A Role for Mac-1 (CDIIb/CD18) in Immune Complex–stimulated Neutrophil Function In Vivo: Mac-1 Deficiency Abrogates Sustained Fcγ Receptor–dependent Neutrophil Adhesion and Complement-dependent Proteinuria in Acute Glomerulonephritis

Structure and function of the leukocyte adhesion molecules CD11/CD18

1990 • 962 citations

Structure and function of the leukocyte adhesion molecules CD11/CD18

1990 • 785 citations

A Novel Role for the β2 Integrin CD11b/CD18 in Neutrophil Apoptosis: A Homeostatic Mechanism in Inflammation

1996 • 645 citations

Leukocytosis and resistance to septic shock in intercellular adhesion molecule 1-deficient mice.

1994 • 492 citations

Adhesion through L-selectin requires a threshold hydrodynamic shear

1996 • 456 citations

Threshold Levels of Fluid Shear Promote Leukocyte Adhesion through Selectins (CD62L,P,E)

1997 • 349 citations

CR3 (Mac-1, alpha M beta 2, CD11b/CD18) and Fc gamma RIII cooperate in generation of a neutrophil respiratory burst: requirement for Fc gamma RIII and tyrosine phosphorylation.

1994 • 332 citations

Inhibition of phagocytosis of complement C3- or immunoglobulin G-coated particles and of C3bi binding by monoclonal antibodies to a monocyte-granulocyte membrane glycoprotein (Mol).

1983 • 303 citations

LFA-1 is sufficient in mediating neutrophil emigration in Mac-1-deficient mice.

1997 • 291 citations

Requirements for leukocyte adhesion molecules in nephrotoxic nephritis.

1993 • 197 citations

Cocapping of the leukoadhesin molecules complement receptor type 3 and lymphocyte function-associated antigen-1 with Fc gamma receptor III on human neutrophils. Possible role of lectin-like interactions.

1993 • 192 citations

Molecular definition of the bovine granulocytopathy syndrome: Identification of deficiency of the Mac-1 (CD11b/CD18) glycoprotein

1990 • 192 citations

An immobile subset of plasma membrane CD11b/CD18 (Mac-1) is involved in phagocytosis of targets recognized by multiple receptors.

1989 • 141 citations

Mechanism of inhibition of immunoglobulin G-mediated phagocytosis by monoclonal antibodies that recognize the Mac-1 antigen.

1988 • 125 citations

Reconstitution of antibody-dependent phagocytosis in fibroblasts expressing Fc gamma receptor IIIB and the complement receptor type 3.

1994 • 111 citations

Neutrophils, monocytes, and lymphocytes bind to cytokine-activated kidney glomerular endothelial cells through L-selectin (LAM-1) in vitro.

1992 • 98 citations

Complement receptor 3 (CR3, Mac-1, integrin alpha M beta 2, CD11b/CD18) is required for tyrosine phosphorylation of paxillin in adherent and nonadherent neutrophils.

1994 • 89 citations

Immune complex-stimulated neutrophil LTB4 production is dependent on beta 2 integrins.

1993 • 88 citations

Acute passive anti-glomerular basement membrane nephritis in P-selectin-deficient mice

1996 • 86 citations

Antiglomerular basement membrane nephritis in beige mice. Deficiency of leukocytic neutral proteinases prevents the induction of albuminuria in the heterologous phase.

1989 • 86 citations

Neutrophil fate in experimental glomerular capillary injury in the rat. Emigration exceeds in situ clearance by apoptosis.

1997 • 85 citations

A crucial role for beta 2 integrin in the activation of eosinophils stimulated by IgG.

1995 • 84 citations

Determinants of immune complex-mediated glomerulonephritis

1988 • 80 citations

Granulocyte activation via a binding site near the C-terminal region of complement receptor type 3 alpha-chain (CD11b) potentially involved in intramembrane complex formation with glycosylphosphatidylinositol-anchored Fc gamma RIIIB (CD16) molecules.

1995 • 78 citations

CR3 (alphaM beta2; CD11b/CD18) restores IgG-dependent phagocytosis in transfectants expressing a phagocytosis-defective Fc gammaRIIA (CD32) tail-minus mutant.

1996 • 63 citations

Anti-GBM nephritis in the mouse: Role of granulocytes in the heterologous phase

1990 • 63 citations

Glomerular lesions in nonobese diabetic mouse: before and after the onset of hyperglycemia.

1990 • 62 citations

Surface-bound immune complexes trigger transmembrane proximity between complement receptor type 3 and the neutrophil's cortical microfilaments.

1992 • 40 citations

Involvement of CD11b/CD18 in enhanced neutrophil adhesion by Fcγ receptor stimulation

1994 • 32 citations

Attenuation of immune-mediated glomerulonephritis with an anti-CD11b monoclonal antibody

1993 • 31 citations

Antiglomerular basement membrane nephritis in the mouse. Study on the role of complement in the heterologous phase.

1988 • 27 citations