Progesterone Increases Tissue Factor Gene Expression, Procoagulant Activity, and Invasion in the Breast Cancer Cell Line ZR-75-1

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Menopausal Estrogen and Estrogen-Progestin Replacement Therapy and Breast Cancer Risk

2000 • 1,075 citations

Physiological Action of Progesterone in Target Tissues*

1997 • 912 citations

Differential Gene Regulation by the Two Progesterone Receptor Isoforms in Human Breast Cancer Cells

2002 • 566 citations

The Hypercoagulable State of Malignancy: Pathogenesis and Current Debate

2002 • 512 citations

Glucose transporters: expression, regulation and cancer

2002 • 443 citations

Establishment and characterization of three new continuous cell lines derived from human breast carcinomas.

1978 • 373 citations

[Establishment of a new human endometrial adenocarcinoma cell line, Ishikawa cells, containing estrogen and progesterone receptors].

1985 • 344 citations

Regulation of vascular endothelial growth factor production and angiogenesis by the cytoplasmic tail of tissue factor

1999 • 316 citations

Biphasic Regulation of Breast Cancer Cell Growth by Progesterone: Role of the Cyclin-Dependent Kinase Inhibitors, p21 and p27Kip1

1997 • 271 citations

Risks of breast and endometrial cancer after estrogen and estrogen-progestin replacement.

1999 • 263 citations

Caveolae: mining little caves for new cancer targets

2003 • 260 citations

Activation of coagulation and angiogenesis in cancer: immunohistochemical localization in situ of clotting proteins and vascular endothelial growth factor in human cancer.

1998 • 249 citations

Tissue factor expression in breast cancer tissues: its correlation with prognosis and plasma concentration

2000 • 237 citations

Vascular Endothelial Cell Growth Factor–Induced Tissue Factor Expression in Endothelial Cells Is Mediated by EGR-1

1999 • 215 citations

Ligand-induced protease receptor translocation into caveolae: a mechanism for regulating cell surface proteolysis of the tissue factor-dependent coagulation pathway.

1996 • 212 citations

Resveratrol, a Polyphenolic Compound Found in Wine, Inhibits Tissue Factor Expression in Vascular Cells

1999 • 200 citations

Tissue Factor in Health and Disease

1997 • 187 citations

Convergence of Progesterone with Growth Factor and Cytokine Signaling in Breast Cancer

1998 • 182 citations

Hypothesis: Progesterone Primes Breast Cancer Cells for Cross-Talk with Proliferative or Antiproliferative Signals

1999 • 176 citations

EGFR family signaling and its association with breast cancer development and resistance to chemotherapy (Review)

2003 • 175 citations

Sequence and detailed organization of the human caveolin‐1 and ‐2 genes located near the D7S522 locus (7q31.1)

1999 • 151 citations

Progestational regulation of human endometrial stromal cell tissue factor expression during decidualization.

1993 • 137 citations

Caveolin-1 down-regulates inducible nitric oxide synthase via the proteasome pathway in human colon carcinoma cells

2000 • 133 citations

Expression of tissue factor in tumor stroma correlates with progression to invasive human breast cancer: paracrine regulation by carcinoma cell-derived members of the transforming growth factor beta family.

1996 • 125 citations

The cytoplasmic domain of tissue factor is phosphorylated by a protein kinase C-dependent mechanism.

1992 • 125 citations

Enhanced expression of urokinase receptor induced through the tissue factor-factor VIIa pathway in human pancreatic cancer.

1998 • 113 citations

Identification of novel oestrogen receptor target genes in human ZR75-1 breast cancer cells by expression profiling

2001 • 113 citations

Antiapoptotic effect of coagulation factor VIIa

2003 • 103 citations

Norgestrel and gestodene stimulate breast cancer cell growth through an oestrogen receptor mediated mechanism

1993 • 98 citations

Tissue Factor Signaling

1999 • 70 citations

The epidermal growth factor receptor in breast cancer.

1997 • 64 citations

Association of smooth muscle cell tissue factor with caveolae

1996 • 63 citations

EGF-related peptides in the pathophysiology of the mammary gland.

1997 • 57 citations

Interferon-γ Modulates Prolactin and Tissue Factor Expression in Differentiating Human Endometrial Stromal Cells¹

2001 • 55 citations

Hormonal control of proliferation in the Ishikawa endometrial adenocarcinoma cell line

1990 • 54 citations

Estrogen and Progesterone Up-Regulate Glucose Transporter Expression in ZR-75-1 Human Breast Cancer Cells

2003 • 52 citations

The TF:VIIa Complex: Clinical Significance, Structure-function Relationships and Its Role in Signaling and Metastasis

2001 • 50 citations

The action of ovarian hormones in cardiovascular disease

2003 • 46 citations

Anticoagulants in thrombosis and cancer: the missing link

2002 • 45 citations

Effects of different progestin regimens in hormone replacement therapy on blood coagulation factor VII and tissue factor pathway inhibitor

2002 • 42 citations

Epidermal growth factor: receptor and ligand expression in human breast cancer.

1990 • 39 citations

Expression of tissue factor is associated with clinical features and angiogenesis in prostate cancer.

2003 • 39 citations

Plasma Membrane Receptors for the Cancer-Regulating Progesterone Metabolites, 5α-Pregnane-3,20-dione and 3α-Hydroxy-4-pregnen-20-one in MCF-7 Breast Cancer Cells

2000 • 36 citations

Estrous cycle influences organ-specific metastasis of B16F10 melanoma cells.

2003 • 33 citations

Post-translational modifications of recombinant human tissue factor

1990 • 32 citations

The structure and function of progesterone receptors in breast cancer

1987 • 29 citations

Different effect induced by treatment with several statins on monocyte tissue factor expression in hypercholesterolemic subjects

2003 • 25 citations

Protein expression profiles of non-small cell lung carcinomas: correlation with histological subtype.

2002 • 16 citations

Localization of tissue factor pathway inhibitor to lipid rafts is not required for inhibition of factor VIIa/tissue factor activity

2003 • 16 citations

Relationship between tissue factor expression and hepatic metastasis and prognosis in rectal cancer.

2002 • 4 citations