Effect of spironolactone on electrolytes, renin, ACTH and corticosteroids in the rat

STEROID-PROTEIN CONJUGATES

1957 • 798 citations

Measurement of Renin Activity, Concentration and Substrate in Rat Plasma by Radioimmunoassay of Angiotensin I

1972 • 458 citations

A Radioimmunoassay for Rat Plasma ACTH

1971 • 433 citations

The simultaneous measurement of aldosterone, cortisol, and corticosterone in human peripheral plasma by displacement analysis.

1972 • 222 citations

Pathophysiology of Spironolactone-Induced Gynecomastia

1977 • 187 citations

Regulation of Aldosterone Biosynthesis

1988 • 166 citations

BLOCKING THE RENAL ELECTROLYTE EFFECTS OF MINERALOCORTICOIDS WITH AN ORALLY ACTIVE STEROIDAL SPIROLACTONE

1960 • 111 citations

Regulation of Aldosterone Biosynthesis

1971 • 109 citations

Mechanism of the antimineralocorticoid effects of spirolactones

1981 • 86 citations

Effects of Spironolactone, Canrenone and Canrenoate-K on Cytochrome P450, and 11β- and 18-Hydroxylation in Bovine and Human Adrenal Cortical Mitochondria1¹

1976 • 69 citations

Spironolactone and cytochrome P-450: Impairment of steroid 21-hydroxylation in the adrenal cortex

1976 • 58 citations

A simple and efficient method for raising steroid antibodies in rabbits

1978 • 52 citations

Stimulation of aldosterone production in vitro and its inhibition by spironolactone

1972 • 49 citations

Evaluation of sodium and potassium balance in rats.

1972 • 46 citations

On the mechanism of the inhibitory action of the spirolactone SC 9376 (aldadiene) on the production of corticosteroids in rat adrenals in vitro

1973 • 44 citations

Corticosteroid production in vitro by adrenal tissue from rats with inherited hypothalamic diabetes insipidus (brattleboro strain)

1978 • 31 citations

Spironolactone antagonism of aldosterone action on Na+ transport and RNA metabolism in toad bladder epithelium

1977 • 29 citations

Antiandrogenic Effects of Spironolactone: Hormonal and Ultrastructural Studies in Dogs and Men

1978 • 26 citations

Plasma Corticosteroid Concentrations during Spironolactone Administration: Evidence for Adrenal Biosynthetic Blockade in Man*

1981 • 26 citations

EFFECT OF ALDOSTERONE-ANTAGONIST, SC 8109, ON THE SECRETION OF ALDOSTERONE IN NORMAL RATS

1959 • 22 citations

Increased Plasma 11-Deoxycorticosterone During Spironolactone Medication

1977 • 19 citations

Influence of Spironolactone on Endogenous Steroid Metabolism in Man

1976 • 16 citations

INTERFERENCE OF SPIRONOLACTONE IN 11-DEOXYCORTICOSTERONE RADIOASSAYS.

1975 • 13 citations

Aldosterone plasma radioimmunoassay interference by a spirolactone matabolite

1975 • 12 citations

Effects of steroid-17-spirolactones on aldosterone secretion, excretion, and metabolism in man.

1961 • 12 citations

Effect of Spironolactone on Aldosterone Regulation in Man

1980 • 12 citations

Effect of the aldosterone antagonist canrenone on plasma aldosterone concentration and plasma renin activity, and on the excretion of aldosterone and electrolytes by man

1976 • 11 citations

EFFECT OF SPIRONOLACTONE AND ITS MAIN METABOLITE CANRENONE ON THE RENIN-ANGIOTENSIN-ALDOSTERONE-SYSTEM DURING LONG-TERM TREATMENT IN RATS

1979 • 8 citations

Effects of repeated administration of potassium canrenoate (SC-14266) on serum gonadotrophin, prolactin, testosterone and progesterone in male rats

1980 • 4 citations

Comparison of the urinary excretion of free aldosterone and its acid-labile conjugate in rats during experimental hyperaldosteronism

1979 • 4 citations

Faecal Sodium/Potassium Ratio and Aldosteronism in Experimental Hypertension in the Rat

1972 • 4 citations

Reduced Response of Plasma Aldosterone to Acute ACTH Stimulation during Long-Term Treatment with Spironolactone in Essential Hypertension

1979 • 3 citations

Separation of 5α-pregnan-3,20-dione and progesterone on sephadex LH-20

1975 • 3 citations

LONG TERM SPIRONOLACTONE AND THE ADRENAL CORTEX IN ESSENTIAL HYPERTENSION

1980 • 2 citations

In vitro study of frog (rana ridibunda pallas) interrenal function by use of a simplified perifusion system—VI. Inhibition of aldosterone biosynthesis by SC 14266

1981 • 2 citations

Aldosterone plasma radioimmunoassay interference by a spirolactone metabolite

1975 • 1 citations