Mineralocorticoid Blockade Reduces Vascular Injury in Stroke-Prone Hypertensive Rats

Essential Hypertension: Renin and Aldosterone, Heart Attack and Stroke

1972 • 1,098 citations

Establishment of the strokeprone spontaneously hypertensive rat (SHR)

1972 • 606 citations

Role of aldosterone in the remnant kidney model in the rat.

1996 • 473 citations

Three new epoxy-spirolactone derivatives: characterization in vivo and in vitro.

1987 • 318 citations

Regulation of Aldosterone Secretion

1988 • 311 citations

Antifibrotic effects of spironolactone in preventing myocardial fibrosis in systemic arterial hypertension

1993 • 275 citations

Increased endothelial albumin permeability mediated by protein kinase C activation.

1990 • 271 citations

Regional Myocardial Blood Flow in Lambs with Concentric Right Ventricular Hypertrophy

1974 • 255 citations

Determinants of cardiac fibrosis in experimental hypermineralocorticoid states

1995 • 234 citations

Malignant hypertension produced by treatment with desoxycorticosterone acetate and sodium chloride

1943 • 219 citations

High Glucose Concentrations Increase Endothelial Cell Permeability via Activation of Protein Kinase Cα

1997 • 206 citations

Malignant hypertension resulting from deoxycorticosterone acetate and salt excess: role of renin and sodium in vascular changes.

1975 • 203 citations

Intracerebroventricular Infusion of Aldosterone Induces Hypertension in Rats*

1986 • 178 citations

Potassium reduces cerebral hemorrhage and death rate in hypertensive rats, even when blood pressure is not lowered.

1985 • 158 citations

Enalapril prevents stroke and kidney dysfunction in salt-loaded stroke-prone spontaneously hypertensive rats.

1989 • 143 citations

Aldosterone enhances angiotensin II receptor binding and inositol phosphate responses.

1992 • 140 citations

Left Ventricular Fibrosis in Renovascular Hypertensive Rats

1995 • 125 citations

Relation of plasma renin to end organ damage and to protection of K+ feeding in stroke-prone hypertensive rats.

1990 • 123 citations

Rapid Aldosterone Signaling in Vascular Smooth-Muscle Cells - Involvement of Phospholipase-C, Diacylglycerol and Protein-Kinase-C-α

1995 • 114 citations

Therapeutic Benefit of Captopril in Salt-Loaded Stroke-Prone Spontaneously Hypertensive Rats Is Independent of Hypotensive Effect

1991 • 100 citations

Stroke-prone spontaneously hypertensive rats as an experimental model of malignant hypertension

1980 • 93 citations

Stroke prevention by losartan in stroke-prone spontaneously hypertensive rats.

1993 • 88 citations

Experimental Vascular Disease Elicited by Aldosterone and Renin

1962 • 80 citations

Control of blood pressure and end-organ damage in maturing salt-loaded stroke-prone spontaneously hypertensive rats by oral angiotensin II receptor blockade

1993 • 73 citations

Effects of nifedipine and enalapril on glomerular injury in rats with deoxycorticosterone-salt hypertension

1990 • 71 citations

What Is the Role of the Central Nervous System in Mineralocorticoid Hypertension?

1991 • 68 citations

Renin-angiotensin system in stroke-prone spontaneously hypertensive rats

1979 • 62 citations

The Role of Blood Pressure and Aldosterone in the Production of Hemorrhagic Stroke in Captopril-Treated Hypertensive Rats

1997 • 61 citations

Recent progress in understanding aldosterone secretion

1997 • 48 citations

Stroke-prone spontaneously hypertensive rats as an experimental model of malignant hypertension

1982 • 47 citations

Aldosterone, Salt and Cardiac Fibrosis

1997 • 44 citations

Prophylactic effect of imidapril on stroke in stroke-prone spontaneously hypertensive rats.

1993 • 42 citations

Renal function in rats with angiotensin li-salt-induced hypertension: effect of thromboxane synthesis inhibition and receptor blockade

1990 • 40 citations

Dihydropyridines versus other agents in the treatment of hypertension in the elderly. Part 3

1993 • 32 citations

High Potassium Diets Reduce Macrophage Adherence to the Vascular Wall in Stroke-Prone Spontaneously Hypertensive Rats

1995 • 31 citations

Quinapril Prevents Stroke Both During and After the Treatment Period in Stroke-Prone Spontaneously Hypertensive Rats

1993 • 26 citations

The antiproteinuric action of enalapril in stroke-prone spontaneously hypertensive rats is unrelated to alterations in urinary prostaglandins.

1992 • 19 citations

Effect of spironolactone on electrolytes, renin, ACTH and corticosteroids in the rat

1984 • 15 citations

Complete Prevention of Cerebral Accidents in Malignant Hypertension

1956 • 13 citations

Accelerating effects of dexamethasone and thyroxine on hypertension without accompanying stroke in stroke-prone spontaneously hypertensive rats

1979 • 11 citations

Effects of diuretics on stroke development in Kyoto–Wistar stroke-prone spontaneously hypertensive rats

1991 • 9 citations

Effect of Ifetroban, a Thromboxane a₂Receptor Antagonist, in Stroke-Prone Spontaneously Hypertensive Rats

1996 • 7 citations