Lymph node fibroblastic reticular cells directly present peripheral tissue antigen under steady-state and inflammatory conditions

Projection of an Immunological Self Shadow Within the Thymus by the Aire Protein

2002 • 2,371 citations

Promiscuous gene expression in medullary thymic epithelial cells mirrors the peripheral self

2001 • 1,043 citations

Double-Stranded RNA Is Produced by Positive-Strand RNA Viruses and DNA Viruses but Not in Detectable Amounts by Negative-Strand RNA Viruses

2006 • 932 citations

Stromal Cell Networks Regulate Lymphocyte Entry, Migration, and Territoriality in Lymph Nodes

2006 • 907 citations

Fibroblastic reticular cells in lymph nodes regulate the homeostasis of naive T cells

2007 • 854 citations

Lipopolysaccharide Activates Distinct Signaling Pathways in Intestinal Epithelial Cell Lines Expressing Toll-Like Receptors

2000 • 754 citations

Toll-Like Receptors 3 and 4 Are Expressed by Human Bone Marrow-Derived Mesenchymal Stem Cells and Can Inhibit Their T-Cell Modulatory Activity by Impairing Notch Signaling

2007 • 478 citations

Deletional Tolerance Mediated by Extrathymic Aire-Expressing Cells

2008 • 468 citations

Lymph Node Fibroblastic Reticular Cells Construct the Stromal Reticulum via Contact with Lymphocytes

2004 • 351 citations

Peripheral antigen display by lymph node stroma promotes T cell tolerance to intestinal self

2006 • 346 citations

Toll-like receptor-mediated control of HBV replication by nonparenchymal liver cells in mice

2007 • 264 citations

Mesenchymal progenitor self-renewal deficiency leads to age-dependent osteoporosis in Sca-1/Ly-6A null mice

2003 • 237 citations

Viral targeting of fibroblastic reticular cells contributes to immunosuppression and persistence during chronic infection

2007 • 223 citations

Sophisticated strategies for information encounter in the lymph node: the reticular network as a conduit of soluble information and a highway for cell traffic.

1996 • 192 citations

Intracellularly Expressed TLR2s and TLR4s Contribution to an Immunosilent Environment at the Ocular Mucosal Epithelium

2004 • 157 citations

Expression of Intestine-Specific Antigen Reveals Novel Pathways of CD8 T Cell Tolerance Induction

2000 • 138 citations

Deletional Self-Tolerance to a Melanocyte/Melanoma Antigen Derived from Tyrosinase Is Mediated by a Radio-Resistant Cell in Peripheral and Mesenteric Lymph Nodes

2007 • 136 citations

Deaf1 isoforms control the expression of genes encoding peripheral tissue antigens in the pancreatic lymph nodes during type 1 diabetes

2009 • 132 citations

Intestinal Tolerance Is Converted to Autoimmune Enteritis upon PD-1 Ligand Blockade

2009 • 119 citations

A Specific Anti-Aire Antibody Reveals Aire Expression Is Restricted to Medullary Thymic Epithelial Cells and Not Expressed in Periphery

2008 • 105 citations

The phenotypic heterogeneity of mouse thymic stromal cells.

1990 • 104 citations

Direct Presentation of Antigen by Lymph Node Stromal Cells Protects Against CD8 T-Cell-Mediated Intestinal Autoimmunity

2008 • 85 citations

Ablation and Regeneration of Tolerance-Inducing Medullary Thymic Epithelial Cells after Cyclosporine, Cyclophosphamide, and Dexamethasone Treatment

2009 • 84 citations

Cutting Edge: Inflammatory Signals Drive Organ-Specific Autoimmunity to Normally Cross-Tolerizing Endogenous Antigen

2002 • 75 citations

Cutting Edge: TLR Ligands Are Not Sufficient to Break Cross-Tolerance to Self-Antigens

2005 • 61 citations

Sca-1 expression is required for efficient remodeling of the extracellular matrix during skeletal muscle regeneration

2008 • 61 citations

Concordant loss of melanoma differentiation antigens in synchronous and asynchronous melanoma metastases: implications for immunotherapy

2006 • 28 citations

Lessons from Thymic Epithelial Heterogeneity: FoxN1 and Tissue-Restricted Gene Expression by Extrathymic, Endodermally Derived Epithelium

2009 • 10 citations