PDZ domains determine the native oligomeric structure of the DegP (HtrA) protease

The Release of Enzymes from Escherichia coli by Osmotic Shock and during the Formation of Spheroplasts

1965 • 1,490 citations

The Proteasome: Paradigm of a Self-Compartmentalizing Protease

1998 • 1,483 citations

Functional inactivation of genes by dominant negative mutations

1987 • 1,174 citations

Crystal Structures of a Complexed and Peptide-Free Membrane Protein–Binding Domain: Molecular Basis of Peptide Recognition by PDZ

1996 • 1,127 citations

Protein volumes and hydration effects. The calculations of partial specific volumes, neutron scattering matchpoints and 280-nm absorption coefficients for proteins and glycoproteins from amino acid sequences

1986 • 575 citations

Protein quality control: triage by chaperones and proteases.

1997 • 543 citations

PDZ Domains: Targeting signalling molecules to sub‐membranous sites

1997 • 411 citations

The HtrA family of serine proteases

1997 • 388 citations

An Escherichia coli mutation preventing degradation of abnormal periplasmic proteins.

1988 • 374 citations

The permeability of the wall fabric of Escherichia coli and Bacillus subtilis

1996 • 364 citations

Identification, characterization, and mapping of the Escherichia coli htrA gene, whose product is essential for bacterial growth only at elevated temperatures

1989 • 342 citations

The Cpx two-component signal transduction pathway of Escherichia coli regulates transcription of the gene specifying the stress-inducible periplasmic protease, DegP.

1995 • 325 citations

The HtrA (DegP) protein, essential for Escherichia coli survival at high temperatures, is an endopeptidase

1990 • 317 citations

rpoE, the gene encoding the second heat-shock sigma factor, sigma E, in Escherichia coli.

1995 • 312 citations

The rpoE gene encoding the sigma E (sigma 24) heat shock sigma factor of Escherichia coli.

1995 • 295 citations

Evidence for PDZ domains in bacteria, yeast, and plants

1997 • 237 citations

Crystal structure of the hCASK PDZ domain reveals the structural basis of class II PDZ domain target recognition

1998 • 179 citations

Protein Translocation Channels in the Proteasome and Other Proteases

1997 • 167 citations

The DegP and DegQ periplasmic endoproteases of Escherichia coli: specificity for cleavage sites and substrate conformation

1996 • 139 citations

[50] Proteases in Escherichia coli

1981 • 125 citations

Elasticity of the sacculus of Escherichia coli

1992 • 119 citations

PDZ-like Domains Mediate Binding Specificity in the Clp/Hsp100 Family of Chaperones and Protease Regulatory Subunits

1997 • 108 citations

Tricorn Protease—The Core of a Modular Proteolytic System

1996 • 106 citations

Subcellular distribution of various proteases in Escherichia coli.

1982 • 105 citations

Folding of a Mutant Maltose-binding Protein of Escherichia coli Which Forms Inclusion Bodies

1996 • 85 citations

Degradation versus Aggregation of Misfolded Maltose-binding Protein in the Periplasm of Escherichia coli

1998 • 56 citations

Probing the Structural Role of an αβ Loop of Maltose-binding Protein by Mutagenesis: Heat-shock Induction by Loop Variants of the Maltose-binding Protein that Form Periplasmic Inclusion Bodies

1996 • 42 citations

Defective export in Escherichia coli caused by DsbA'-PhoA hybrid proteins whose DsbA' domain cannot fold into a conformation resistant to periplasmic proteases

1997 • 15 citations