Effect of endocrine therapy on growth of T61 human breast cancer xenografts is directly correlated to a specific down-regulation of insulin-like growth factor II (IGF-II)

Insulin-like growth factor I receptor primary structure: comparison with insulin receptor suggests structural determinants that define functional specificity.

1986 • 1,866 citations

Evidence that transforming growth factor-β is a hormonally regulated negative growth factor in human breast cancer cells

1987 • 998 citations

Cloning of cDNA sequences of hormone-regulated genes from the MCF-7 human breast cancer cell line

1982 • 727 citations

Estrogenic Regulation of Growth and Polypeptide Growth Factor Secretion in Human Breast Carcinoma

1987 • 576 citations

Expression of Transforming Growth Factor α and its Messenger Ribonucleic Acid in Human Breast Cancer: Its Regulation by Estrogen and its Possible Functional Significance

1988 • 440 citations

Monoclonal antibodies to receptors for insulin and somatomedin-C.

1983 • 423 citations

Analysis of Insulin-Like Growth Factor I Gene Expression in Malignancy: Evidence for a Paracrine Role in Human Breast Cancer

1989 • 403 citations

Randomized Clinical Trial of Diethylstilbestrol versus Tamoxifen in Postmenopausal Women with Advanced Breast Cancer

1981 • 334 citations

Blockade of the type I somatomedin receptor inhibits growth of human breast cancer cells in athymic mice.

1989 • 334 citations

Sequence of a cDNA clone encoding human preproinsulin-like growth factor II

1984 • 326 citations

Insulin-like growth factor receptor expression and function in human breast cancer.

1990 • 321 citations

Estrogen-Induced Factors of Breast Cancer Cells Partially Replace Estrogen to Promote Tumor Growth

1986 • 273 citations

Insulin-Like Growth Factor-ll (IGF-II): A Potential Autocrine/Paracrine Growth Factor for Human Breast Cancer Acting via the IGF-I Receptor

1989 • 248 citations

Transforming growth factor beta: potential autocrine growth inhibitor of estrogen receptor-negative human breast cancer cells.

1988 • 247 citations

Insulin-like growth factor II mRNA expression in human breast cancer.

1988 • 245 citations

The human cation-independent mannose 6-phosphate receptor. Cloning and sequence of the full-length cDNA and expression of functional receptor in COS cells.

1988 • 244 citations

Insulin-like growth factor 1 receptors in human breast cancer and their relation to estradiol and progesterone receptors.

1988 • 173 citations

Multihormonal Regulation of Insulin-Like Growth Factor-I-Related Protein in MCF-7 Human Breast Cancer Cells

1988 • 161 citations

An antibody to the receptor for insulin-like growth factor I inhibits the growth of MCF-7 cells in tissue culture

1987 • 155 citations

Receptor binding and growth-promoting activity of insulin-like growth factors in human breast cancer cells (T-47D) in culture.

1984 • 139 citations

Interactions of Cathepsin-D and Insulin-Like Growth Factor-II (IGF-II) on the IGF-II/Mannose-6-Phosphate Receptor in Human Breast CancerCells and Possible Consequences on Mitogenic Activity of IGF-II

1990 • 119 citations

Effect of tamoxifen on plasma insulin-like growth factor I in patients with breast cancer.

1989 • 118 citations

Demonstration of insulin-like growth factor (IGF-I and -II) receptors and binding protein in human breast cancer cell lines

1988 • 110 citations

Effect on growth and cell cycle kinetics of estradiol and tamoxifen on MCF-7 human breast cancer cells grown in vitro and in nude mice.

1989 • 91 citations

Production of Mammastatin, a Tissue-Specific Growth Inhibitor, by Normal Human Mammary Cells

1989 • 88 citations

Antibody to type I insulinlike growth factor receptor inhibits growth of Wilms' tumor in culture and in athymic mice.

1989 • 88 citations

Tamoxifen versus ethinyl estradiol in the treatment of postmenopausal women with advanced breast cancer.

1981 • 63 citations

A Novel Human Insulin-Like Growth Factor I Messenger RNA is Expressed in Normal and Tumor Cells

1990 • 59 citations

Amino-terminal propeptide of type III procollagen: a new prognosis indicator in human ovarian cancer.

1989 • 39 citations

Serum steroid levels in intact and endocrine ablated BALB/C nude mice and their intact littermates

1986 • 30 citations

Effect of tamoxifen on the receptor-positive T61 and the receptor-negative T60 human breast carcinomas grown in nude mice

1985 • 29 citations

Characterization of the T61 human breast carcinoma established in nude mice

1985 • 24 citations

Dose-Dependent Effect of 17β-Estradiol Determined by Growth Curves and Flow Cytometric DNA Analysis of a Human Breast Carcinoma (T61) Grown in Nude Mice

1985 • 20 citations

Endocrine therapy of human breast cancer cells: the role of secreted polypeptide growth factors.

1989 • 18 citations

Immune-deficient animals in experimental medicine

1990 • 17 citations

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