The product of fem-1, a nematode sex-determining gene, contains a motif found in cell cycle control proteins and receptors for cell-cell interactions

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

Improved M13 phage cloning vectors and host strains: nucleotide sequences of the M13mpl8 and pUC19 vectors

1985 • 15,222 citations

Improved tools for biological sequence comparison.

1988 • 11,455 citations

[1] Production of single-stranded plasmid DNA

1987 • 2,642 citations

Nucleotide sequence from the neurogenic locus Notch implies a gene product that shares homology with proteins containing EGF-like repeats

1985 • 1,063 citations

Gene required in G1 for commitment to cell cycle and in G2 for control of mitosis in fission yeast

1981 • 740 citations

Toward a physical map of the genome of the nematode Caenorhabditis elegans

1986 • 631 citations

Sex in flies: the splice of life

1989 • 468 citations

Genome linking with yeast artificial chromosomes

1988 • 438 citations

Sequence of the notch locus of Drosophila melanogaster: relationship of the encoded protein to mammalian clotting and growth factors.

1986 • 427 citations

Integrative transformation of Caenorhabditis elegans

1986 • 417 citations

Cell cycle control of the yeast HO gene: Cis- and Trans-acting regulators

1987 • 392 citations

fog-2, a germ-line-specific sex determination gene required for hermaphrodite spermatogenesis in Caenorhabditis elegans.

1988 • 368 citations

Similarity between cell-cycle genes of budding yeast and fission yeast and the Notch gene of Drosophila

1987 • 366 citations

glp-1 and lin-12, genes implicated in distinct cell-cell interactions in C. elegans, encode similar transmembrane proteins

1989 • 345 citations

[7] Random cloning and sequencing by the M13/dideoxynucleotide chain termination method

1987 • 292 citations

The Caenorhabditis elegans lin-12 gene encodes a transmembrane protein with overall similarity to Drosophila Notch

1988 • 281 citations

Evidence for a transposon in caenorhabditis elegans

1983 • 257 citations

MUTATIONS CAUSING TRANSFORMATION OF SEXUAL PHENOTYPE IN THE NEMATODE CAENORHABDITIS ELEGANS

1977 • 253 citations

Gain-of-Function Mutations of fem-3, a Sex-Determination Gene in Caenorhabditis elegans

1987 • 236 citations

Cloning, sequencing and transcriptional control of the Schizosaccharomyces pombe cdc10 ‘start’ gene.

1985 • 228 citations

A sex-determining gene, fem-1, required for both male and hermaphrodite development in Caenorhabditis elegans

1984 • 216 citations

SEX DETERMINATION IN THE NEMATODE C. ELEGANS: ANALYSIS OF tra-3 SUPPRESSORS AND CHARACTERIZATION OF fem GENES

1986 • 210 citations

A genetic analysis of the sex-determining gene, tra-1, in the nematode Caenorhabditis elegans.

1987 • 196 citations

POLYPLOIDS AND SEX DETERMINATION IN CAENORHABDITIS ELEGANS

1979 • 194 citations

xol-1: A gene that controls the male modes of both sex determination and X chromosome dosage compensation in C. elegans

1988 • 163 citations

Molecular cloning of the muscle gene unc-22 in Caenorhabditis elegans by Tc1 transposon tagging.

1986 • 151 citations

Localization and sequence of a vaccinia virus gene required for multiplication in human cells.

1986 • 126 citations

ACTIVITY OF THE SEX-DETERMINING GENE tra-2 IS MODULATED TO ALLOW SPERMATOGENESIS IN THE C. ELEGANS HERMAPHRODITE

1986 • 113 citations

Local function of the notch gene for embryonic ectodermal pathway choice in drosophila

1986 • 100 citations

Molecular genetics of the Caenorhabditis elegans heterochronic gene lin-14.

1989 • 91 citations

The Caenorhabditis elegans gene sdc-2 controls sex determination and dosage compensation in XX animals.

1989 • 86 citations

SEX DETERMINATION AND DOSAGE COMPENSATION IN CAENORHABDITIS ELEGANS

1987 • 80 citations

sdc-1: A link between sex determination and dosage compensation in C. elegans

1987 • 80 citations

Extrachromosomal copies of transposon Tc1 in the nematode Caenorhabditis elegans.

1984 • 71 citations

Molecular cloning and transcript analysis of fem-3, a sex-determination gene in Caenorhabditis elegans.

1988 • 67 citations

Correlation of the physical and genetics maps in the lin-12 region of caenorahabditis elegans

1987 • 51 citations

Cell-cell interactions that specify certain cell fates in C. elegans development

1989 • 39 citations

Antibodies directed against a synthetic peptide enable detection of a protein encoded by a vaccinia virus host range gene that is conserved within the Orthopoxvirus genus

1989 • 14 citations

Spectrum of 32P-induced mutants of Caenorbabditis elegans

1981 • 12 citations

Genetic analysis of sex determination in the nematode Caenorhabditis elegans.

1986 • 7 citations