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HERG, a Human Inward Rectifier in the Voltage-Gated Potassium Channel Family

Data up to Jan 2025

Published1995
Citations1,216
References34

Total Citations Per Year

Abstract

References (34)

A mechanistic link between an inherited and an acquird cardiac arrthytmia: HERG encodes the IKr potassium channel

1995 • 2,391 citations

A molecular basis for cardiac arrhythmia: HERG mutations cause long QT syndrome

1995 • 2,263 citations

Biophysical and Molecular Mechanisms of Shaker Potassium Channel Inactivation

1990 • 1,528 citations

Two components of cardiac delayed rectifier K+ current. Differential sensitivity to block by class III antiarrhythmic agents.

1990 • 1,467 citations

Structural parts involved in activation and inactivation of the sodium channel

1989 • 1,189 citations

Subunit stoichiometry of a mammalian K+ channel determined by construction of multimeric cDNAs

1992 • 1,067 citations

Primary structure and functional expression of a mouse inward rectifier potassium channel

1993 • 1,004 citations

A family of potassium channel genes related to eag in Drosophila and mammals.

1994 • 960 citations

Cloning and expression of an inwardly rectifying ATP-regulated potassium channel

1993 • 935 citations

Potassium channel block by cytoplasmic polyamines as the mechanism of intrinsic rectification

1994 • 847 citations

A model of cardiac electrical activity incorporating ionic pumps and concentration changes

1985 • 835 citations

Cloning of Genomic and Complementary DNA from Shaker , a Putative Potassium Channel Gene from Drosophila

1987 • 721 citations

Two types of inactivation in Shaker K+ channels: Effects of alterations in the carboxy-terminal region

1991 • 688 citations

A general method for rapid site-directed mutagenesis using the polymerase chain reaction

1990 • 642 citations

A Component of Calcium-activated Potassium Channels Encoded by the Drosophila slo Locus

1991 • 629 citations

Ohmic conductance through the inwardly rectifying K channel and blocking by internal Mg2+

1987 • 597 citations

Spermine and Spermidine as Gating Molecules for Inward Rectifier K + Channels

1994 • 520 citations

Alteration of voltage-dependence of Shaker potassium channel by mutations in the S4 sequence

1991 • 507 citations

Inward rectification of a potassium channel in cardiac ventricular cells depends on internal magnesium ions.

1987 • 495 citations

Potassium current and the effect of cesium on this current during anomalous rectification of the egg cell membrane of a starfish.

1976 • 472 citations

Expression of an inward-rectifying potassium channel by the Arabidopsis KAT1 cDNA

1992 • 449 citations

Anomalous Rectification in the Squid Giant Axon Injected with Tetraethylammonium Chloride

1965 • 439 citations

Inactivation of the Potassium Conductance and Related Phenomena Caused by Quaternary Ammonium Ion Injection in Squid Axons

1969 • 427 citations

A Distinct Potassium Channel Polypeptide Encoded by the Drosophila eag Locus

1991 • 361 citations

THE BEHAVIOR OF FOUR NEUROLOGICAL MUTANTS OF DROSOPHILA

1969 • 306 citations

Voltage-sensing residues in the S4 region of a mammalian K+ channel

1991 • 275 citations

Blocking effects of barium and hydrogen ions on the potassium current during anomalous rectification in the starfish egg.

1978 • 271 citations

Ether-à-go-go encodes a voltage-gated channel permeable to K+ and Ca2+ and modulated by cAMP

1993 • 240 citations

Neurogenetic Analysis of Potassium Currents in Drosophila: Synergistic Effects on Neuromuscular Transmission in Double Mutants

1983 • 185 citations

Functional expression of a rat homologue of the voltage gated either á go-go potassium channel reveals differences in selectivity and activation kinetics between the Drosophila channel and its mammalian counterpart.

1994 • 183 citations

Primary structure and characterization of a small-conductance inwardly rectifying potassium channel from human hippocampus.

1994 • 139 citations

Cloning and expression of a novel human brain inward rectifier potassium channel.

1994 • 108 citations

[14]Xenopus oocyte microinjection: From gene to protein

1992 • 102 citations

Comparative Assessment of Ibutilide, D-Sotalol, Clofilium, E-4031, and UK-68, 798 in a Rabbit Model of Proarrhythmia

1993 • 96 citations

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HERG, a Human Inward Rectifier in the Voltage-Gated Potassium Channel Family (1995) – Science | Metascience Observatory Explorer