Regulation of the Heat-Shock Response

Heat Shock Transcription Factors: Structure and Regulation

1995 • 1,179 citations

Stress proteins in biology and medicine

1990 • 731 citations

ATP-dependent nucleosome disruption at a heat-shock promoter mediated by binding of GAGA transcription factor

1994 • 662 citations

Molecular chaperones and protein folding in plants

1996 • 606 citations

Stress proteins in biology and medicine

1990 • 502 citations

Regulation of Heat Shock Factor Trimer Formation: Role of a Conserved Leucine Zipper

1993 • 486 citations

The consequences of expressing hsp70 in Drosophila cells at normal temperatures.

1992 • 398 citations

Sequential Phosphorylation by Mitogen-activated Protein Kinase and Glycogen Synthase Kinase 3 Represses Transcriptional Activation by Heat Shock Factor-1

1996 • 381 citations

Stress-induced transcriptional activation

1995 • 325 citations

Three tomato genes code for heat stress transcription factors with a region of remarkable homology to the DNA-binding domain of the yeast HSF.

1990 • 321 citations

Repression of the Heat Shock Factor 1 Transcriptional Activation Domain Is Modulated by Constitutive Phosphorylation

1997 • 316 citations

Multiple functions ofDrosophilaheat shock transcription factorin vivo

1997 • 300 citations

Synthesis of Small Heat-Shock Proteins Is Part of the Developmental Program of Late Seed Maturation

1996 • 271 citations

Characterization of a novel chicken heat shock transcription factor, heat shock factor 3, suggests a new regulatory pathway.

1993 • 264 citations

Derepression of the activity of genetically engineered heat shock factor causes constitutive synthesis of heat shock proteins and increased thermotolerance in transgenic Arabidopsis

1995 • 246 citations

Repression of human heat shock factor 1 activity at control temperature by phosphorylation.

1996 • 231 citations

Hsp26 is not required for growth at high temperatures, nor for thermotolerance, spore development, or germination

1986 • 231 citations

The Hsf world: classification and properties of plant heat stress transcription factors

1996 • 201 citations

Membrane lipid perturbation modifies the set point of the temperature of heat shock response in yeast.

1996 • 200 citations

Activation of the DNA-Binding Ability of Human Heat Shock Transcription Factor 1 May Involve the Transition from an Intramolecular to an Intermolecular Triple-Stranded Coiled-Coil Structure

1994 • 198 citations

HSF3, a new heat shock factor from Arabidopsis thaliana, derepresses the heat shock response and confers thermotolerance when overexpressed in transgenic plants

1998 • 190 citations

An Hsp70 antisense gene affects the expression of HSP70/HSC70, the regulation of HSF, and the acquisition of thermotolerance in transgenic Arabidopsis thaliana

1996 • 184 citations

A new method for manipulating transgenes: engineering heat tolerance in a complex, multicellular organism

1993 • 167 citations

Promoter melting and TFIID complexes on Drosophila genes in vivo.

1992 • 155 citations

Alfalfa heat shock genes are differentially expressed during somatic embryogenesis

1991 • 152 citations

Expression of sunflower low-molecular-weight heat-shock proteins during embryogenesis and persistence after germination: localization and possible functional implications

1994 • 145 citations

Evidence for a role of Hsp 70 in the regulation of the heat shock response in mammalian cells

1996 • 141 citations

The Regulatory Domain of Human Heat Shock Factor 1 Is Sufficient To Sense Heat Stress

1996 • 137 citations

Synergistic effect of upstream sequences, CCAAT box elements, and HSE sequences for enhanced expression of chimaeric heat shock genes in transgenic tobacco

1992 • 137 citations

Arabidopsis heat shock factor: isolation and characterization of the gene and the recombinant protein

1994 • 135 citations

Transcriptional regulation of SSA3, an HSP70 gene from Saccharomyces cerevisiae.

