Short telomeres are a risk factor for idiopathic pulmonary fibrosis

Telomeres shorten during ageing of human fibroblasts

1990 • 5,530 citations

American Thoracic Society/European Respiratory Society International Multidisciplinary Consensus Classification of the Idiopathic Interstitial Pneumonias

2002 • 3,947 citations

Identification of a specific telomere terminal transferase activity in tetrahymena extracts

1985 • 3,331 citations

A DNA damage checkpoint response in telomere-initiated senescence

2003 • 2,600 citations

Telomerase Catalytic Subunit Homologs from Fission Yeast and Human

1997 • 2,256 citations

Telomere Shortening and Tumor Formation by Mouse Cells Lacking Telomerase RNA

1997 • 2,086 citations

Essential role of mouse telomerase in highly proliferative organs

1998 • 1,256 citations

Telomerase Mutations in Families with Idiopathic Pulmonary Fibrosis

2007 • 1,249 citations

A telomerase component is defective in the human disease dyskeratosis congenita

1999 • 1,135 citations

The telomere terminal transferase of tetrahymena is a ribonucleoprotein enzyme with two kinds of primer specificity

1987 • 1,127 citations

The RNA component of telomerase is mutated in autosomal dominant dyskeratosis congenita

2001 • 955 citations

X-linked dyskeratosis congenita is caused by mutations in a highly conserved gene with putative nucleolar functions

1998 • 935 citations

Adult-onset pulmonary fibrosis caused by mutations in telomerase

2007 • 826 citations

Mutations inTERT,the Gene for Telomerase Reverse Transcriptase, in Aplastic Anemia

2005 • 706 citations

Heterozygosity for a Surfactant Protein C Gene Mutation Associated with Usual Interstitial Pneumonitis and Cellular Nonspecific Interstitial Pneumonitis in One Kindred

2002 • 635 citations

Secondary Structure of Vertebrate Telomerase RNA

2000 • 594 citations

Dyskeratosis congenita in all its forms

2000 • 552 citations

Disease anticipation is associated with progressive telomere shortening in families with dyskeratosis congenita due to mutations in TERC

2004 • 451 citations

Haploinsufficiency of t e lomerase reverse transcriptase leads to anticipation in autosomal dominant dyskeratosis congenita

2005 • 445 citations

Flow cytometry and FISH to measure the average length of telomeres (flow FISH)

2006 • 407 citations

Clinical and Pathologic Features of Familial Interstitial Pneumonia

2005 • 406 citations

Inhibition of Experimental Liver Cirrhosis in Mice by Telomerase Gene Delivery

2000 • 402 citations

TINF2, a Component of the Shelterin Telomere Protection Complex, Is Mutated in Dyskeratosis Congenita

2008 • 395 citations

Very short telomere length by flow fluorescence in situ hybridization identifies patients with dyskeratosis congenita

2007 • 331 citations

Telomere length homeostasis requires that telomerase levels are limiting

2006 • 309 citations

Mutations of the human telomerase RNA gene (TERC) in aplastic anemia and myelodysplastic syndrome

2003 • 306 citations

Genetic heterogeneity in autosomal recessive dyskeratosis congenita with one subtype due to mutations in the telomerase-associated protein NOP10

2007 • 304 citations

Short Telomeres, even in the Presence of Telomerase, Limit Tissue Renewal Capacity

2005 • 288 citations

Telomere Length Assessment in Human Archival Tissues

2002 • 218 citations

Dyskeratosis congenita: Advances in the understanding of the telomerase defect and the role of stem cell transplantation

2007 • 112 citations

Pulmonary fibrosis in families.

2003 • 87 citations

Structure and Function of the Smallest Vertebrate Telomerase RNA from Teleost Fish

2007 • 82 citations

Complex inheritance pattern of dyskeratosis congenita in two families with 2 different mutations in the telomerase reverse transcriptase gene

2007 • 59 citations

A disease of premature ageing

2001 • 48 citations

Human Telomerase RNA Template Sequence Is a Determinant of Telomere Repeat Extension Rate

2005 • 32 citations