Nuclear Localization of v-Abl Leads to Complex Formation with Cyclic AMP Response Element (CRE)-Binding Protein and Transactivation through CRE Motifs

High-efficiency transformation of mammalian cells by plasmid DNA.

1987 • 5,377 citations

A New Consistent Chromosomal Abnormality in Chronic Myelogenous Leukaemia identified by Quinacrine Fluorescence and Giemsa Staining

1973 • 4,217 citations

The Leucine Zipper: A Hypothetical Structure Common to a New Class of DNA Binding Proteins

1988 • 3,479 citations

Oncogenes and signal transduction

1991 • 2,816 citations

A minute chromosome in human chronic granulocytic leukemia

1960 • 2,329 citations

SH2 and SH3 Domains: Elements that Control Interactions of Cytoplasmic Signaling Proteins

1991 • 1,931 citations

Fused transcript of abl and bcr genes in chronic myelogenous leukaemia

1985 • 1,650 citations

CREB: a Ca ²⁺ -Regulated Transcription Factor Phosphorylated by Calmodulin-Dependent Kinases

1991 • 1,476 citations

Identification of a cyclic-AMP-responsive element within the rat somatostatin gene.

1986 • 1,424 citations

Binding of a nuclear protein to the cyclic-AMP response element of the somatostatin gene

1987 • 1,364 citations

Phosphorylation-induced binding and transcriptional efficacy of nuclear factor CREB

1988 • 1,321 citations

The regulation of transcription by phosphorylation

1992 • 1,316 citations

Cyclic AMP and the induction of eukaryotic gene transcription.

1988 • 1,041 citations

Scissors-Grip Model for DNA Recognition by a Family of Leucine Zipper Proteins

1989 • 996 citations

Transcriptional regulation

1991 • 893 citations

High-Efficiency Transformation of Mammalian Cells by Plasmid DNA

1987 • 729 citations

CREM gene: Use of alternative DNA-binding domains generates multiple antagonists of cAMP-induced transcription

1991 • 655 citations

Identification of cellular proteins that can interact specifically with the T/ElA-binding region of the retinoblastoma gene product

1991 • 541 citations

Monoclonal antibodies to herpes simplex virus type 1 proteins, including the immediate-early protein ICP 4

1981 • 436 citations

The Oct-1 homoeodomain directs formation of a multiprotein-DNA complex with the HSV transactivator VP16

1989 • 434 citations

The mouse type IV c-abl gene product is a nuclear protein, and activation of transforming ability is associated with cytoplasmic localization

1989 • 427 citations

Lymphosarcoma: virus-induced thymic-independent disease in mice.

1970 • 414 citations

Dominant negative MYC blocks transformation by ABL oncogenes

1992 • 410 citations

A C-terminal protein-binding domain in the retinoblastoma protein regulates nuclear c-Abl tyrosine kinase in the cell cycle

1993 • 402 citations

Neoplastic transformation of mast cells by Abelson-MuLV: abrogation of IL-3 dependence by a nonautocrine mechanism

1985 • 330 citations

The activation domain of transcription factor PU.1 binds the retinoblastoma (RB) protein and the transcription factor TFIID in vitro: RB shows sequence similarity to TFIID and TFIIB.

1993 • 317 citations

The retinoblastoma gene product regulates Sp1-mediated transcription.

1992 • 253 citations

Nucleotide sequence of Abelson murine leukemia virus genome: structural similarity of its transforming gene product to other onc gene products with tyrosine-specific kinase activity.

1983 • 253 citations

Signal transduction from cell surface to nucleus in development and disease

1992 • 246 citations

Characterization of motifs which are critical for activity of the cyclic AMP-responsive transcription factor CREB.

1991 • 229 citations

The mouse c-abl locus: Molecular cloning and characterization

1984 • 223 citations

Tyrosine phosphorylation of mammalian RNA polymerase II carboxyl-terminal domain.

1993 • 206 citations

Cell Cycle—Regulated Binding of c-Abl Tyrosine Kinase to DNA

1992 • 202 citations

The cAMP-regulated transcription factor CREB interactswith a component of the TFIID complex.

