A rat gene with sequence homology to the Drosophila gene hairy is rapidly induced by growth factors known to influence neuronal differentiation.

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor.

1976 • 5,526 citations

Stimulation of 3T3 cells induces transcription of the c-fos proto-oncogene

1984 • 3,150 citations

Induction of apoptosis in fibroblasts by c-myc protein

1992 • 2,977 citations

A new DNA binding and dimerization motif in immunoglobulin enhancer binding, daughterless, MyoD, and myc proteins

1989 • 2,706 citations

Homeobox genes and axial patterning

1992 • 2,688 citations

The regulation and function of c-fos and other immediate early genes in the nervous system

1990 • 2,392 citations

The protein Id: A negative regulator of helix-loop-helix DNA binding proteins

1990 • 2,273 citations

Interactions between heterologous helix-loop-helix proteins generate complexes that bind specifically to a common DNA sequence

1989 • 1,876 citations

pl Bl5: A cDNA Clone of the Rat mRNA Encoding Cyclophilin

1988 • 1,039 citations

The long and the short of long–term memory—a molecular framework

1986 • 1,026 citations

The MyoD DNA binding domain contains a recognition code for muscle-specific gene activation

1990 • 794 citations

A transcript from a Drosophila pattern gene predicts a protein homologous to the transforming growth factor-β family

1987 • 756 citations

Two rat homologues of Drosophila achaete-scute specifically expressed in neuronal precursors

1990 • 533 citations

Growth factors and membrane depolarization activate distinct programs of early response gene expression: dissociation of fos and jun induction.

1989 • 502 citations

The achaete-scute gene complex of D. melanogaster: Conserved Domains in a subset of genes required for neurogenesis and their homology to myc

1987 • 501 citations

Nerve growth factor-induced fiber outgrowth from isolated rat adrenal chromaffin cells: impairment by glucocorticoids.

1978 • 468 citations

Distribution of the wingless gene product in drosophila embryos: A protein involved in cell-cell communication

1989 • 452 citations

Proneural clusters of achaete-scute expression and the generation of sensory organs in the Drosophila imaginal wing disc.

1991 • 444 citations

daughterless, a Drosophila gene essential for both neurogenesis and sex determination, has sequence similarities to myc and the achaete-scute complex

1988 • 442 citations

Mammalian achaete-scute homolog 1 is transiently expressed by spatially restricted subsets of early neuroepithelial and neural crest cells.

1991 • 441 citations

Molecular cloning of sequences from wingless , a segment polarity gene in Drosophila : the spatial distribution of a transcript in embryos

1987 • 437 citations

extramacrochaetae, a negative regulator of sensory organ development in Drosophila, defines a new class of helix-loop-helix proteins

1990 • 407 citations

Environmental influences in the development of neural crest derivatives: glucocorticoids, growth factors, and chromaffin cell plasticity

1985 • 406 citations

Regulation of achaete-scute gene expression and sensory organ pattern formation in the Drosophila wing.

1991 • 390 citations

The Drosophila extramacrochaetae locus, an antagonist of proneural genes that, like these genes, encodes a helix-loop-helix protein

1990 • 387 citations

Patterning of the Drosophila nervous system: the achaete-scute gene complex

1992 • 384 citations

Acidic and basic fibroblast growth factors promote stable neurite outgrowth and neuronal differentiation in cultures of PC12 cells

1987 • 353 citations

An Id-related helix-loop-helix protein encoded by a growth factor-inducible gene.

1991 • 352 citations

Decapentaplegic: A gene complex affecting morphogenesis in Drosophila melanogaster

1982 • 345 citations

Diffusible factors in vertebrate embryonic induction

1992 • 327 citations

Intragenic pausing and anti-sense transcription within the murine c-myc locus.

1986 • 326 citations

The neural crest cell lineage problem: Neuropoiesis?

1989 • 315 citations

Reciprocal Regulation of Adipogenesis by Myc and C/EBPα

1992 • 296 citations

Genesis of the Drosophila peripheral nervous system

1989 • 289 citations

The Drosophila spitz gene encodes a putative EGF-like growth factor involved in dorsal-ventral axis formation and neurogenesis.

1992 • 278 citations

Closely related transcripts encoded by the neurogenic gene complex enhancer of split of Drosophila melanogaster.

1989 • 274 citations

The expression of three members of the achaete-scute gene complex correlates with neuroblast segregation in Drosophila

1987 • 272 citations

The effect of fibroblast growth factor on PC12 cells

1985 • 270 citations

The Drosophila extramacrochaetae protein antagonizes sequence-specific DNA binding by daughterless/achaete-scute protein complexes

1991 • 257 citations

Expression of achaete and scute genes in Drosophila imaginal discs and their function in sensory organ development.

1989 • 246 citations

The Drosophila hairy protein acts in both segmentation and bristle patterning and shows homology to N-myc.

1989 • 245 citations

Expression of a MyoD family member prefigures muscle pattern in Drosophila embryos.

1990 • 243 citations

Transcriptional activation by heterodimers of the achaete-scute and daughterless gene products of Drosophila.

1991 • 238 citations

deadpan, an essential pan-neural gene in Drosophila, encodes a helix-loop-helix protein similar to the hairy gene product.

1992 • 223 citations

Genetic and Molecular Bases of Neurogenesis in Drosophila Melanogaster

1991 • 152 citations

Ionic responses and growth stimulation induced by nerve growth factor and epidermal growth factor in rat pheochromocytoma (PC12) cells.

1983 • 150 citations

The molecular biology of the Notch locus and the fine tuning of differentiation in Drosophila

1988 • 148 citations

The induction of a neural-specific gene, SCG10, by nerve growth factor in PC12 cells is transcriptional, protein synthesis dependent, and glucocorticoid inhibitable

1988 • 148 citations

deadpan, an essential pan-neural gene encoding an HLH protein, acts as a denominator in Drosophila sex determination

1992 • 142 citations

Genes required for specifying cell fates in Drosophila embryonic sensory nervous system

1990 • 139 citations

Gene-dose titration analysis in the search of trans-regulatory genes in Drosophila.

1982 • 134 citations

Neural crest cell lineages

1981 • 129 citations

The achaete-scute complex is expressed in neurogenic regions of Drosophila embryos

1987 • 129 citations

The protein Id: a negative regulator of helix-loop-helix DNA binding proteins

1990 • 123 citations

Induction and repression of mammalian achaete-scute homologue (MASH) gene expression during neuronal differentiation of P19 embryonal carcinoma cells

1992 • 121 citations

Genetic regulation of theAchaete-scute complex ofDrosophila melanogaster

1984 • 118 citations

EGF homologous sequences encoded in the genome of Drosophila melanogaster, and their relation to neurogenic genes.

1987 • 116 citations

The role of the hairy gene during Drosophila morphogenesis: stripes in imaginal discs

1989 • 89 citations

Genetics of early neurogenesis in Drosophila melanogaster

1985 • 57 citations

Nerve growth factor-induced differentiation in PC-12 cells is blocked by fos oncogene.

1989 • 36 citations

A cell cycle analysis of growth-related genes expressed during T lymphocyte maturation.

1990 • 32 citations

Inhibition of PC-12 cell differentiation by the immediate early gene fra-1.

1990 • 24 citations

Role of Helix-Loop-Helix Proteins in Drosophila Neurogenesis

1990 • 18 citations

extramacrochaetae, a negative regulator of sensory organ development in Drosophila, defines a new class of helix-loop-helix proteins

1990 • 13 citations

Genetic And Molecular Bases Of Neurogenesis In Drosophila Melanogaster

1991 • 6 citations