Sense and antisense modification of glial alpha B-crystallin production results in alterations of stress fiber formation and thermoresistance.

A modification of the Lowry procedure to simplify protein determination in membrane and lipoprotein samples

1978 • 6,494 citations

Transformation of mammalian cells to antibiotic resistance with a bacterial gene under control of the SV40 early region promoter.

1982 • 2,753 citations

Alpha-crystallin can function as a molecular chaperone.

1992 • 1,822 citations

Differentiated Rat Glial Cell Strain in Tissue Culture

1968 • 1,480 citations

Small heat shock proteins are molecular chaperones.

1993 • 1,376 citations

Heat shock resistance conferred by expression of the human HSP27 gene in rodent cells.

1989 • 699 citations

Regulation of Simian Virus 40 Transcription: Sensitive Analysis of the RNA Species Present Early in Infections by Virus or Viral DNA

1979 • 623 citations

αB-crystallin is expressed in non-lenticular tissues and accumulates in Alexander's disease brain

1989 • 546 citations

αB subunit of lens-specific protein α-crystallin is present in other ocular and non-ocular tissues

1989 • 538 citations

Alpha B-crystallin is a small heat shock protein.

1991 • 526 citations

Induction of Chinese hamster HSP27 gene expression in mouse cells confers resistance to heat shock. HSP27 stabilization of the microfilament organization.

1993 • 494 citations

The Vertebrate Eye Lens

1977 • 449 citations

A 25-kD inhibitor of actin polymerization is a low molecular mass heat shock protein.

1991 • 445 citations

Expression of the murine alpha B-crystallin gene is not restricted to the lens.

1989 • 377 citations

Structural and functional similarities of bovine alpha-crystallin and mouse small heat-shock protein. A family of chaperones.

1993 • 375 citations

Cellular distribution of alpha B-crystallin in non-lenticular tissues.

1990 • 295 citations

Accumulation of alpha B-crystallin in central nervous system glia and neurons in pathologic conditions.

1992 • 259 citations

The dynamic state of heat shock proteins in chicken embryo fibroblasts.

1986 • 227 citations

Immunoreactive αA crystallin in rat non-lenticular tissues detected with a sensitive immunoassay method

1991 • 220 citations

Tissue distribution and developmental profiles of immunoreactive αB crystallin in the rat determined with a sensitive immunoassay system

1991 • 193 citations

Hypertonic stress induces αB-crystallin expression

1992 • 187 citations

Copurification of small heat shock protein with alpha B crystallin from human skeletal muscle.

1992 • 184 citations

Domain structure and evolution in α‐crystallins and small heat‐shock proteins

1985 • 180 citations

Alpha B-crystallin and 27-kd heat shock protein are regulated by stress conditions in the central nervous system and accumulate in Rosenthal fibers.

1993 • 158 citations

Heat shock protein 27 and alpha B-crystallin can form a complex, which dissociates by heat shock.

1992 • 151 citations

Properties of human malignant glioma cells in vitro.

1978 • 149 citations

Antisense inhibition of glial S100 beta production results in alterations in cell morphology, cytoskeletal organization, and cell proliferation.

1990 • 136 citations

c-erbA Protooncogenes Mediate Thyroid Hormone-Dependent and Independent Regulation of the Rat Growth Hormone and Prolactin Genes

1988 • 133 citations

αB-Crystallin Expression in Mouse NIH 3T3 Fibroblasts: Glucocorticoid Responsiveness and Involvement in Thermal Protection

1993 • 126 citations

Coordinate and independent regulation of αB‐crystallin and HSP27 expression in response to physiological stress

1994 • 119 citations

Characterization of an inhibitor of actin polymerization in vinculin‐rich fraction of turkey gizzard smooth muscle

1988 • 117 citations

Physiological and Pathological Changes in Levels of the Two Small Stress Proteins, HSP27 and ∝B Crystallin, in Rat Hindlimb Muscles1

1993 • 113 citations

Rapid loss of stress fibers in Chinese hamster ovary cells after hyperthermia.

1985 • 92 citations

αB-Crystallin in Skeletal Muscle: Purification and Localization1

1991 • 90 citations

Small heat shock proteins of Drosophila associate with the cytoskeleton.

1986 • 88 citations

Ultrastructural localization of aA-crystallin to the bovine lens fiber cell cytoskeleton

1991 • 83 citations

Cardiac alpha-crystallin

1990 • 79 citations

Preferential expression of αB-crystallin in astrocytic elements of neuroectodermal tumors

1991 • 70 citations

[46] Multiple antigenic peptide method for producing antipeptide site-specific antibodies

1989 • 66 citations

Cardiac alpha-crystallin

1990 • 62 citations

Multiple mRNAs of rat brain alpha-crystallin B chain result from alternative transcriptional initiation.

1990 • 59 citations

Early changes of αB-crystallin mRNA in rat skeletal muscle to mechanical tension and denervation

1991 • 56 citations

Association of α-crystallin with actin in cultured lens cells

1984 • 51 citations

Binding of actin to lens alpha crystallins

1992 • 43 citations

Interaction of Crystallins with the Cytoskeletal–Plasma Membrane Complex of the Bovine Lens

1984 • 42 citations

The effect of hypertonicity on aldose reductase, alpha B-crystallin, and organic osmolytes in the retinal pigment epithelium.

1993 • 40 citations

Immunohistochemical demonstration of alphaB-crystallin in hamartomas of tuberous sclerosis.

1991 • 38 citations

Association of crystallins with the plasma membrane

1982 • 36 citations

Is the cytoskeleton-plasma membrane complex involved in lens protein biosynthesis?

1979 • 19 citations

Opposite Effects of Cyclic AMP and Cell Density on Expression of αB-Crystallin and Glial Fibrillary Acidic Protein in C-6 Glioma Cells

1991 • 4 citations