Ca²⁺ activation of heart mitochondrial oxidative phosphorylation: role of the F₀/F₁-ATPase

Close Contacts with the Endoplasmic Reticulum as Determinants of Mitochondrial Ca ²⁺ Responses

1998 • 2,130 citations

THE ATP SYNTHASE—A SPLENDID MOLECULAR MACHINE

1997 • 1,934 citations

Purification and properties

1975 • 1,733 citations

Calculator programs for computing the composition of the solutions containing multiple metals and ligands used for experiments in skinned muscle cells.

1979 • 1,648 citations

RESPIRATORY ENZYMES IN OXIDATIVE PHOSPHORYLATION

1955 • 1,457 citations

The mitochondrial permeability transition in cell death: a common mechanism in necrosis, apoptosis and autophagy

1998 • 1,381 citations

Role of calcium ions in regulation of mammalian intramitochondrial metabolism

1990 • 1,369 citations

Microdomains with High Ca ²⁺ Close to IP ₃ -Sensitive Channels that Are Sensed by Neighboring Mitochondria

1993 • 1,167 citations

Decoding of cytosolic calcium oscillations in the mitochondria

1995 • 1,090 citations

Respiratory Enzymes in Oxidative Phosphorylation

1958 • 900 citations

Mitochondria Are Excitable Organelles Capable of Generating and Conveying Electrical and Calcium Signals

1997 • 739 citations

Mitochondrial calcium transport: physiological and pathological relevance

1994 • 702 citations

THE EFFECT OF ARSENATE ON AEROBIC PHOSPHORYLATION

1953 • 546 citations

The regulation of the matrix volume of mammalian mitochondria in vivo and in vitro and its role in the control of mitochondrial metabolism

1989 • 443 citations

The oxidation of citrate, isocitrate and cis-aconitate by isolated mitochondria

1964 • 395 citations

Relation Between Work and Phosphate Metabolite in the in Vivo Paced Mammalian Heart

1986 • 383 citations

Direct demonstration of a specific interaction between cyclophilin-D and the adenine nucleotide translocase confirms their role in the mitochondrial permeability transition

1998 • 381 citations

Control of mitochondrial ATP synthesis in the heart

1991 • 333 citations

Mitochondrial Calcium Uptake from Physiological-type Pulses of Calcium

1995 • 299 citations

Measurement of mitochondrial free Ca2+ concentration in living single rat cardiac myocytes

1991 • 277 citations

Intracellular calcium transients underlying the short‐term force‐interval relationship in ferret ventricular myocardium.

1986 • 277 citations

The molecular mechanism of action of the proton ionophore FCCP (carbonylcyanide p-trifluoromethoxyphenylhydrazone)

1983 • 254 citations

Kinetics of the firefly luciferase catalyzed reactions

1974 • 253 citations

Relation between phosphate metabolites and oxygen consumption of heart in vivo

1989 • 249 citations

Calcium uptake and membrane potential in mitochondria

1974 • 247 citations

Membrane potential and surface potential in mitochondria: Uptake and binding of lipophilic cations

1984 • 213 citations

Selective Loading of Rhod 2 into Mitochondria Shows Mitochondrial Ca2+Transients during the Contractile Cycle in Adult Rabbit Cardiac Myocytes

1997 • 191 citations

The Cycling of Calcium, Sodium, and Protons Across the Inner Membrane of Cardiac Mitochondria

1978 • 188 citations

Role of mitochondrial calcium transport in the control of substrate oxidation

1998 • 177 citations

The Ca2+ transport mechanisms of mitochondria and Ca2+ uptake from physiological-type Ca2+ transients

1998 • 165 citations

Untitled

1998 • 147 citations

The phosphorus/oxygen ratio of mitochondrial oxidative phosphorylation

1979 • 146 citations

CALCIUM IN CLOSE QUARTERS:Microdomain Feedback in Excitation-Contraction Coupling and Other Cell Biological Phenomena

1997 • 131 citations

Maximum oxidative phosphorylation capacity of the mammalian heart

1997 • 131 citations

ADP-arsenate. Formation by submitochondrial particles under phosphorylating conditions.

