Granulocyte-Macrophage Colony-Stimulating Factor Gene-Modified Autologous Tumor Vaccines in Non-Small-Cell Lung Cancer

Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony-stimulating factor stimulates potent, specific, and long-lasting anti-tumor immunity.

1993 • 2,828 citations

Chemotherapy in non-small cell lung cancer: a meta-analysis using updated data on individual patients from 52 randomised clinical trials

1995 • 2,804 citations

Chemotherapy in non-small cell lung cancer: A meta-analysis using updated data on individual patients from 52 randomised clinical trials

1996 • 2,541 citations

HCAR and MCAR: The human and mouse cellular receptors for subgroup C adenoviruses and group B coxsackieviruses

1997 • 1,212 citations

Construction of adenovirus vectors through Cre-lox recombination

1997 • 807 citations

Treatment of Established Renal Cancer by Tumor Cells Engineered to Secrete Interleukin-4

1991 • 733 citations

Immunotherapy of Tumors with Autologous Tumor-Derived Heat Shock Protein Preparations

1997 • 699 citations

Interleukin 2 gene transfer into tumor cells abrogates tumorigenicity and induces protective immunity.

1990 • 628 citations

Southwest Oncology Group standard response criteria, endpoint definitions and toxicity criteria

1992 • 619 citations

Vaccination with irradiated autologous melanoma cells engineered to secrete human granulocyte–macrophage colony-stimulating factor generates potent antitumor immunity in patients with metastatic melanoma

1998 • 586 citations

Novel Allogeneic Granulocyte-Macrophage Colony-Stimulating Factor–Secreting Tumor Vaccine for Pancreatic Cancer: A Phase I Trial of Safety and Immune Activation

2001 • 576 citations

Improved survival in stage III melanoma patients with GM2 antibodies: a randomized trial of adjuvant vaccination with GM2 ganglioside.

1994 • 522 citations

Induction of immunity to prostate cancer antigens: results of a clinical trial of vaccination with irradiated autologous prostate tumor cells engineered to secrete granulocyte-macrophage colony-stimulating factor using ex vivo gene transfer.

1999 • 468 citations

Bioactivity of Autologous Irradiated Renal Cell Carcinoma Vaccines Generated by Ex Vivo Granulocyte-Macrophage Colony-Stimulating Factor Gene Transfer

1998 • 419 citations

Retroviral vector-mediated gamma-interferon gene transfer into tumor cells generates potent and long lasting antitumor immunity.

1990 • 414 citations

Vaccination With Irradiated, Autologous Melanoma Cells Engineered to Secrete Granulocyte-Macrophage Colony-Stimulating Factor by Adenoviral-Mediated Gene Transfer Augments Antitumor Immunity in Patients With Metastatic Melanoma

2003 • 306 citations

Vaccination With Irradiated Autologous Tumor Cells Engineered to Secrete Granulocyte-Macrophage Colony-Stimulating Factor Augments Antitumor Immunity in Some Patients With Metastatic Non–Small-Cell Lung Carcinoma

2003 • 296 citations

Expression of murine interleukin 7 in a murine glioma cell line results in reduced tumorigenicity in vivo.

1992 • 140 citations

Bronchioloalveolar carcinoma.

1996 • 123 citations

A phase III randomized, doúble-blind, multiinstitutional trial of vaccinia melanoma oncolysate-active specific immunotherapy for patients with stage II melanoma

1995 • 121 citations

A Universal Granulocyte-Macrophage Colony-Stimulating Factor-Producing Bystander Cell Line for Use in the Formulation of Autologous Tumor Cell-Based Vaccines

1999 • 116 citations

Perspective on allogeneic melanoma lysates in active specific immunotherapy.

1998 • 113 citations

A Phase III randomized study of interleukin-2 lymphokine-activated killer cell immunotherapy combined with chemotherapy or radiotherapy after curative or noncurative resection of primary lung carcinoma

1997 • 106 citations

IgM Anti-Ganglioside Antibodies Induced by Melanoma Cell Vaccine Correlate with Survival of Melanoma Patients

1999 • 79 citations

Genetic Immunotherapy of Established Tumors with Adenovirus-Murine Granulocyte-Macrophage Colony-Stimulating Factor

1997 • 79 citations

Polyvalent melanoma cell vaccine induces delayed-type hypersensitivity and in vitro cellular immune response.

1994 • 71 citations

Enhanced Immune Priming with Spatial Distribution of Paracrine Cytokine Vaccines

1996 • 67 citations

Adjuvant specific active lung cancer immunotherapy trials. Tumor-associated antigens

1987 • 47 citations

Phase II study of recombinant alpha interferon in the treatment of advanced non-small cell lung carcinoma.

1985 • 41 citations

Enhancement of complement-dependent cytotoxicity by polyvalent melanoma cell vaccine (CancerVax): Correlation with survival

1998 • 37 citations

Active specific immunotherapy with an autologous tumor cell vaccine in patients with resected non-small cell lung cancer.

1988 • 37 citations

Carcinoma of the lung: Immunotherapy with intradermal BCG and allogeneic tumor cells

1980 • 19 citations

Failure of specific active immunotherapy in lung cancer

1981 • 17 citations

Autologous x-irradiated tumour cells and percutaneous BCG in operable lung cancer.

1982 • 13 citations

Filamentous Particles in Human Alveolar Cell Carcinomas: Electron Miscroscopy Studies of Six Cases (Preliminary Report)

1972 • 13 citations

Virus-like intranuclear particles in bronchiolar-alveolar cell carcinoma.

1982 • 3 citations

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