Identification of the β cell antigen targeted by a prevalent population of pathogenic CD8⁺T cells in autoimmune diabetes

SYFPEITHI: database for MHC ligands and peptide motifs

1999 • 2,307 citations

Identification of the 64K autoantigen in insulin-dependent diabetes as the GABA-synthesizing enzyme glutamic acid decarboxylase

1990 • 1,955 citations

Scheme for ranking potential HLA-A2 binding peptides based on independent binding of individual peptide side-chains.

1994 • 1,400 citations

Insulin-Dependent Diabetes Mellitus

1996 • 1,171 citations

Insulin Antibodies in Insulin-Dependent Diabetics Before Insulin Treatment

1983 • 1,078 citations

Identification of an MHC class I-restricted autoantigen in type 1 diabetes by screening an organ-specific cDNA library

1999 • 442 citations

Detection of rare antigen-presenting cells by the lacZ T-cell activation assay suggests an expression cloning strategy for T-cell antigens.

1992 • 407 citations

Prediction of MHC class I binding peptides using profile motifs

2002 • 362 citations

Spontaneous Autoimmune Diabetes in Monoclonal T Cell Nonobese Diabetic Mice

1997 • 359 citations

Genetics of type 1 diabetes mellitus

2002 • 354 citations

Progression of autoimmune diabetes driven by avidity maturation of a T-cell population

2000 • 344 citations

Subfemtomole MS and MS/MS Peptide Sequence Analysis Using Nano-HPLC Micro-ESI Fourier Transform Ion Cyclotron Resonance Mass Spectrometry

2000 • 284 citations

NIT-1, a Pancreatic β-Cell Line Established From a Transgenic NOD/Lt Mouse

1991 • 254 citations

Prediction of spontaneous autoimmune diabetes in NOD mice by quantification of autoreactive T cells in peripheral blood

2003 • 210 citations

Autoreactive CD8 T Cells in Organ-Specific Autoimmunity

2002 • 204 citations

Major histocompatibility complex class I-restricted T cells are required for all but the end stages of diabetes development in nonobese diabetic mice and use a prevalent T cell receptor α chain gene rearrangement

1998 • 179 citations

Evidence for the role of CD8+ cytotoxic T cells in the destruction of pancreatic beta-cells in nonobese diabetic mice.

1994 • 157 citations

Prevalent CD8⁺T cell response against one peptide/MHC complex in autoimmune diabetes

1999 • 153 citations

Cutting Edge: The HLA-A*0101-Restricted HY Minor Histocompatibility Antigen Originates fromDFFRYand Contains a Cysteinylated Cysteine Residue as Identified by a Novel Mass Spectrometric Technique

1999 • 150 citations

Cloning and Expression of IDDM-Specific Human Autoantigens

1992 • 118 citations

Genes and Cellular Requirements for Autoimmune Diabetes Susceptibility in Nonobese Diabetic Mice

2001 • 117 citations

Molecular cloning of a pancreatic islet-specific glucose-6-phosphatase catalytic subunit-related protein.

1999 • 110 citations

Beta-cell-cytotoxic CD8+ T cells from nonobese diabetic mice use highly homologous T cell receptor alpha-chain CDR3 sequences.

1995 • 93 citations

Cloning and Characterization of the Human and Rat Islet-specific Glucose-6-phosphatase Catalytic Subunit-related Protein (IGRP) Genes

2001 • 82 citations

Expansion of the Antigenic Repertoire of a Single T Cell Receptor upon T Cell Activation

2001 • 70 citations

Analysis of structure and function relationships of an autoantigenic peptide of insulin bound to H-2K^dthat stimulates CD8 T cells in insulin-dependent diabetes mellitus

2002 • 61 citations

Melan-A/MART-1-specific CD8 T cells: from thymus to tumor

2002 • 60 citations

During the Early Prediabetic Period in NOD Mice, the Pathogenic CD8+ T-Cell Population Comprises Multiple Antigenic Specificities

2002 • 41 citations

Autoreactive Diabetogenic T-Cells in NOD Mice Can Efficiently Expand From a Greatly Reduced Precursor Pool

2001 • 40 citations