Immunolocalization of the cellular src protein in interphase and mitotic NIH c-src overexpresser cells.

Transforming gene product of Rous sarcoma virus phosphorylates tyrosine

1980 • 2,387 citations

Focal Adhesions: Transmembrane Junctions Between the Extracellular Matrix and the Cytoskeleton

1988 • 2,137 citations

Complementation used to clone a human homologue of the fission yeast cell cycle control gene cdc2

1987 • 1,153 citations

Purified maturation-promoting factor contains the product of a Xenopus homolog of the fission yeast cell cycle control gene cdc2+

1988 • 885 citations

The Xenopus cdc2 protein is a component of MPF, a cytoplasmic regulator of mitosis

1988 • 829 citations

Isolation of monoclonal antibodies that recognize the transforming proteins of avian sarcoma viruses

1983 • 518 citations

Reversible tyrosine phosphorylation of cdc2: Dephosphorylation accompanies activation during entry into mitosis

1989 • 453 citations

A short sequence in the p60src N terminus is required for p60src myristylation and membrane association and for cell transformation.

1984 • 447 citations

Fluorescence staining of the actin cytoskeleton in living cells with 7-nitrobenz-2-oxa-1,3-diazole-phallacidin.

1980 • 441 citations

The cdc2 kinase is a nuclear protein that is essential for mitosis in mammalian cells

1989 • 439 citations

Movement of internalized ligand–receptor complexes along a continuous endosomal reticulum

1990 • 428 citations

Antibodies to the Golgi complex and the rough endoplasmic reticulum.

1982 • 418 citations

Cell Transformation by the Viral src Oncogene

1987 • 405 citations

Mutation of NH2-terminal glycine of p60src prevents both myristoylation and morphological transformation.

1985 • 386 citations

p34cdc2 is located in both nucleus and cytoplasm; part is centrosomally associated at G2/M and enters vesicles at anaphase.

1989 • 376 citations

Phosphorylation of Connexin43 Gap Junction Protein in Uninfected and Rous Sarcoma Virus-Transformed Mammalian Fibroblasts

1990 • 352 citations

Adhesion plaques of Rous sarcoma virus-transformed cells contain the src gene product.

1980 • 334 citations

Purified maturation promoting factor phosphorylates pp60c-src at the sites phosphorylated during fibroblast mitosis

1989 • 319 citations

Cytoplasmic microtubules in normal and transformed cells in culture: analysis by tubulin antibody immunofluorescence.

1975 • 307 citations

The protein encoded by the transforming gene of avian sarcoma virus (pp60src) and a homologous protein in normal cells (pp60proto-src) are associated with the plasma membrane.

1980 • 298 citations

Altered distributions of the cytoskeletal proteins vinculin and alpha-actinin in cultured fibroblasts transformed by Rous sarcoma virus.

1980 • 296 citations

Human cdc2 protein kinase is a major cell-cycle regulated tyrosine kinase substrate

1988 • 285 citations

Localization of the ASV src gene product to the plasma membrane of transformed cells by electron microscopic immunocytochemistry

1979 • 276 citations

Changes in cellular glycoproteins after transformation: identification of specific glycoproteins and antigens in sodium dodecyl sulfate gels.

1976 • 269 citations

A monoclonal antibody against a 135-K Golgi membrane protein.

1982 • 262 citations

Subcellular compartmentalization of saccharide moieties in cultured normal and malignant cells.

1980 • 260 citations

Altered phosphorylation and activation of PP60c-src during fibroblast mitosis

1988 • 249 citations

Mitosis-specific phosphorylation of p60c-src by p34cdc2-associated protein kinase

1989 • 239 citations

Rous sarcoma virus variants that carry the cellular src gene instead of the viral src gene cannot transform chicken embryo fibroblasts.

1984 • 239 citations

Lipid recycling between the plasma membrane and intracellular compartments: transport and metabolism of fluorescent sphingomyelin analogues in cultured fibroblasts.

1989 • 221 citations

Expression of v-src and chicken c-src in rat cells demonstrates qualitative differences between pp60v-src and pp60c-src

1984 • 194 citations

c-src gene product in developing rat brain is enriched in nerve growth cone membranes.

1988 • 193 citations

Antibody-induced linkages of plasma membrane proteins to intracellular actomyosin-containing filaments in cultured fibroblasts.

