The Osteoblast: A Sophisticated Fibroblast under Central Surveillance

Osf2/Cbfa1: A Transcriptional Activator of Osteoblast Differentiation

1997 • 4,191 citations

Targeted Disruption of Results in a Complete Lack of Bone Formation owing to Maturational Arrest of Osteoblasts

1997 • 4,168 citations

Bone Resorption by Osteoclasts

2000 • 3,797 citations

Cbfa1, a Candidate Gene for Cleidocranial Dysplasia Syndrome, Is Essential for Osteoblast Differentiation and Bone Development

1997 • 2,784 citations

Leptin Inhibits Bone Formation through a Hypothalamic Relay

2000 • 2,045 citations

Regulation of Rate of Cartilage Differentiation by Indian Hedgehog and PTH-Related Protein

1996 • 1,952 citations

Principles of Bone Biology

2019 • 1,699 citations

Increased bone formation in osteocalcin-deficient mice

1996 • 1,692 citations

Indian hedgehog signaling regulates proliferation and differentiation of chondrocytes and is essential for bone formation

1999 • 1,682 citations

Leptin levels reflect body lipid content in mice: Evidence for diet-induced resistance to leptin action

1995 • 1,630 citations

Mutations Involving the Transcription Factor CBFA1 Cause Cleidocranial Dysplasia

1997 • 1,463 citations

Lethal skeletal dysplasia from targeted disruption of the parathyroid hormone-related peptide gene.

1994 • 1,138 citations

Dominant and recessive inheritance of morbid obesity associated with melanocortin 4 receptor deficiency

2000 • 795 citations

A Cbfa1-dependent genetic pathway controls bone formation beyond embryonic development

1999 • 777 citations

Msx2 deficiency in mice causes pleiotropic defects in bone growth and ectodermal organ formation

2000 • 722 citations

Obesity in the new millennium

2000 • 707 citations

Missense mutations abolishing DNA binding of the osteoblast-specific transcription factor OSF2/CBFA1 in cleidocranial dysplasia

1997 • 574 citations

Two Distinct Osteoblast-Specific cis-Acting Elements Control Expression of a Mouse Osteocalcin Gene

1995 • 564 citations

Maturational disturbance of chondrocytes inCbfa1-deficient mice

1999 • 561 citations

Hoxa-2 mutant mice exhibit homeotic transformation of skeletal elements derived from cranial neural crest

1993 • 556 citations

Unraveling the central nervous system pathways underlying responses to leptin

1998 • 520 citations

Disruption of the fibroblast growth factor-2 gene results in decreased bone mass and bone formation

2000 • 467 citations

Regulation of chondrocyte differentiation by Cbfa1

1999 • 453 citations

Craniofacial, vestibular and bone defects in mice lacking the Distal-less-related gene Dlx5

1999 • 443 citations

Distal-less encodes a homoeodomain protein required for limb development in Drosophila

1989 • 389 citations

Overexpression of ΔFosB transcription factor(s) increases bone formation and inhibits adipogenesis

2000 • 333 citations

Cbfa1 is required for epithelial-mesenchymal interactions regulating tooth development in mice

1999 • 327 citations

Increased bone formation and osteosclerosis in mice overexpressing the transcription factor Fra-1

2000 • 312 citations

The Drosophila segmentation gene runt encodes a novel nuclear regulatory protein that is also expressed in the developing nervous system.

1990 • 299 citations

Cloning and characterization of two members of the vertebrate Dlx gene family.

1994 • 276 citations

The murine Bapx1 homeobox gene plays a critical role in embryonic development of the axial skeleton and spleen

1999 • 244 citations

Dissociation between bone resorption and bone formation in osteopenic transgenic mice

1998 • 225 citations

Vertebral postmenopausal bone loss is reduced in overweight women: a longitudinal study in 155 early postmenopausal women.

1993 • 215 citations

Hoxa-2 restricts the chondrogenic domain and inhibits bone formation during development of the branchial area

1998 • 210 citations

Patterning of cells in the Drosophila eye by Lozenge, which shares homologous domains with AML1.

1996 • 187 citations

A New Transcription Factor Family Associated with Human Leukemias

1995 • 164 citations

The Drosophila segmentation gene runt acts as a position-specific numerator element necessary for the uniform expression of the sex-determining gene Sex-lethal.

1991 • 139 citations

Bapxl: an evolutionary conserved homologue of the Drosophila bagpipe homeobox gene is expressed in splanchnic mesoderm and the embryonic skeleton

1997 • 107 citations

Connective Tissue Cells

1964 • 84 citations

Characterization of Osf1, an Osteoblast-specific Transcription Factor Binding to a Critical cis-acting Element in the MouseOsteocalcin Promoters

1999 • 74 citations

Radiological features in generalized lipodystrophy

1996 • 64 citations

Animal model: Skeletal anomalies in mice with cleidocranial dysplasia

1987 • 43 citations