An In Vivo Study of the Prefrontal Cortex of Schizophrenic Patients at Different Stages of Illness via Phosphorus Magnetic Resonance Spectroscopy

An Algorithm for Least-Squares Estimation of Nonlinear Parameters

1963 • 29,357 citations

Synaptic density in human frontal cortex — Developmental changes and effects of aging

1979 • 2,587 citations

Physiologic Dysfunction of Dorsolateral Prefrontal Cortex in Schizophrenia

1986 • 2,026 citations

Schizophrenia: Caused by a fault in programmed synaptic elimination during adolescence?

1982 • 1,352 citations

Regressive Events in Neurogenesis

1984 • 1,330 citations

Hypofrontality in Neuroleptic-Naive Patients and in Patients With Chronic Schizophrenia

1992 • 882 citations

Elimination of Synapses in the Developing Nervous System

1980 • 807 citations

Synaptogenesis in human visual cortex — evidence for synapse elimination during normal development

1982 • 747 citations

Physiological Dysfunction of Dorsolateral Prefrontal Cortex in Schizophrenia

1988 • 602 citations

Cerebral intracellular pH by ³¹ P nuclear magnetic resonance spectroscopy

1985 • 516 citations

Brain Morphology and Schizophrenia

1992 • 508 citations

Alterations in Brain High-Energy Phosphate and Membrane Phospholipid Metabolism in First-Episode, Drug-Naive Schizophrenics

1991 • 481 citations

Retrieval of frequencies, amplitudes, damping factors, and phases from time-domain signals using a linear least-squares procedure

1985 • 474 citations

Magnetic Resonance Imaging of the Brain in Schizophrenia

1990 • 440 citations

Widespread Cerebral Gray Matter Volume Deficits in Schizophrenia

1992 • 421 citations

Physiologic Dysfunction of Dorsolateral Prefrontal Cortex in Schizophrenia

1986 • 420 citations

Temporal lobe pathology in schizophrenia: a quantitative magnetic resonance imaging study

1989 • 416 citations

Frontostriatal Disorder of Cerebral Metabolism in Never-Medicated Schizophrenics

1992 • 330 citations

Glucose Metabolic Rate in Normals and Schizophrenics During the Continuous Performance Test Assessed by Positron Emission Tomography

1990 • 321 citations

The Frontal Lobes, Basal Ganglia, and Temporal Lobes as Sites for Schizophrenia

1990 • 312 citations

Human in vivo NMR spectroscopy in diagnostic medicine: clinical tool or research probe?

1989 • 275 citations

Structural abnormalities in deficit and nondeficit schizophrenia

1993 • 260 citations

Overproduction and Elimination of Retinal Axons in the Fetal Rhesus Monkey

1983 • 246 citations

Quantitative Neuroanatomy in Schizophrenia

1988 • 241 citations

Mechanisms of Magnesium Transport

1991 • 229 citations

Increased plasma phospholipase-A2 activity in schizophrenic patients: Reduction after neuroleptic therapy

1987 • 216 citations

Phenomenological correlates of metabolic activity in 18 patients with chronic schizophrenia

1987 • 216 citations

NMR Studies of Intracellular Metal Ions in Intact Cells and Tissues

1984 • 214 citations

Physiological Dysfunction of Dorsolateral Prefrontal Cortex in Schizophrenia

1988 • 207 citations

Increased serum phospholipase A2 activity in schizophrenia: a replication study.

1990 • 191 citations

Voltage-dependent block by intracellular Mg2+ of N-methyl-D-aspartate-activated channels

1990 • 186 citations

31P Nuclear Magnetic Resonance Studies of Phosphoglyceride Metabolism in Developing and Degenerating Brain

1987 • 158 citations

Dysfunction in a prefrontal substrate of sustained attention in schizophrenia

1987 • 145 citations

Is the Mechanism of Prefrontal Hypofunction in Depression the Same as in Schizophrenia?

1993 • 121 citations

31P Nuclear Magnetic Resonance Spectroscopy: Neurodevelopment and Schizophrenia

1993 • 114 citations

Membrane phospholipid metabolism and schizophrenia: an in vivo 31P-MR spectroscopy study

1994 • 99 citations

Erythrocyte membrane phospholipids in psychotic patients

1993 • 97 citations

Frontal, temporal, and striatal proton relaxation times in schizophrenic patients and normal comparison subjects

1992 • 71 citations

Phosphorus-31 MR spectroscopic imaging (MRSI) of normal and pathological human brains

1992 • 67 citations

Magnetic resonance spectroscopy in psychiatry: potential, pitfalls, and promise [published erratum appears in Am J Psychiatry 1992 Mar;149(3):431]

1991 • 67 citations

Increased platelet membrane lysophosphatidylcholine in schizophrenia

1991 • 58 citations

EEG coherence of prefrontal areas in normal and schizophrenic males during perceptual activation

1991 • 58 citations

The Distribution of the Phospholipid Fractions in the Red Cell Membrane of Schizophrenics

1972 • 54 citations

Membrane abnormalities in the psychoses and affective disorders

1984 • 51 citations

Localized 31P NMR spectroscopy of the amt human brain in vivo using stimulated-echo (STEAM) sequences

1990 • 49 citations

Coherence on Electroencephalography and Aberrant Functional Organisation of the Brain in Schizophrenic Patients During Activation Tasks

1991 • 38 citations

Platelet and erythrocyte membrane lipid and phospholipid patterns in different types of mental patients

1981 • 36 citations

Kinetic evidence for decreased methionine adenosyltransferase activity in erythrocytes from schizophrenics

1982 • 30 citations

Red cell phospholipids in schizophrenia

1982 • 30 citations

Localization in in Vivo 31P NMR spectroscopy by combining surface coils and slice-selective saturation

1987 • 30 citations

Influence of Mg2+ and pH on n.m.r. spectra and radioligand binding of inositol 1,4,5-trisphosphate

1991 • 28 citations

Characteristics of phospholipid methylation in human erythrocyte ghosts: Relationship(s) to the psychoses and affective disorders

1985 • 24 citations

BLOOD-LEVELS OF S-ADENOSYLMETHIONINE IN SCHIZOPHRENIA

1975 • 22 citations

Phospholipase A2 activity in Epstein-Barr virus-transformed lymphoblast cells from schizophrenic patients

1991 • 19 citations

More on Chlamydia Pneumonia and Meningoencephalitis

1995 • 14 citations