Specific association of the proto-oncogene product pp60c-src with an intracellular organelle, the PC12 synaptic vesicle

Phase separation of integral membrane proteins in Triton X-114 solution.

1981 • 3,366 citations

Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in mice

1991 • 2,028 citations

DNA related to the transforming gene(s) of avian sarcoma viruses is present in normal avian DNA

1976 • 1,290 citations

Protein p38: an integral membrane protein specific for small vesicles of neurons and neuroendocrine cells.

1986 • 671 citations

Proteins of synaptic vesicles involved in exocytosis and membrane recycling

1991 • 523 citations

Isolation of monoclonal antibodies that recognize the transforming proteins of avian sarcoma viruses

1983 • 518 citations

Identification, by a monoclonal antibody, of a 53-kD protein associated with a tubulo-vesicular compartment at the cis-side of the Golgi apparatus.

1988 • 488 citations

rab3 is a small GTP-binding protein exclusively localized to synaptic vesicles.

1990 • 486 citations

A short sequence in the p60src N terminus is required for p60src myristylation and membrane association and for cell transformation.

1984 • 447 citations

A small GTP-binding protein dissociates from synaptic vesicles during exocytosis

1991 • 441 citations

Mutation of NH2-terminal glycine of p60src prevents both myristoylation and morphological transformation.

1985 • 386 citations

Neurones express high levels of a structurally modified, activated form of pp60c-src

1985 • 372 citations

Specific proto-oncogenic tyrosine kinases of src family are enriched in cell-to-cell adherens junctions where the level of tyrosine phosphorylation is elevated.

1991 • 310 citations

Characterization of synapsin I binding to small synaptic vesicles.

1986 • 304 citations

The protein encoded by the transforming gene of avian sarcoma virus (pp60src) and a homologous protein in normal cells (pp60proto-src) are associated with the plasma membrane.

1980 • 298 citations

Neural Tissues Express High Levels of the Cellular src Gene Product pp60^c-src

1983 • 288 citations

The neural network underlying locomotion in lamprey-synaptic and cellular mechanisms

1991 • 203 citations

c-src gene product in developing rat brain is enriched in nerve growth cone membranes.

1988 • 193 citations

Biogenesis of synaptic vesicle-like structures in a pheochromocytoma cell line PC-12.

1990 • 187 citations

The absence of myristic acid decreases membrane binding of p60src but does not affect tyrosine protein kinase activity

1986 • 174 citations

The Cellular src Gene Product Regulates Junctional Cell-to-Cell Communication

1988 • 169 citations

Localization and subcellular distribution of smg p25A, a ras p21-like GTP-binding protein, in rat brain.

1990 • 163 citations

Identification of a 32K plasma membrane protein that binds to the myristylated amino-terminal sequence of p60v-src

1990 • 162 citations

Synaptophysin is targeted to similar microvesicles in CHO and PC12 cells.

1989 • 157 citations

A Short Sequence in the p60^src N Terminus Is Required for p60^src Myristylation and Membrane Association and for Cell Transformation

1984 • 149 citations

Specific and saturable binding of pp60v-src to plasma membranes: Evidence for a myristyl-src receptor

1989 • 137 citations

Highly specific antibody to Rous sarcoma virus src gene product recognizes a novel population of pp60v-src and pp60c-src molecules.

1985 • 133 citations

Redistribution of synaptophysin and synapsin I during alpha-latrotoxin-induced release of neurotransmitter at the neuromuscular junction.

1990 • 122 citations

Immunolocalization of the cellular src protein in interphase and mitotic NIH c-src overexpresser cells.

1990 • 120 citations

The src protein contains multiple domains for specific attachment to membranes.

1990 • 112 citations

p60c-src activity detected in the chromaffin granule membrane

1986 • 109 citations

Protein Tyrosine Kinase Activity and Its Endogenous Substrates in Rat Brain: A Subcellular and Regional Survey

1988 • 108 citations

Synaptophysin: a substrate for the protein tyrosine kinase pp60c-src in intact synaptic vesicles.

1990 • 106 citations

Processing of p60v-src to its myristylated membrane-bound form.

1985 • 102 citations

Changes in amino-terminal sequences of pp60src lead to decreased membrane association and decreased in vivo tumorigenicity

1982 • 97 citations

Translocation of synapsin I in response to depolarization of isolated nerve terminals.

1989 • 94 citations

Fractionation of synaptophysin‐containing vesicles from rat brain and cultured PC12 pheochromocytoma cells

1988 • 73 citations

p60c-src is complexed with a cellular protein in subcellular compartments involved in exocytosis.

1988 • 69 citations

Polyomavirus Middle T Antigen Downregulates Junctional Cell-to-Cell Communication

1987 • 66 citations

Processing of p60^v-src to Its Myristylated Membrane-Bound Form

1985 • 40 citations

Intracellular localization of pp60c-src in human platelets.

1990 • 33 citations

The src Protein Contains Multiple Domains for Specific Attachment to Membranes

1990 • 30 citations

Involvement of the membrane cytoskeletal proteins and the src gene product in growth cone adhesion and movement

1990 • 16 citations

Identification of platelet membrane proteins that interact with amino-terminal peptides of pp60c-src.

1991 • 12 citations