1990 • 125 citations

Genetic evidence for a functional relationship between Hsp104 and Hsp70

1993 • 124 citations

A short element required for turning off heat shock transcription factor: evidence that phosphorylation enhances deactivation.

1994 • 123 citations

A Conserved Domain of the viviparous-1 Gene Product Enhances the DNA Binding Activity of the bZIP Protein EmBP-1 and Other Transcription Factors

1996 • 122 citations

Promoter specificity and deletion analysis of three heat stress transcription factors of tomato

1993 • 115 citations

Stable transformation of an Arabidopsis cell suspension culture with firefly luciferase providing a cellular system for analysis of chaperone activity in vivo.

1997 • 115 citations

The expression of a small heat shock gene is activated during induction of tobacco pollen embryogenesis by starvation*

1995 • 113 citations

Intracellular distribution and identification of the nuclear localization signals of two plant heat-stress transcription factors

1997 • 111 citations

Activation of the DNA-binding ability of human heat shock transcription factor 1 may involve the transition from an intramolecular to an intermolecular triple-stranded coiled-coil structure.

1994 • 105 citations

Hydrophobic coiled-coil domains regulate the subcellular localization of human heat shock factor 2.

1993 • 90 citations

An SAR sequence containing 395 bp DNA fragment mediates enhanced, gene-dosage-correlated expression of a chimaeric heat shock gene in transgenic tobacco plants

1993 • 86 citations

Regulation of Drosophila Heat Shock Factor Trimerization: Global Sequence Requirements and Independence of Nuclear Localization

1996 • 86 citations

Identification of the C-terminal activator domain in yeast heat shock factor: independent control of transient and sustained transcriptional activity.

1993 • 85 citations

Expression of heat shock factor and heat shock protein 70 genes during maize pollen development

1995 • 76 citations

Temperature-dependent regulation of a heterologous transcriptional activation domain fused to yeast heat shock transcription factor.

1992 • 75 citations

Disruption of the gene for hsp30, an alpha-crystallin-related heat shock protein of Neurospora crassa, causes defects in thermotolerance.

1995 • 74 citations

The function of plant heat shock promoter elements in the regulated expression of chimaeric genes in transgenic tobacco

1989 • 73 citations

The C-terminal region of Drosophila heat shock factor (HSF) contains a constitutively functional transactivation domain

1996 • 70 citations

Regulatory domains of the Gmhsp17.5-E heat shock promoter of soybean.

1989 • 67 citations

Construction of a heat-inducible gene for plants. Demonstration of heat-inducible activity of the Drosophila hsp70 promoter in plants

1985 • 66 citations

Phosphorylation by a Cyclin-Dependent Kinase Modulates DNA Binding of the Arabidopsis Heat-Shock Transcription Factor HSF1 in Vitro

1997 • 62 citations

Nuclear entry, oligomerization, and DNA binding of the Drosophila heat shock transcription factor are regulated by a unique nuclear localization sequence.

1997 • 57 citations

The independent stage‐specific expression of the 18‐kDa heat shock protein genes during microsporogenesis in Zea mays L

1993 • 55 citations

Mutational analysis of a plant heat shock element

1992 • 51 citations

Isolation and characterization of six heat shock transcription factor cDNA clones from soybean

1995 • 45 citations

Arabidopsis heat shock factor is constitutively active inDrosophila and human cells

1995 • 45 citations

New Insights into ABA-Mediated Processes

1997 • 39 citations

Complexity and Genetic Variability of Heat-Shock Protein Expression in Isolated Maize Microspores

1996 • 31 citations

Heat shock elements are involved in heat shock promoter activation during tobacco seed maturation

1996 • 29 citations

Plant heat shock transcription factors: positive and negative aspects of regulation

1997 • 23 citations

Constitutive transcription of a soybean heat‐shock gene by a cauliflower mosaic virus promoter in transgenic tobacco plants

1987 • 15 citations