Quantitative Cell-Based High-Content Screening for Vasopressin Receptor Agonists Using Transfluor®Technology

A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays

1999 • 6,580 citations

Evolving concepts in G protein-coupled receptor endocytosis: the role in receptor desensitization and signaling.

2001 • 1,794 citations

G Protein Pathways

2002 • 1,222 citations

The Many Faces of G Protein Signaling

1998 • 1,137 citations

G-protein-coupled receptors and signaling networks: emerging paradigms

2001 • 1,005 citations

Differential Affinities of Visual Arrestin, βArrestin1, and βArrestin2 for G Protein-coupled Receptors Delineate Two Major Classes of Receptors

2000 • 835 citations

The Pathways Connecting G Protein-coupled Receptors to the Nucleus through Divergent Mitogen-activated Protein Kinase Cascades

1998 • 819 citations

Association of β-Arrestin with G Protein-coupled Receptors during Clathrin-mediated Endocytosis Dictates the Profile of Receptor Resensitization

1999 • 549 citations

Physiological Regulation of G Protein-Linked Signaling

1999 • 449 citations

Classical and new roles of β-arrestins in the regulation of G-PROTEIN-COUPLED receptors

2001 • 446 citations

A β-Arrestin/Green Fluorescent Protein Biosensor for Detecting G Protein-coupled Receptor Activation

1997 • 420 citations

High content screening applied to large-scale cell biology

2003 • 286 citations

Cellular Trafficking of G Protein-coupled Receptor/β-Arrestin Endocytic Complexes

1999 • 213 citations

Characterization and Quantitation of NF-κB Nuclear Translocation Induced by Interleukin-1 and Tumor Necrosis Factor-α

1998 • 193 citations

Advances in High Content Screening for Drug Discovery

2003 • 184 citations

Identification of Drosophila Neuropeptide Receptors by G Protein-coupled Receptors-β-Arrestin2 Interactions

2003 • 129 citations

The Cellular Distribution of Fluorescently Labeled Arrestins Provides a Robust, Sensitive, and Universal Assay for Screening G Protein-Coupled Receptors

2002 • 117 citations

The use of constitutively active GPCRs in drug discovery and functional genomics

2002 • 108 citations

Signal transduction pathways of the human V1-vascular, V2-renal, V3-pituitary vasopressin and oxytocin receptors

1999 • 108 citations

Oxytocin as an antidiuretic hormone. II. Role of V2 vasopressin receptor

1995 • 95 citations

Quantification of G-Protein Coupled Receptor Internalization Using G-Protein Coupled Receptor-Green Fluorescent Protein Conjugates with the ArrayScan™ High-Content Screening System

1999 • 74 citations

Quantification of the Proliferation Index of Human Dermal Fibroblast Cultures with the ArrayScan™ High-Content Screening Reader

2004 • 73 citations

Cell-Based, High-Content Screen for Receptor Internalization, Recycling and Intracellular Trafficking

2000 • 64 citations

Pharmacological characterization of the human vasopressin receptor subtypes stably expressed in Chinese hamster ovary cells

1998 • 64 citations

Cell-Active Dual Specificity Phosphatase Inhibitors Identified by High-Content Screening

2003 • 62 citations

Relaxation of human isolated mesenteric arteries by vasopressin and desmopressin

1994 • 56 citations

Handbook of Assay Development in Drug Discovery

2006 • 53 citations

Identification of Gap Junction Blockers Using Automated Fluorescence Microscopy Imaging

2003 • 51 citations

Spatial Analysis of Key Signaling Proteins by High-content Solid-phase Cytometry in Hep3B Cells Treated with an Inhibitor of Cdc25 Dual-specificity Phosphatases

2001 • 44 citations

Vasopressin-stimulated Ca 2+ reabsorption in rabbit cortical collecting system: effects on cAMP and cytosolic Ca 2+

1996 • 43 citations

Quantitative analysis of agonist‐dependent parathyroid hormone receptor trafficking in whole cells using a functional green fluorescent protein conjugate

2001 • 37 citations

Synthesis and high content cell-based profiling of simplified analogues of the microtubule stabilizer (+)-discodermolide.

2002 • 33 citations

A Quantitative Cell-Based High-Content Screening Assay for the Epidermal Growth Factor Receptor-Specific Activation of Mitogen-Activated Protein Kinase

2004 • 31 citations

Vascular effects of [Arg8]vasopressin in the isolated perfused rat kidney

1996 • 23 citations

A Scalable High-Content Cytotoxicity Assay Insensitive to Changes in Mitochondrial Metabolic Activity

2003 • 23 citations

G Protein-Coupled Receptor Desensitization as a Measure of Signaling: Modeling of Arrestin Recruitment to Activated CCK-B Receptors

2003 • 19 citations

Characterization of vasopressin receptor in rat lung

1998 • 15 citations

The Use of Biosensors to Study GPCR Function: Applications for High-Content Screening

2002 • 14 citations

The Use of Biosensors to Study GPCR Function: Applications for High-Content Screening

2002 • 10 citations

TRANSFLUOR Provides a Universal Cell-Based Assay for Screening G-Protein-Coupled Receptors

2006 • 8 citations