Cell-Mediated DNA Transport Between Distant Inflammatory Sites Following Intradermal DNA Immunization in the Presence of Adjuvant

The Dendritic Cell System and its Role in Immunogenicity

1991 • 4,733 citations

Heterologous Protection Against Influenza by Injection of DNA Encoding a Viral Protein

1993 • 2,330 citations

DNA VACCINES

1997 • 977 citations

DNA–based immunization by in vivo transfection of dendritic cells

1996 • 849 citations

Migration and maturation of Langerhans cells in skin transplants and explants.

1990 • 663 citations

Predominant Role for Directly Transfected Dendritic Cells in Antigen Presentation to CD8+ T Cells after Gene Gun Immunization

1998 • 569 citations

Different T helper cell types and antibody isotypes generated by saline and gene gun DNA immunization.

1997 • 566 citations

Intradermal gene immunization: the possible role of DNA uptake in the induction of cellular immunity to viruses.

1994 • 550 citations

Evidence that cutaneous antigen-presenting cells migrate to regional lymph nodes during contact sensitization.

1990 • 543 citations

Gene vaccination with naked plasmid DNA: mechanism of CTL priming.

1996 • 494 citations

Gene vaccination: plasmid DNA is more than just a blueprint

1998 • 359 citations

Induction of cytotoxic T lymphocytes by intramuscular immunization with plasmid DNA is facilitated by bone marrow-derived cells.

1996 • 353 citations

Differential dependence on target site tissue for gene gun and intramuscular DNA immunizations.

1997 • 287 citations

Foreign (M13) DNA ingested by mice reaches peripheral leukocytes, spleen, and liver via the intestinal wall mucosa and can be covalently linked to mouse DNA

1997 • 283 citations

Detection of HIV-1 DNA and Messenger RNA in Individual Cells by PCR-Driven in Situ Hybridization and Flow Cytometry

1993 • 270 citations

DNA-mediated immunization to the hepatitis B surface antigen in mice: aspects of the humoral response mimic hepatitis B viral infection in humans.

1995 • 266 citations

The dominant role of bone marrow-derived cells in CTL induction following plasmid DNA immunization at different sites.

1997 • 257 citations

Specific Immune Induction Following DNA-Based Immunization Through In Vivo Transfection and Activation of Macrophages/Antigen-Presenting Cells

1998 • 223 citations

Immunization of non-human primates with DNA vaccines

1997 • 223 citations

A Role for Mac-1 (CDIIb/CD18) in Immune Complex–stimulated Neutrophil Function In Vivo: Mac-1 Deficiency Abrogates Sustained Fcγ Receptor–dependent Neutrophil Adhesion and Complement-dependent Proteinuria in Acute Glomerulonephritis

1997 • 215 citations

Expression of naked DNA in human, pig, and mouse skin.

1996 • 198 citations

Methylation of foreign DNA sequences in eukaryotic cells.

1980 • 190 citations

DNA immunization: Induction of higher avidity antibody and effect of route on T cell cytotoxicity

1997 • 155 citations

DNA vaccines

1997 • 149 citations

The alpha 4-integrin supports leukocyte rolling and adhesion in chronically inflamed postcapillary venules in vivo.

1996 • 148 citations

Plasmid DNA encoding transforming growth factor-beta1 suppresses chronic disease in a streptococcal cell wall-induced arthritis model.

1998 • 134 citations

Entry Into Afferent Lymphatics and Maturation In Situ of Migrating Murine Cutaneous Dendritic Cells

1998 • 113 citations

The immunologic properties of DNA.

1996 • 109 citations

Monocyte migration to arthritis in the rat utilizes both CD11/CD18 and very late activation antigen 4 integrin mechanisms.

1995 • 101 citations

The contribution of LFA-1 (CD11a/CD18) and MAC-1 (CD11b/CD18) to the in vivo migration of polymorphonuclear leucocytes to inflammatory reactions in the rat.

1992 • 98 citations

High expression of naked plasmid DNA in muscles of young rodents

1997 • 94 citations

DNA immunization can stimulate florid local inflammation, and the antiviral immunity induced varies depending on injection site

1997 • 58 citations

A model for keratinocyte gene therapy: preclinical and therapeutic considerations.

1996 • 25 citations

DNA Vaccines

1996 • 19 citations

Site-directed immunogenesis

1998 • 6 citations