1994 • 192 citations

The human cellular abl gene product in the chronic myelogenous leukemia cell line K562 has an associated tyrosine protein kinase activity

1985 • 184 citations

Distinct activation domains within cAMP response element-binding protein (CREB) mediate basal and cAMP-stimulated transcription

1993 • 166 citations

Direct correlation between a negative autoregulatory response element at the cap site of the herpes simplex virus type 1 IE175 (alpha 4) promoter and a specific binding site for the IE175 (ICP4) protein

1988 • 149 citations

Evidence for regulation of the human ABL tyrosine kinase by a cellular inhibitor.

1991 • 149 citations

Signal transduction and gene control: the cAMP pathway.

1992 • 142 citations

Tyrosine kinase oncogenes abrogate interleukin-3 dependence of murine myeloid cells through signaling pathways involving c-myc: conditional regulation of c-myc transcription by temperature-sensitive v-abl.

1989 • 136 citations

Structural and functional characterization of the transforming growth factor beta 3 promoter. A cAMP-responsive element regulates basal and induced transcription.

1990 • 124 citations

Stimulation of factor-dependent myeloid cell lines with interleukin 3 induces tyrosine phosphorylation of several cellular substrates.

1988 • 117 citations

Structure of the Human Vasoactive Intestinal Polypeptide Gene

1985 • 116 citations

Transcriptional Regulation of the Transforming Growth Factor β1 Promotor by v-src Gene Products Is Mediated through the AP-1 Complex

1990 • 115 citations

Abelson murine leukemia virus: molecular cloning of infectious integrated proviral DNA.

1981 • 106 citations

Bidirectional effects of transforming growth factor beta (TGF-beta) on colony-stimulating factor-induced human myelopoiesis in vitro: differential effects of distinct TGF-beta isoforms

1991 • 100 citations

Abelson murine leukemia virus mutants with alterations in the virus-specific P120 molecule

1980 • 90 citations

Transfection of Fibroblasts by Cloned Abelson Murine Leukemia Virus DNA and Recovery of Transmissible Virus by Recombination with Helper Virus

1982 • 78 citations

Isolation and complete nucleotide sequence of the gene for bovine parathyroid hormone

1984 • 66 citations

Oncogenic v-Abl tyrosine kinase can inhibit or stimulate growth, depending on the cell context.

1992 • 64 citations

Long terminal repeat structure of an american isolate of type I human T-cell leukemia virus

1984 • 63 citations

Differential expression of the human gonadotropin alpha gene in ectopic and eutopic cells.

1985 • 63 citations

Characterization of Motifs Which Are Critical for Activity of the Cyclic AMP-Responsive Transcription Factor CREB

1991 • 57 citations

The Retinoblastoma Gene Product Regulates Sp1-Mediated Transcription

1992 • 55 citations

Tyrosine Kinase Oncogenes Abrogate Interleukin-3 Dependence of Murine Myeloid Cells through Signaling Pathways Involving c-myc: Conditional Regulation of c-myc Transcription by Temperature-Sensitive v-abl

1989 • 28 citations

Biologic properties of factor-independent nonadherent hematopoietic and adherent preadipocyte cell lines derived from continuous bone marrow culture

1984 • 25 citations

5 Phosphorylation of RNA Polymerase II as a Transcriptional Regulatory Mechanism

1992 • 21 citations

Recombinants within the Tyrosine Kinase Region of v-abl and v-src Identify a v-abl Segment That Confers Lymphoid Specificity

1988 • 19 citations

Differential Expression of the Human Gonadotropin α Gene in Ectopic and Eutopic Cells

1985 • 17 citations

Introduction of v-abl oncogene induces monocytic differentiation of an IL-3-dependent myeloid progenitor cell line.

1990 • 12 citations

Structures and Activities of Activated abl Oncogenes

1989 • 6 citations

Transformation of NIH3T3 cells by A-MuLV proviral DNA: effect of plasmid linearization and carrier DNA on transformation efficiency.

1989 • 4 citations