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WIP is critical for T cell responsiveness to IL-2

Data up to Jan 2025

Published2009
Citations25
References32

Total Citations Per Year

Abstract

References (32)

The WASP–WAVE protein network: connecting the membrane to the cytoskeleton

2006 • 915 citations

T cell– and B cell–independent adaptive immunity mediated by natural killer cells

2006 • 869 citations

Stat5 Is Required for IL-2-Induced Cell Cycle Progression of Peripheral T Cells

1999 • 554 citations

Wiskott-Aldrich Syndrome Protein-Deficient Mice Reveal a Role for WASP in T but Not B Cell Activation

1998 • 494 citations

Transcellular Diapedesis Is Initiated by Invasive Podosomes

2007 • 473 citations

The Wiskott-Aldrich syndrome

2006 • 409 citations

WIP, a protein associated with Wiskott–Aldrich syndrome protein, induces actin polymerization and redistribution in lymphoid cells

1997 • 376 citations

Antigen Receptor–Induced Activation and Cytoskeletal Rearrangement Are Impaired in Wiskott-Aldrich Syndrome Protein–Deficient Lymphocytes

1999 • 367 citations

Tracking STAT nuclear traffic

2006 • 349 citations

Opposing Effects of PKCθ and WASp on Symmetry Breaking and Relocation of the Immunological Synapse

2007 • 342 citations

WIP regulates N-WASP-mediated actin polymerization and filopodium formation

2001 • 280 citations

An Indirect Effect of Stat5a in IL-2–Induced Proliferation: A Critical Role for Stat5a in IL-2–Mediated IL-2 Receptor α Chain Induction

1997 • 275 citations

Mechanism of Recruitment of WASP to the Immunological Synapse and of Its Activation Following TCR Ligation

2002 • 261 citations

Defective Actin Reorganization and Polymerization of Wiskott-Aldrich T Cells in Response to CD3-Mediated Stimulation

1997 • 206 citations

T cells of patients with the Wiskott-Aldrich syndrome have a restricted defect in proliferative responses.

1993 • 197 citations

The interaction between Cdc42 and WASP is required for SDF-1–induced T-lymphocyte chemotaxis

2001 • 193 citations

WIP Deficiency Reveals a Differential Role for WIP and the Actin Cytoskeleton in T and B Cell Activation

2002 • 166 citations

WIP Regulates the Stability and Localization of WASP to Podosomes in Migrating Dendritic Cells

2006 • 124 citations

Impaired dendritic-cell homing in vivo in the absence of Wiskott-Aldrich syndrome protein

2004 • 121 citations

Differential Roles for Wiskott-Aldrich Syndrome Protein in Immune Synapse Formation and IL-2 Production

2004 • 117 citations

WIP and WASP play complementary roles in T cell homing and chemotaxis to SDF-1α

2005 • 94 citations

Impaired T-cell priming in vivo resulting from dysfunction of WASp-deficient dendritic cells

2007 • 90 citations

Expression of Wiskott-Aldrich Syndrome Protein in Dendritic Cells Regulates Synapse Formation and Activation of Naive CD8+ T Cells

2008 • 77 citations

Differential role of SLP-76 domains in T cell development and function

2002 • 73 citations

A role for the cytoskeleton in prolactin-dependent mammary epithelial cell differentiation

2003 • 54 citations

The expression of Wiskott-Aldrich syndrome protein (WASP) is dependent on WASP-interacting protein (WIP)

2006 • 43 citations

Efficient antigen presentation of soluble, but not particulate, antigen in the absence of Wiskott–Aldrich syndrome protein

2003 • 42 citations

Improvement of Migratory Defects in a Murine Model of Wiskott–Aldrich Syndrome Gene Therapy

2008 • 39 citations

A novel anti-WIP monoclonal antibody detects an isoform of WIP that lacks the WASP binding domain

2006 • 22 citations

A role for the cytoskeleton in STAT5 activation in MCF7 human breast cancer cells stimulated with EGF

2006 • 22 citations

Relative roles of T-cell receptor ligands and interleukin-2 in driving T-cell proliferation

2000 • 13 citations

Tubulin Polymerization Modulates Interleukin-2 Receptor Signal Transduction in Human T Cells

2006 • 7 citations

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WIP is critical for T cell responsiveness to IL-2 (2009) – Proceedings of the National Academy of Sciences | Metascience Observatory Explorer