Cholestatic expression pattern of sinusoidal and canalicular organic anion transport systems in primary cultured rat hepatocytes
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References (50)
Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4
1970 • 253,849 citations
Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction
1987 • 64,270 citations
Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
1987 • 45,673 citations
Measurement of protein using bicinchoninic acid
1985 • 17,516 citations
A simple, rapid, and sensitive DNA assay procedure
1980 • 5,006 citations
HIGH-YIELD PREPARATION OF ISOLATED RAT LIVER PARENCHYMAL CELLS
1969 • 4,428 citations
The Sister of P-glycoprotein Represents the Canalicular Bile Salt Export Pump of Mammalian Liver
1998 • 933 citations
Molecular Pathogenesis of Cholestasis
1998 • 669 citations
Molecular Pathogenesis of Cholestasis
2004 • 622 citations
Expression cloning of a rat liver Na(+)-independent organic anion transporter.
1994 • 535 citations
The rat canalicular conjugate export pump (Mrp2) is down-regulated in intrahepatic and obstructive cholestasis
1997 • 502 citations
Functional expression cloning and characterization of the hepatocyte Na+/bile acid cotransport system.
1991 • 479 citations
Isolation of a multispecific organic anion and cardiac glycoside transporter from rat brain
1997 • 396 citations
Hepatobiliary secretion of organic compounds; molecular mechanisms of membrane transport
1995 • 385 citations
Up-regulation of the multidrug resistance genes,Mrp1andMdr1b, and down-regulation of the organic anion transporter, Mrp2, and the bile salt transporter, Spgp, in endotoxemic rat liver
1998 • 361 citations
Hepatic Transport of Bile Salts
2000 • 286 citations
Expression of the bile salt export pump is maintained after chronic cholestasis in the rat
2000 • 251 citations
Down-regulation of expression and function of the rat liver Na+/bile acid cotransporter in extrahepatic cholestasis
1996 • 251 citations
In situ localization of the hepatocytic na+/taurocholate cotransporting polypeptide in rat liver
1994 • 221 citations
Reconstruction of hepatic organoid by rat small hepatocytes and hepatic nonparenchymal cells
1999 • 220 citations
Biliary excretion in primary rat hepatocytes cultured in a collagen-sandwich configuration
1999 • 219 citations
Transport Function and Hepatocellular Localization of mrp6 in Rat Liver
2000 • 218 citations
Localization and function of the organic anion–transporting polypeptide Oatp2 in rat liver
1999 • 209 citations
Ethinyl estradiol cholestasis involves alterations in expression of liver sinusoidal transporters
1996 • 162 citations
Molecular regulation of hepatocellular transport systems in cholestasis
1999 • 147 citations
Identification of organic anion transporting polypeptide 4 (Oatp4) as a major full-length isoform of the liver-specific transporter-1 (rlst-1) in rat liver
2000 • 144 citations
Increased levels of the multidrug resistance protein in lateral membranes of proliferating hepatocyte-derived cells
1997 • 141 citations
Polyspecific substrate uptake by the hepatic organic anion transporter Oatp1 in stably transfected CHO cells
1999 • 138 citations
Polarized amino acid transport by an epithelial cell line of renal origin (LLC-PK1). The basolateral systems.
1982 • 137 citations
Regulation of Hepatic Transport Systems Involved in Bile Secretion During Liver Regeneration in Rats
1999 • 122 citations
The secretory function of the liver: new aspects of hepatobiliary transport
1998 • 121 citations
Effect of antisense oligonucleotides on the expression of hepatocellular bile acid and organic anion uptake systems in Xenopus laevis oocytes
1996 • 120 citations
A domain-specific marker for the hepatocyte plasma membrane: localization of leucine aminopeptidase to the bile canalicular domain.
1983 • 111 citations
Cholestatic expression pattern of sinusoidal and canalicular organic anion transport systems in primary cultured rat hepatocytes
2001 • 107 citations
Parallel decrease of Na+ -taurocholate cotransport and its encoding mRNA in primary cultures of rat hepatocytes
1993 • 104 citations
Isolation and characterization of rough endoplasmic reticulum associated with mitochondria from normal rat liver
1981 • 103 citations
Liver stem cells: a two compartment system
1998 • 99 citations
Expression of the liver Na+-independent organic anion transporting polypeptide (oatp-1) in rats with bile duct ligation
1997 • 99 citations
Differential expression of basolateral and canalicular organic anion transporters during regeneration of rat liver
1999 • 95 citations
Functional expression of the rat liver canalicular isoform of the multidrug resistance‐associated protein
1997 • 91 citations
Partial maintenance of taurocholate uptake by adult rat hepatocytes cultured in a collagen sandwich configuration.
1998 • 84 citations
Polarized amino acid transport by an epithelial cell line of renal origin (LLC-PK1). The apical systems.
1983 • 71 citations
Hepatocellular transport of bile acids. Evidence for distinct subcellular localizations of electrogenic and ATP-dependent taurocholate transport in rat hepatocytes.
1994 • 62 citations
Dexamethasone- and osmolarity-dependent expression of the multidrug-resistance protein 2 in cultured rat hepatocytes1
1999 • 61 citations
Regulation of Bile Salt Export Pump mRNA Levels by Dexamethasone and Osmolarity in Cultured Rat Hepatocytes
1999 • 55 citations
Alterations of bile acid and bumetanide uptake during culturing of rat hepatocytes
1990 • 43 citations
Glutathione S-conjugate transport in hepatocytes entering the cell cycle is preserved by a switch in expression from the apical MRP2 to the basolateral MRP1 transporting protein
1999 • 41 citations
Identification and characterization of a basolateral dicarboxylate/cholate antiport system in rat hepatocytes
1995 • 26 citations
Upregulation of the multidrug resistance genes mrp1 and mdr1b and downregulation of the organic anion transporter mrp2 and bile salt transporter spgp in endotoxemic rat liver
1998 • 26 citations
Dexamethasone- and osmolarity-dependent expression of the multidrug-resistance protein 2 in cultured rat hepatocytes1
1999 • 23 citations