Early invasiveness characterizes metastatic carcinoid tumors in transgenic mice.

A genetic model for colorectal tumorigenesis

1990 • 11,800 citations

The Clonal Evolution of Tumor Cell Populations

1976 • 6,310 citations

Manipulating the mouse embryo: A laboratory manual

1986 • 4,548 citations

Cancer metastasis and angiogenesis: An imbalance of positive and negative regulation

1991 • 2,774 citations

Induction of angiogenesis during the transition from hyperplasia to neoplasia

1989 • 1,912 citations

Number and evolutionary conservation of α- and β-tubulin and cytoplasmic β- and γ-actin genes using specific cloned cDNA probes

1980 • 1,884 citations

A new variant of glycoprotein CD44 confers metastatic potential to rat carcinoma cells

1991 • 1,685 citations

Tumor invasion and metastases--role of the extracellular matrix: Rhoads Memorial Award lecture.

1986 • 1,408 citations

Heritable formation of pancreatic β-cell tumours in transgenic mice expressing recombinant insulin/simian virus 40 oncogenes

1985 • 1,292 citations

Differential plasmid rescue from transgenic mouse DNAs into Escherichia coli methylation-restriction mutants.

1990 • 1,149 citations

Oncogenes, antioncogenes, and the molecular bases of multistep carcinogenesis.

1989 • 961 citations

Tumor suppressor genes

1991 • 775 citations

THE MOLECULAR GENETICS OF CELLULAR ONCOGENES

1984 • 765 citations

GENETICS OF HUMAN CANCER

1986 • 565 citations

DNA Tumor Viruses

1982 • 550 citations

Beta-cell lines derived from transgenic mice expressing a hybrid insulin gene-oncogene.

1988 • 523 citations

The experimental study of tumor progression: a review.

1954 • 522 citations

Hybrid insulin genes reveal a developmental lineage for pancreatic endocrine cells and imply a relationship with neurons

1988 • 455 citations

Cancer metastasis: tumor cell and host organ properties important in metastasis to specific secondary sites

1988 • 405 citations

Pancreatic neoplasia induced by ras expression in acinar cells of transgenic mice

1987 • 271 citations

Development of neuroendocrine tumors in the gastrointestinal tract of transgenic mice. Heterogeneity of hormone expression.

1990 • 265 citations

Intestinal epithelial differentiation: new insights from chimeric and transgenic mice.

1989 • 231 citations

Dissecting Multistep Tumorigenesis in Transgenic Mice

1988 • 215 citations

Characterization of the two nonallelic genes encoding mouse preproinsulin

1986 • 165 citations

Endothelial cell tumors develop in transgenic mice carrying polyoma virus middle T oncogene

1987 • 140 citations

Transgenic Mice and Oncogenesis

1988 • 125 citations

Nonrandom loss of chromosome 15 in Syrian hamster tumours induced by v-Ha-ras plus v-myc oncogenes

1985 • 106 citations

Proliferation, senescence, and neoplastic progression of ? cells in hyperplasic pancreatic islets

1988 • 101 citations

Complex lymphoid and epithelial thymic tumours in Thyl-myc transgenic mice

1989 • 54 citations

Host and tumour factors in cancer metastasis

1990 • 39 citations

Cell-heritable stages of tumor progression in transgenic mice harboring the bovine papillomavirus type 1 genome.

1989 • 35 citations

Metastatic Hibernomas in Transgenic Mice Expressing an α-Amylase-SV40 T Antigen Hybrid Gene

1989 • 30 citations

Genetic background affects integration frequency of ecotropic proviral sequences into the mouse germ line

1986 • 22 citations

Effects of polyoma virus oncogenes in transgenic mice.

1989 • 14 citations