Fractals and cancer.

The Fractal Geometry of Nature

1983 • 22,064 citations

Introduction to Percolation Theory

1993 • 7,040 citations

Patterns and Emerging Mechanisms of the Angiogenic Switch during Tumorigenesis

1996 • 6,878 citations

Endostatin: An Endogenous Inhibitor of Angiogenesis and Tumor Growth

1997 • 4,504 citations

Mechanisms of angiogenesis and arteriogenesis

2000 • 4,120 citations

The Fourth Dimension of Life: Fractal Geometry and Allometric Scaling of Organisms

1999 • 1,696 citations

Interstitial pH and pO2 gradients in solid tumors in vivo: High-resolution measurements reveal a lack of correlation

1997 • 1,590 citations

Applications of Percolation Theory

1900 • 1,070 citations

Barriers to Drug Delivery in Solid Tumors

1994 • 1,064 citations

Tumor Induction of VEGF Promoter Activity in Stromal Cells

1998 • 964 citations

Diffusion-controlled cluster formation in 2—6-dimensional space

1983 • 651 citations

Spectrum of tumor angiogenesis in the bone marrow of children with acute lymphoblastic leukemia.

1997 • 546 citations

Microvascular architecture in a mammary carcinoma: branching patterns and vessel dimensions.

1991 • 505 citations

Genetic Control of Branching Morphogenesis

1999 • 499 citations

Is the Geometry of Nature Fractal?

1998 • 425 citations

The next frontier of molecular medicine: Delivery of therapeutics

1998 • 408 citations

Quantitative angiogenesis assays: Progress and problems

1997 • 386 citations

Endothelial cell death, angiogenesis, and microvascular function after castration in an androgen-dependent tumor: Role of vascular endothelial growth factor

1998 • 378 citations

FRACTALS IN PATHOLOGY

1997 • 301 citations

Self-organization, complexity and chaos: The new biology for medicine

1998 • 286 citations

Role of Tumor Vascular Architecture in Nutrient and Drug Delivery: An Invasion Percolation-Based Network Model

1996 • 271 citations

The Limited Scaling Range of Empirical Fractals

1998 • 256 citations

Characterisation of mammographic parenchymal pattern by fractal dimension

1990 • 232 citations

Scale-Invariant Behavior and Vascular Network Formation in Normal and Tumor Tissue

1995 • 222 citations

Fractal Characteristics of Tumor Vascular Architecture During Tumor Growth and Regression

1997 • 210 citations

The fractal properties of retinal vessels: Embryological and clinical implications

1990 • 206 citations

Analysis of oxygen transport to tumor tissue by microvascular networks

1993 • 199 citations

Oxygenation of Human Tumors

2000 • 189 citations

Nuclear texture measurements in image cytometry.

1995 • 155 citations

Quantitative classification of breast tumors in digitized mammograms

1996 • 154 citations

Symmetry of projection in the quantitative analysis of mammographic images

1996 • 151 citations

Establishing a Link between Oncogenes and Tumor Angiogenesis

1998 • 148 citations

The fractal dimension of the minimum path in two- and three-dimensional percolation

1988 • 137 citations

Lie detection and language comprehension

2000 • 124 citations

Shape analysis for classification of malignant melanoma

1992 • 116 citations

A Novel Assay of Angiogenesis in the Quail Chorioallantoic Membrane: Stimulation by bFGF and Inhibition by Angiostatin According to Fractal Dimension and Grid Intersection

1998 • 114 citations

Topological properties of diffusion limited aggregation and cluster-cluster aggregation

1984 • 113 citations

Basic Fribroblast Growth Factor Overexpression in Endothelial Cells: An Autocrine Mechanism for Angiogenesis and Angioproliferative Diseases

1998 • 109 citations

Geometric Resistance and Microvascular Network Architecture of Human Colorectal Carcinoma

1997 • 108 citations

A fractal approach to the segmentation of microcalcifications in digital mammograms

1995 • 105 citations

Fractal dimensions of the epithelial-connective tissue interfaces in premalignant and malignant epithelial lesions of the floor of the mouth.

1993 • 97 citations

The fractal geometry of proliferative diabetic retinopathy: implications for the diagnosis and the process of retinal vasculogenesis

1993 • 91 citations

Characterisation of the neovascularisation process in diabetic retinopathy by means of fractal geometry: diagnostic implications

1993 • 86 citations

Fractal analysis of the normal human retinal fluorescein angiogram

1993 • 77 citations

The Earth's Elements

1994 • 57 citations

Cryospectrophotometric Determination of Tumor Intravascular Oxyhemoglobin Saturations: Dependence on Vascular Geometry and Tumor Growth

1988 • 50 citations

Molecular determinants of angiogenesis in cancer metastasis.

1998 • 48 citations

Fractal tumours: their real and virtual images.

1996 • 40 citations

Fractal Quantification of the Microvasculature Heterogeneity in Cutaneous Melanoma

1999 • 35 citations

Fractals and Multifractals: The Interplay of Physics and Geometry

1991 • 34 citations

Toward objective prognostic grading of prostatic carcinoma using image analysis.

1993 • 32 citations

Vascular morphometry of KHT and RIF-1 murine sarcomas

1993 • 30 citations

Fractals in pathology: are they really useful?

1995 • 30 citations

Asymptotic fractals in the context of grey‐scale images

1998 • 29 citations

Steroid hormones modify nuclear heterochromatin structure and plasma membrane enzyme of MCF-7 cells. A combined fractal, electron microscopical and enzymatic analysis.

1998 • 27 citations

A breast density index for digital mammograms based on radiologists’ randing

1998 • 25 citations

Fractal tumor stromal border in a nonequilibrium growth model.

1998 • 23 citations

Dynamic Contrast-Enhanced MRI and Fractal Characteristics of Percolation Clusters in Two-Dimensional Tumor Blood Perfusion

1999 • 23 citations

Fractal analysis of mammographic lesions: A prospective, blinded trial

1998 • 23 citations

Classification of Lung Tumors on Chest Radiographs by Fractal Texture Analysis

1996 • 21 citations

Distribution of gland-like structures in human gallbladder adenocarcinomas possesses fractal dimension

1999 • 18 citations

Corneal vascularisation and its relation to the physical properties of the tissue: a fractal analysis

1995 • 14 citations

Fractal dimension of the bone marrow in metastatic lesions

1998 • 11 citations

[Fractal analysis of a breast carcinoma--presentation of a modern morphometric method].

1998 • 8 citations