The effect of hypertonicity on aldose reductase, alpha B-crystallin, and organic osmolytes in the retinal pigment epithelium.

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

Living with Water Stress: Evolution of Osmolyte Systems

1982 • 3,735 citations

Basic Methods in Molecular Biology

1986 • 3,284 citations

αB-crystallin is expressed in non-lenticular tissues and accumulates in Alexander's disease brain

1989 • 546 citations

Predominant osmotically active organic solutes in rat and rabbit renal medullas.

1986 • 382 citations

Expression of the murine alpha B-crystallin gene is not restricted to the lens.

1989 • 377 citations

Cellular distribution of alpha B-crystallin in non-lenticular tissues.

1990 • 295 citations

Induction of aldose reductase and sorbitol in renal inner medullary cells by elevated extracellular NaCl.

1987 • 173 citations

A thirty year journey in the polyol pathway

1990 • 166 citations

Molecular cloning of cDNA coding for kidney aldose reductase

1989 • 149 citations

Role of organic osmolytes in adaptation of renal cells to high osmolality

1991 • 140 citations

αB Crystallin Accumulation Is a Specific Response to Ha-ras and v-mos Oncogene Expression in Mouse NIH 3T3 Fibroblasts

1991 • 95 citations

Cardiac alpha-crystallin

1990 • 79 citations

Role of aldose reductase and sorbitol in maintaining the medullary intracellular milieu

1988 • 78 citations

Characterization and purification of a mammalian osmoregulatory protein, aldose reductase, induced in renal medullary cells by high extracellular NaCl.

1987 • 77 citations

Induction of aldose reductase expression in rat kidney mesangial cells and Chinese hamster ovary cells under hypertonic conditions

1990 • 56 citations

The effects of xylose on the isolated lens.

1974 • 52 citations

INOSITOL CHANGES IN NERVE AND LENS OF GALACTOSE FED RATS¹

1968 • 51 citations

Immunohistochemical localization for aldose reductase in diabetic lenses.

1987 • 46 citations

Increase in aldose reductase mRNA in dog lens epithelial cells under hypertonic conditions

1990 • 34 citations

Feedback inhibition of aldose reductase gene expression in rat renal medulla. Galactitol accumulation reduces enzyme mRNA levels and depletes cellular inositol content.

1990 • 29 citations

Transport of organic molecules in the lens

1973 • 29 citations

Study of crystallin expression in human lens epithelial cells during differentiation in culture and in non-lenticular tissues

1991 • 21 citations

Study of the polyol pathway and cell permeability changes in human lens and retinal pigment epithelium in tissue culture.

1992 • 20 citations

Osmotic Stress Induces Aldose Reductase in Glomerular Endothelial Cells

1990 • 19 citations

Aldose reductase mRNA is an epithelial cell-specific gene transcript in both normal and cataractous rat lens.

1990 • 19 citations

The Efficacy of Aldose Reductase Inhibitors on Polyol Accumulation in Human Lens and Retinal Pigment Epithelium in Tissue Culture

1992 • 18 citations

Aldose Reductase Messenger RNA in the Lens Epithelium in vivo: Effects of Diabetes Mellitus and Galactosaemia

1990 • 14 citations

Induction of the enzyme aldose reductase in a lens epithelial cell line from a transgenic mouse

1990 • 14 citations

Aldose reductase in early streptozotocin-induced diabetic rat lens.

1989 • 4 citations