Glutamate Signaling System in Bone

Glutamate neurotoxicity and diseases of the nervous system

1988 • 7,257 citations

Osteoclast differentiation and activation

2003 • 6,172 citations

Osf2/Cbfa1: A Transcriptional Activator of Osteoblast Differentiation

1997 • 4,191 citations

Targeted Disruption of Results in a Complete Lack of Bone Formation owing to Maturational Arrest of Osteoblasts

1997 • 4,168 citations

Cloned Glutamate Receptors

1994 • 3,989 citations

Glutamate uptake

2001 • 3,867 citations

Bone Resorption by Osteoclasts

2000 • 3,797 citations

Leptin Regulates Bone Formation via the Sympathetic Nervous System

2002 • 1,651 citations

Control of osteoblast function and regulation of bone mass

2003 • 1,414 citations

Sequence and expression of a metabotropic glutamate receptor

1991 • 1,200 citations

The Osteoblast: A Sophisticated Fibroblast under Central Surveillance

2000 • 1,115 citations

Glutamate receptor function in learning and memory

2003 • 925 citations

The identification of vesicular glutamate transporter 3 suggests novel modes of signaling by glutamate

2002 • 548 citations

Complementary distribution of vesicular glutamate transporters in the central nervous system

2002 • 391 citations

Evidence for a dense and intimate innervation of the bone tissue, including glutamate-containing fibers

1999 • 249 citations

Glutamate Receptors Are Expressed by Bone Cells and Are Involved in Bone Resorption

1998 • 237 citations

Mechanically regulated expression of a neural glutamate transporter in bone: A role for excitatory amino acids as osteotropic agents?

1997 • 214 citations

Glutamate as a CNS transmitter. II. Regulation of synthesis in the releasable pool

1979 • 155 citations

The glutamate receptor antagonist MK801 modulates bone resorptionin vitroby a mechanism predominantly involving osteoclast differentiation

1999 • 107 citations

Functional characterization of N-methyl-d-aspartic acid-gated channels in bone cells

1999 • 103 citations

Modulation of cellular differentiation by N ‐methyl‐ <scp>d</scp> ‐aspartate receptors in osteoblasts

2003 • 100 citations

Expression of Functional Metabotropic Glutamate Receptors in Primary Cultured Rat Osteoblasts

2000 • 94 citations

Regulation of spontaneous glutamate release activity in osteoblastic cells and its role in differentiation and survival: evidence for intrinsic glutamatergic signaling in bone

2001 • 85 citations

Group III Metabotropic Glutamate Receptors in Rat Cultured Calvarial Osteoblasts

2001 • 80 citations

Sequence and expression of a metabotropic glutamate receptor

1992 • 66 citations

Consolidation of transient ionotropic glutamate signals through nuclear transcription factors in the brain

2001 • 58 citations

The open reading frame of the Na⁺‐dependent glutamate transporter GLAST‐1 is expressed in bone and a splice variant of this molecule is expressed in bone and brain

2000 • 57 citations

Facilitation of glutamate release by ionotropic glutamate receptors in osteoblasts

2002 • 56 citations

Glutamate Does Not Play a Major Role in Controlling Bone Growth

2001 • 51 citations

Demonstration of expression of mRNA for particular AMPA and kainate receptor subunits in immature and mature cultured rat calvarial osteoblasts

2002 • 47 citations