Testosterone-mediated modulation of HERG blockade by proarrhythmic agents11Abbreviations: TdP, torsades de pointes; HERG, human ether-a-go-go related gene; DMSO, dimethyl sulfoxide.

A mechanistic link between an inherited and an acquird cardiac arrthytmia: HERG encodes the IKr potassium channel

1995 • 2,391 citations

Coassembly of KVLQT1 and minK (IsK) proteins to form cardiac IKS potassium channel

1996 • 1,741 citations

Antipsychotic drug doses and neuroleptic/dopamine receptors

1976 • 1,623 citations

KvLQT1 and IsK (minK) proteins associate to form the IKS cardiac potassium current

1996 • 1,585 citations

MiRP1 Forms IKr Potassium Channels with HERG and Is Associated with Cardiac Arrhythmia

1999 • 1,344 citations

HERG, a Human Inward Rectifier in the Voltage-Gated Potassium Channel Family

1995 • 1,216 citations

Female gender as a risk factor for torsades de pointes associated with cardiovascular drugs

1993 • 843 citations

The inward rectification mechanism of the HERG cardiac potassium channel

1996 • 754 citations

Non-genomic and genomic effects of steroids on neural activity

1991 • 731 citations

Female Gender as a Risk Factor for Torsades de Pointes Associated With Cardiovascular Drugs

1993 • 702 citations

Sex differences in the evolution of the electrocardiographic QT interval with age.

1992 • 634 citations

Mechanism of the Cardiotoxic Actions of Terfenadine

1993 • 627 citations

A minK–HERG complex regulates the cardiac potassium current IKr

1997 • 376 citations

Sex Hormones Prolong the QT Interval and Downregulate Potassium Channel Expression in the Rabbit Heart

1996 • 368 citations

[15] Maintenance of Xenopus laevis and oocyte injection

1992 • 267 citations

The inhibitory effect of the antipsychotic drug haloperidol on HERG potassium channels expressed in Xenopus oocytes

1997 • 225 citations

Gender difference in the cycle length-dependent QT and potassium currents in rabbits.

1998 • 208 citations

The induction of oocyte maturation: transmembrane signaling events and regulation of the cell cycle

1989 • 189 citations

Cloning and expression of the delayed-rectifier IsK channel from neonatal rat heart and diethylstilbestrol-primed rat uterus.

1990 • 189 citations

The antipsychotic agent sertindole is a high affinity antagonist of the human cardiac potassium channel HERG.

1998 • 170 citations

The Association Between Intravenous Haloperidol and Torsades de Pointes

1995 • 118 citations

Proarrhythmic effects of antiarrhythmic drugs

1987 • 110 citations

Steroid production by Xenopus ovarian follicles at different developmental stages

1983 • 90 citations

Psychotropic drug block voltage-gated ion channels in neuroblastoma cells

1989 • 89 citations

Nongenomic Steroid Action: Independent Targeting of a Plasma Membrane Calcium Channel and a Tyrosine Kinase

1995 • 82 citations

Effects of estradiol and progesterone on voltage-gated calcium and potassium conductances in rat CA1 hippocampal neurons

1995 • 81 citations

Mitosis-promoting factor-mediated suppression of a cloned delayed rectifier potassium channel expressed in Xenopus oocytes

1997 • 77 citations

Effects of estrogen on action potential and membrane currents in guinea pig ventricular myocytes

1999 • 75 citations

Modulation by cAMP of a slowly activating potassium channel expressed in Xenopus oocytes

1992 • 72 citations

Electrical membrane properties of the Xenopus laevis oocyte during progesterone-induced meiotic maturation

1981 • 71 citations

Life-Threatening Ventricular Arrhythmia (Torsades de Pointes) after Haloperidol Overdose

1991 • 67 citations

Human Ether-a-gogo Related Gene (HERG) K Channels as Pharmacological Targets

1998 • 65 citations

Blockade of HERG channels by the class III antiarrhythmic azimilide: mode of action

1998 • 62 citations

Inhibition of P-type and N-type calcium channels by dopamine receptor antagonists.

1994 • 60 citations

Preferential block of T-type calcium channels by neuroleptics in neural crest-derived rat and human C cell lines.

1992 • 54 citations

Suppression of mammalian K+ channel family by ebastine.

1997 • 50 citations

Blockade of low and high threshold Ca2+ channels by diphenylbutylpiperidine antipsychotics linked to inhibition of prolactin gene expression.

1990 • 49 citations

Comparative Effects of Loratadine and Terfenadine on Cardiac K+ Channels

1997 • 44 citations

Differential expression of Isk mRNAs in mouse tissue during development and pregnancy

1994 • 40 citations

Inhibition of minK protein induced K+ channels in Xenopus oocytes by estrogens

1996 • 36 citations

Production of androgen and estradiol-17β by Xenopus ovaries treated with gonadotropins in vitro

1981 • 23 citations

Testosterone-induced meiotic maturation of Xenopus laevis oocytes: Evidence for an early effect in the synergistic action of insulin

1985 • 20 citations

Molecular mechanisms of arrhythmias.

1998 • 18 citations

MECHANISM OF CARDIOTOXIC ACTIONS OF TERFENADINE

1994 • 6 citations