The Saccharomyces cerevisiae MLH 3 gene functions in MSH3-dependent suppression of frameshift mutations

A ten-minute DNA preparation from yeast efficiently releases autonomous plasmids for transformaion of Escherichia coli

1987 • 2,493 citations

Multifunctional yeast high-copy-number shuttle vectors

1992 • 1,656 citations

Mutations of two P/WS homologues in hereditary nonpolyposis colon cancer

1994 • 1,544 citations

Cdi1, a human G1 and S phase protein phosphatase that associates with Cdk2

1993 • 1,531 citations

MISMATCH REPAIR IN REPLICATION FIDELITY, GENETIC RECOMBINATION, AND CANCER BIOLOGY

1996 • 1,485 citations

The distribution of the numbers of mutants in bacterial populations

1949 • 1,471 citations

Methylation of the hMLH1 promoter correlates with lack of expression of hMLH1 in sporadic colon tumors and mismatch repair-defective human tumor cell lines.

1997 • 1,465 citations

[19] Targeting, disruption, replacement, and allele rescue: Integrative DNA transformation in yeast

1991 • 1,369 citations

Mutations predisposing to hereditary nonpolyposis colorectal cancer: Database and results of a collaborative study. The International Collaborative Group on Hereditary Nonpolyposis Colorectal Cancer

1997 • 756 citations

Diagnostic microsatellite instability: definition and correlation with mismatch repair protein expression.

1997 • 751 citations

The barrier to recombination between Escherichia coli and Salmonella typhimurium is disrupted in mismatch-repair mutants

1989 • 728 citations

Isolation of an hMSH2-p160 Heterodimer That Restores DNA Mismatch Repair to Tumor Cells

1995 • 599 citations

Biochemistry and genetics of eukaryotic mismatch repair.

1996 • 598 citations

Redundancy of Saccharomyces cerevisiae MSH3 and MSH6 in MSH2-dependent mismatch repair.

1996 • 576 citations

hMSH2 forms specific mispair-binding complexes with hMSH3 and hMSH6

1996 • 541 citations

Correlation of Two-Hybrid Affinity Data with In Vitro Measurements

1995 • 536 citations

GTBP, a 160-Kilodalton Protein Essential for Mismatch-binding Activity in Human Cells

1995 • 528 citations

Microsatellite instability in colorectal cancer: different mutator phenotypes and the principal involvement of hMLH1.

1998 • 523 citations

A Novel Mutation Avoidance Mechanism Dependent on S. cerevisiae RAD27 Is Distinct from DNA Mismatch Repair

1997 • 434 citations

Restoration of mismatch repair to nuclear extracts of H6 colorectal tumor cells by a heterodimer of human MutL homologs.

1995 • 403 citations

Microsatellite Instability in Yeast: Dependence on Repeat Unit Size and DNA Mismatch Repair Genes

1997 • 381 citations

Tumour susceptibility and spontaneous mutation in mice deficient in Mlh1, Pms1 and Pms2 DMA mismatch repair

1998 • 351 citations

Interaction mating reveals binary and ternary connections between Drosophila cell cycle regulators.

1994 • 306 citations

MLH1, PMS1, and MSH2 Interactions During the Initiation of DNA Mismatch Repair in Yeast

1994 • 287 citations

Interaction between mismatch repair and genetic recombination in Saccharomyces cerevisiae.

1994 • 236 citations

Dual roles for DNA sequence identity and the mismatch repair system in the regulation of mitotic crossing-over in yeast

1997 • 230 citations

Dual requirement in yeast DNA mismatch repair for MLH1 and PMS1, two homologs of the bacterial mutL gene.

1994 • 222 citations

Mismatch correction at O6-methylguanine residues in E. coli DNA

1982 • 215 citations

Micro-homology mediated PCR targeting inSaccharomyces cerevisiae

1995 • 175 citations

Fused protein domains inhibit DNA binding by LexA.

1992 • 173 citations

Mutations in the MSH3 gene preferentially lead to deletions within tracts of simple repetitive DNA in Saccharomyces cerevisiae.

1995 • 147 citations

The yeast gene MSH3 defines a new class of eukaryotic MutS homologues

1993 • 140 citations

Single-Strand DNA-Specific Exonucleases in Escherichia coli: Roles in Repair and Mutation Avoidance

1998 • 138 citations

Functional Domains of the Saccharomyces cerevisiae Mlh1p and Pms1p DNA Mismatch Repair Proteins and Their Relevance to Human Hereditary Nonpolyposis Colorectal Cancer-Associated Mutations

1997 • 123 citations

Frameshift Intermediates in Homopolymer Runs Are Removed Efficiently by Yeast Mismatch Repair Proteins

1997 • 108 citations

Mutational specificity of the dnaE173 mutator associated with a defect in the catalytic subunit of DNA polymerase III of Escherichia coli

1991 • 77 citations

Fused Protein Domains Inhibit DNA Binding by LexA

1992 • 76 citations

Replication of the promiscuous plasmid pLSI: a region encompassing the minus origin of replication is associated with stable plasmid inheritance

1993 • 76 citations

Mismatch repair of cis-diamminedichloroplatinum(II)-induced DNA damage.

1985 • 74 citations

DNA repair in prokaryotes and lower eukaryotes

1998 • 56 citations

Dual requirement in yeast DNA mismatch repair for MLH1 and PMS1, two homologs of the bacterial mutL gene

1994 • 54 citations

Processing of O6-methylguanine by mismatch correction in human cell extracts

1996 • 45 citations

Differential effects of the mismatch repair genes MSH2 and MSH3 on homeologous recombination in Saccharomyces cerevisiae

1997 • 32 citations

Saccharomyces cerevisiae pms2 Mutations Are Alleles of MLH1, and pms2-2 Corresponds to a Hereditary Nonpolyposis Colorectal Carcinoma-Causing Missense Mutation

1996 • 11 citations