans pre-mRNA.

1995 • 43 citations

Sxl in the germline of Drosophila: A target for somatic late induction

1994 • 34 citations

Molecular cloning and duplication of the nematode sex-determining gene tra-1.

1993 • 31 citations