WIP is critical for T cell responsiveness to IL-2
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References (32)
The WASP–WAVE protein network: connecting the membrane to the cytoskeleton
2006 • 915 citations
T cell– and B cell–independent adaptive immunity mediated by natural killer cells
2006 • 869 citations
Stat5 Is Required for IL-2-Induced Cell Cycle Progression of Peripheral T Cells
1999 • 554 citations
Wiskott-Aldrich Syndrome Protein-Deficient Mice Reveal a Role for WASP in T but Not B Cell Activation
1998 • 494 citations
Transcellular Diapedesis Is Initiated by Invasive Podosomes
2007 • 473 citations
The Wiskott-Aldrich syndrome
2006 • 409 citations
WIP, a protein associated with Wiskott–Aldrich syndrome protein, induces actin polymerization and redistribution in lymphoid cells
1997 • 376 citations
Antigen Receptor–Induced Activation and Cytoskeletal Rearrangement Are Impaired in Wiskott-Aldrich Syndrome Protein–Deficient Lymphocytes
1999 • 367 citations
Tracking STAT nuclear traffic
2006 • 349 citations
Opposing Effects of PKCθ and WASp on Symmetry Breaking and Relocation of the Immunological Synapse
2007 • 342 citations
WIP regulates N-WASP-mediated actin polymerization and filopodium formation
2001 • 280 citations
An Indirect Effect of Stat5a in IL-2–Induced Proliferation: A Critical Role for Stat5a in IL-2–Mediated IL-2 Receptor α Chain Induction
1997 • 275 citations
Mechanism of Recruitment of WASP to the Immunological Synapse and of Its Activation Following TCR Ligation
2002 • 261 citations
Defective Actin Reorganization and Polymerization of Wiskott-Aldrich T Cells in Response to CD3-Mediated Stimulation
1997 • 206 citations
T cells of patients with the Wiskott-Aldrich syndrome have a restricted defect in proliferative responses.
1993 • 197 citations
The interaction between Cdc42 and WASP is required for SDF-1–induced T-lymphocyte chemotaxis
2001 • 193 citations
WIP Deficiency Reveals a Differential Role for WIP and the Actin Cytoskeleton in T and B Cell Activation
2002 • 166 citations
WIP Regulates the Stability and Localization of WASP to Podosomes in Migrating Dendritic Cells
2006 • 124 citations
Impaired dendritic-cell homing in vivo in the absence of Wiskott-Aldrich syndrome protein
2004 • 121 citations
Differential Roles for Wiskott-Aldrich Syndrome Protein in Immune Synapse Formation and IL-2 Production
2004 • 117 citations
WIP and WASP play complementary roles in T cell homing and chemotaxis to SDF-1α
2005 • 94 citations
Impaired T-cell priming in vivo resulting from dysfunction of WASp-deficient dendritic cells
2007 • 90 citations
Expression of Wiskott-Aldrich Syndrome Protein in Dendritic Cells Regulates Synapse Formation and Activation of Naive CD8+ T Cells
2008 • 77 citations
Differential role of SLP-76 domains in T cell development and function
2002 • 73 citations
A role for the cytoskeleton in prolactin-dependent mammary epithelial cell differentiation
2003 • 54 citations
The expression of Wiskott-Aldrich syndrome protein (WASP) is dependent on WASP-interacting protein (WIP)
2006 • 43 citations
Efficient antigen presentation of soluble, but not particulate, antigen in the absence of Wiskott–Aldrich syndrome protein
2003 • 42 citations
Improvement of Migratory Defects in a Murine Model of Wiskott–Aldrich Syndrome Gene Therapy
2008 • 39 citations
A novel anti-WIP monoclonal antibody detects an isoform of WIP that lacks the WASP binding domain
2006 • 22 citations
A role for the cytoskeleton in STAT5 activation in MCF7 human breast cancer cells stimulated with EGF
2006 • 22 citations
Relative roles of T-cell receptor ligands and interleukin-2 in driving T-cell proliferation
2000 • 13 citations
Tubulin Polymerization Modulates Interleukin-2 Receptor Signal Transduction in Human T Cells
2006 • 7 citations
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