1977 • 193 citations

Surface functions during mitosis I: Phagocytosis, pinocytosis and mobility of surface-bound ConA

1978 • 185 citations

Overexpressed pp60c-src can induce focus formation without complete transformation of NIH 3T3 cells.

1985 • 171 citations

The Cellular src Gene Product Regulates Junctional Cell-to-Cell Communication

1988 • 169 citations

Association of the src gene product of Rous sarcoma virus with cytoskeletal structures of chicken embryo fibroblasts.

1980 • 169 citations

Monoclonal antibodies to Rous sarcoma virus pp60src react with enzymatically active cellular pp60src of avian and mammalian origin

1984 • 163 citations

Association of p60src with Triton X-100-resistant cellular structure correlates with morphological transformation.

1987 • 163 citations

Interaction Between the Rous Sarcoma Virus Transforming Protein and Two Cellular Phosphoproteins: Analysis of the Turnover and Distribution of This Complex

1983 • 162 citations

Overexpression of the c-src protein does not induce transformation of NIH 3T3 cells.

1984 • 161 citations

A Short Sequence in the p60^src N Terminus Is Required for p60^src Myristylation and Membrane Association and for Cell Transformation

1984 • 149 citations

Highly specific antibody to Rous sarcoma virus src gene product recognizes a novel population of pp60v-src and pp60c-src molecules.

1985 • 133 citations

Concanavalin-A-induced transmembrane linkage of concanavalin A surface receptors to intracellular myosin-containing filaments.

1976 • 119 citations

Immunofluorescent localization of the transforming protein of Rous sarcoma virus with antibodies against a synthetic src peptide.

1982 • 119 citations

The src protein contains multiple domains for specific attachment to membranes.

1990 • 112 citations

Nonmitogenic Morphoregulatory Action of pp6O^v-src on Multicellular Epithelial Structures

1987 • 110 citations

p60c-src activity detected in the chromaffin granule membrane

1986 • 109 citations

Synaptophysin: a substrate for the protein tyrosine kinase pp60c-src in intact synaptic vesicles.

1990 • 106 citations

Microtubule and microfilament rearrangements during capping of concanavalin A receptors on cultured ovarian granulosa cells.

1977 • 103 citations

Potential role of the src gene product in inhibition of gap-junctional communication in NIH/3T3 cells.

1985 • 93 citations

Differences in intracellular location of pp60src in rat and chicken cells transformed by Rous sarcoma virus.

1980 • 69 citations

p60c-src is complexed with a cellular protein in subcellular compartments involved in exocytosis.

1988 • 69 citations

High pp60c-src level in human platelet dense bodies

1989 • 64 citations

Elevated expression of pp60c-src alters a selective morphogenetic property of epithelial cells in vitro without a mitogenic effect.

1988 • 52 citations

Overexpressed pp60^c-src Can Induce Focus Formation Without Complete Transformation of NIH 3T3 Cells

1985 • 51 citations

Membrane boundaries involved in the uptake and intracellular processing of cell surface receptors

1986 • 50 citations

Cellular src gene product detected in the freshwater sponge Spongilla lacustris.

1984 • 39 citations

Localization of pp60c- in growth cone of PC12 cell

1988 • 35 citations

pp60c-src has less affinity for the detergent-insoluble cellular matrix than do pp60v-src and other viral protein-tyrosine kinases

1987 • 35 citations

Localization of conserved and nonconserved epitopes within the Rous sarcoma virus-encoded src protein

1986 • 34 citations

Intracellular localization of pp60c-src in human platelets.

1990 • 33 citations

Intracellular localisation and expression of mammalian CDC2 protein during myogenic differentiation

1989 • 33 citations

pp60^c‐src is a substrate for phosphorylation when cells are stimulated to enter cycle

1984 • 30 citations

The src Protein Contains Multiple Domains for Specific Attachment to Membranes

1990 • 30 citations

A mitotic inducer matures

1988 • 15 citations

Cellular src Gene Product Detected in the Freshwater Sponge Spongilla lacustris

1984 • 9 citations

Elevated Expression of pp60^c-src Alters a Selective Morphogenetic Property of Epithelial Cells In Vitro without a Mitogenic Effect

1988 • 9 citations