Ligand-Specific Dynamics of the Progesterone Receptor in Living Cells and during Chromatin Remodeling In Vitro

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A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

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Estrogen Receptor-α Directs Ordered, Cyclical, and Combinatorial Recruitment of Cofactors on a Natural Target Promoter

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The Glucocorticoid Receptor: Rapid Exchange with Regulatory Sites in Living Cells

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Cyclic, Proteasome-Mediated Turnover of Unliganded and Liganded ERα on Responsive Promoters Is an Integral Feature of Estrogen Signaling

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Protein Dynamics: Implications for Nuclear Architecture and Gene Expression

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A human homologue of Saccharomyces cerevisiae SNF2/SWI2 and Drosophila brm genes potentiates transcriptional activation by the glucocorticoid receptor.

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Roles of SWI1, SWI2, and SWI3 Proteins for Transcriptional Enhancement by Steroid Receptors

1992 • 477 citations

Disassembly of Transcriptional Regulatory Complexes by Molecular Chaperones

2002 • 402 citations

The Opposing Transcriptional Activities of the Two Isoforms of the Human Progesterone Receptor Are Due to Differential Cofactor Binding

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High-Mobility Group Chromatin Proteins 1 and 2 Functionally Interact with Steroid Hormone Receptors To Enhance Their DNA Binding In Vitro and Transcriptional Activity in Mammalian Cells

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Nuclear receptors coordinate the activities of chromatin remodeling complexes and coactivators to facilitate initiation of transcription

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Rapid Glucocorticoid Receptor Exchange at a Promoter Is Coupled to Transcription and Regulated by Chaperones and Proteasomes

2004 • 261 citations

Rapid Periodic Binding and Displacement of the Glucocorticoid Receptor during Chromatin Remodeling

2004 • 234 citations

Dynamic behavior of transcription factors on a natural promoter in living cells

2002 • 214 citations

Unfolding the Action of Progesterone Receptors

2003 • 207 citations

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Two types of antiprogestins identified by their differential action in transcriptionally active extracts from T47D cells

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1995 • 171 citations

Ligand-dependent interaction between the estrogen receptor and the human homologues of SWI2/SNF2

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Coactivator/corepressor ratios modulate PR-mediated transcription by the selective receptor modulator RU486

2002 • 157 citations

Ligand-Mediated Assembly and Real-Time Cellular Dynamics of Estrogen Receptor α-Coactivator Complexes in Living Cells

2001 • 150 citations

Differential Localization and Activity of the A- and B-Forms of the Human Progesterone Receptor Using Green Fluorescent Protein Chimeras

1999 • 149 citations

Mammalian SWI-SNF Complexes Contribute to Activation of the hsp70 Gene

2000 • 149 citations

Mechanism of Action of Progesterone Antagonists

2002 • 142 citations

Molecular chaperones function as steroid receptor nuclear mobility factors

2004 • 141 citations

ATP-Dependent Mobilization of the Glucocorticoid Receptor during Chromatin Remodeling

2002 • 137 citations

Transcription Factors and Nuclear Receptors Interact with the SWI/SNF Complex through the BAF60c Subunit

2004 • 134 citations

Nuclear Receptors

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Differential Requirement of SWI/SNF for Androgen Receptor Activity

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Using Inducible Vectors to Study Intracellular Trafficking of GFP-Tagged Steroid/Nuclear Receptors in Living Cells

1999 • 101 citations

Dynamics of nuclear receptor movement and transcription

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Structure and Dynamic Properties of a Glucocorticoid Receptor-Induced Chromatin Transition

2000 • 90 citations

Progesterone receptor and the mechanism of action of progesterone antagonists

1995 • 87 citations

The Affinity of Nuclear Factor 1 for Its DNA Site Is Drastically Reduced by Nucleosome Organization Irrespective of Its Rotational or Translational Position

1996 • 80 citations

The Activity of Mammalian brm/SNF2α Is Dependent on a High-Mobility-Group Protein I/Y-Like DNA Binding Domain

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Antiprogestins prevent progesterone receptor binding to hormone responsive elements in vivo.

1994 • 60 citations

The Position and Length of the Steroid-Dependent Hypersensitive Region in the Mouse Mammary Tumor Virus Long Terminal Repeat Are Invariant despite Multiple Nucleosome B Frames

1998 • 56 citations

In vivo evidence against the existence of antiprogestins disrupting receptor binding to DNA.

1993 • 55 citations

The Antagonists RU486 and ZK98299 Stimulate Progesterone Receptor Binding to Deoxyribonucleic Acid in Vitro and in Vivo, but Have Distinct Effects on Receptor Conformation*

1998 • 53 citations

Effects of the steroid antagonist RU486 on dimerization of the human progesterone receptor

1992 • 52 citations

Understanding nuclear receptor function: From DNA to chromatin to the interphase nucleus

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Dissection of progesterone receptor-mediated chromatin remodeling and transcriptional activation in vivo.

1995 • 45 citations

Assembly of MMTV promoter minichromosomes with positioned nucleosomes precludes NF1 access but not restriction enzyme cleavage

1998 • 32 citations

Glucocorticoid action : basic and clinical implications

2004 • 4 citations