1981 • 121 citations

The Thermodynamic Description of Enzyme-Catalyzed Reactions

1973 • 114 citations

Control of mitochondrial ATP synthase in heart cells: inactive to active transitions caused by beating or positive inotropic agents

1990 • 113 citations

Dependence of cardiac mitochondrial pyruvate dehydrogenase activity on intramitochondrial free Ca2+ concentration

1988 • 110 citations

Effects of cardiac work on electrical potential gradient across mitochondrial membrane in perfused rat hearts

1993 • 107 citations

Chaotropic Agents and Increased Matrix Volume Enhance Binding of Mitochondrial Cyclophilin to the Inner Mitochondrial Membrane and Sensitize the Mitochondrial Permeability Transition to [Ca²⁺]

1996 • 105 citations

Uncoupling of respiratory-chain phosphorylation by arsenate

1967 • 100 citations

The role of mitochondrial Ca2+ transport and matrix Ca2+ in signal transduction in mammalian tissues

1990 • 99 citations

Mitochondrial free calcium transients during excitation‐contraction coupling in rabbit cardiac myocytes

1996 • 99 citations

Changes in mitochondrial calcium concentration during the cardiac contraction cycle

1993 • 94 citations

Influence of NAD-linked dehydrogenase activity on flux through oxidative phosphorylation

1990 • 91 citations

Changes in pyridine nucleotide levels alter oxygen consumption and extra-mitochondrial phosphates in isolated mitochondria: A 31P-NMR and NAD(P)H fluorescence study

1987 • 90 citations

Factors affecting the kinetics of light emission from crude and purified firefly luciferase

1979 • 85 citations

A second mechanism of respiratory control

1999 • 84 citations

Effects of afterload and heart rate on NAD(P)H redox state in the isolated rabbit heart

1993 • 83 citations

Spectroscopic Determination of Cytochrome c Oxidase Content in Tissues Containing Myoglobin or Hemoglobin

1996 • 80 citations

The calcium-binding ATPase inhibitor protein from bovine heart mitochondria. Purification and properties.

1988 • 71 citations

Contribution of the translocator of adenine nucleotides and the ATP synthase to the control of oxidative phosphorylation and arsenylation in liver mitochondria.

1985 • 69 citations

Effect of oligomycin on the arsenate and DNP stimulation of mitochondrial oxidations

1961 • 69 citations

Are/were mitochondria and chloroplasts microorganisms?

1970 • 65 citations

[48] Continuous measurement of adenosine triphosphate with firefly luciferase luminescence

1979 • 60 citations

Efficiency of energy conversion in model biological pumps

1983 • 59 citations

Correction for inner filter effects in turbid samples: fluorescence assays of mitochondrial NADH

1998 • 58 citations

Mitochondrial F1-ATPase activity of canine myocardium: effects of hypoxia and stimulation

1994 • 57 citations

Adenosine triphosphate: Continuous measurement in mitochondrial suspensions by firefly luciferase luminescence

1973 • 46 citations

Calcium-binding ATPase inhibitor protein of bovine heart mitochondria. Role in ATP synthesis and effect of calcium

1989 • 39 citations

Control of mitochondrial ATP synthase in rat cardiomyocytes: effects of thyroid hormone

1991 • 37 citations

Reversible modulation of the mitochondrial ATP synthase with energy demand in cultured rat cardiomyocytes

1989 • 36 citations

Insights into cellular energy metabolism from transgenic mice

1995 • 34 citations

NMR studies of renal phosphate metabolites in vivo: effects of hydration and dehydration

1988 • 28 citations

Parallel stimulation by Ca2+ of inotropism and pyruvate dehydrogenase in perfused heart

1984 • 27 citations

Energetic cost of activation processes during contraction of swine arterial smooth muscle

1997 • 25 citations

Nuclear magnetic resonance determination of flow, lactate, and phosphate metabolites during amphetamine stimulation of the rat brain

1990 • 24 citations

Inhibitor peptide of mitochondrial proton adenosine triphosphatase. Neutralization of its inhibitory action by calmodulin.

1984 • 19 citations

The mechanism of respiratory control in the in vivo heart

1989 • 19 citations

Intracellular calcium and high-energy phosphates in isolated cardiac myocytes

1990 • 18 citations

Ca2+-binding properties of a unique ATPase inhibitor protein isolated from mitochondria of bovine heart and rat skeletal muscle

1985 • 17 citations

Uncoupling of oxidative phosphorylation: different effects of lipophilic weak acids and electrogenic ionophores on the kinetics of ATP synthesis

1989 • 16 citations

Cation transport by mitochondria

1994 • 15 citations

Activation of Pyruvate Dehydrogenase Complex by Ca²⁺in Intact Heart, Cardiac Myocytes, and Cardiac Mitochondria

1989 • 14 citations

Intracellular calcium as a regulator of the mitochondrial ATP synthase in cultured cardiomyocytes

1990 • 13 citations

Distinct modulation of myocardial performance, energy metabolism, and [Ca2+]i transients by positive inotropic drugs in normal and severely failing hamster hearts

1995 • 12 citations

Factors affecting the reactivation of the mitochondrial adenosine 5′-triphosphatase and the release of ATPase inhibitor protein during and following the reenergization of mitochondria from ischemic cardiac muscle

1989 • 11 citations