Dissection of progesterone receptor-mediated chromatin remodeling and transcriptional activation in vivo.

The Steroid and Thyroid Hormone Receptor Superfamily

1988 • 7,590 citations

NUCLEASE HYPERSENSITIVE SITES IN CHROMATIN

1988 • 1,233 citations

The 5′ ends of Drosophila heat shock genes in chromatin are hypersensitive to DNase I

1980 • 1,114 citations

Chromatin as an essential part of the transcriptional mechanim

1992 • 853 citations

Stimulation of GAL4 Derivative Binding to Nucleosomal DNA by the Yeast SWI/SNF Complex

1994 • 853 citations

A novel rapid assay for chloramphenicol acetyltransferase gene expression

1987 • 802 citations

A human homologue of Saccharomyces cerevisiae SNF2/SWI2 and Drosophila brm genes potentiates transcriptional activation by the glucocorticoid receptor.

1993 • 598 citations

Sequence-specific positioning of nucleosomes over the steroid-inducible MMTV promoter.

1987 • 597 citations

Evidence that SNF2/SWI2 and SNF5 activate transcription in yeast by altering chromatin structure.

1992 • 535 citations

Roles of SWI1, SWI2, and SWI3 Proteins for Transcriptional Enhancement by Steroid Receptors

1992 • 477 citations

Reversible and persistent changes in chromatin structure accompany activation of a glucocorticoid-dependent enhancer element

1984 • 449 citations

Steroid-dependent interaction of transcription factors with the inducible promoter of mouse mammary tumor virus in vivo

1987 • 448 citations

A 200 base pair region at the 5$prime; end of the chicken adult $beta;-globin gene is accessible to nuclease digestion

1981 • 443 citations

Glucocorticoid receptor mutants that are constitutive activators of transcriptional enhancement

1987 • 428 citations

Transcription Factor Loading on the MMTV Promoter: A Bimodal Mechanism for Promoter Activation

1992 • 411 citations

The formation and function of DNase I hypersensitive sites in the process of gene activation.

1988 • 394 citations

Transcription factor access is mediated by accurately positioned nucleosomes on the mouse mammary tumor virus promoter.

1991 • 372 citations

Glucocorticoid and progesterone receptors bind to the same sites in two hormonally regulated promoters

1985 • 366 citations

Two human homologues ofSaccharomyces cerevisiae SWI2/SNF2andDrosophila brahmaare transcriptional coactivators cooperating with the estrogen receptor and the retinoic acid receptor

1994 • 338 citations

Nuclease hypersensitive regions with adjacent positioned nucleosomes mark the gene boundaries of the PHO5/PHO3 locus in yeast.

1986 • 254 citations

Transcription: In tune with the histones

1994 • 239 citations

Multiple functions of nucleosomes and regulatory factors in transcription

1993 • 187 citations

Nucleosomes: regulators of transcription

1990 • 186 citations

New steroids with antiprogestational and antiglucocorticoid activities

1984 • 182 citations

Two types of antiprogestins identified by their differential action in transcriptionally active extracts from T47D cells

1991 • 182 citations

Activation of globin genes during chicken development

1981 • 164 citations

Yeast SNF2/SWI2, SNF5, and SNF6 proteins function coordinately with the gene-specific transcriptional activators GAL4 and Bicoid.

1992 • 157 citations

Nucleosome-mediated disruption of transcription factor-chromatin initiation complexes at the mouse mammary tumor virus long terminal repeat in vivo.

1994 • 128 citations

Hormone-induced progesterone receptor phosphorylation consists of sequential DNA-independent and DNA-dependent stages: analysis with zinc finger mutants and the progesterone antagonist ZK98299.

1992 • 119 citations

Ligand-dependent conformational changes in the progesterone receptor are necessary for events that follow DNA binding.

1992 • 108 citations

Chromatin structure and gene activity

1990 • 100 citations

The steroid antagonist RU486 exerts different effects on the glucocorticoid and progesterone receptors.

1993 • 88 citations

Nucleosome Disruption by Transcription Factor Binding in Yeast

1993 • 87 citations

Differential steroid hormone induction of transcription from the mouse mammary tumor virus promoter.

1994 • 87 citations

A Quantitative Comparison of Dual Control of a Hormone Response Element by Progestins and Glucocorticoids in the Same Cell Line

1989 • 80 citations

The differential capacity of glucocorticoids and progestins to alter chromatin structure and induce gene expression in human breast cancer cells.

1994 • 65 citations

Antiprogestins prevent progesterone receptor binding to hormone responsive elements in vivo.

1994 • 60 citations

Type II antagonists impair the DNA binding of steroid hormone receptors without affecting dimerization

1993 • 45 citations

Mouse Mammary Tumor Virus Chromatin in Human Breast Cancer Cells Is Constitutively Hypersensitive and Exhibits Steroid Hormone-Independent Loading of Transcription Factors In Vivo

1995 • 44 citations

The steroid antagonist RU486 exerts different effects on the glucocorticoid and progesterone receptors

1993 • 36 citations

Steroid Transactivation at a Promoter Organized in a Specifically-Positioned Array of Nucleosomes

1989 • 36 citations

Differential steroid hormone induction of transcription from the mouse mammary tumor virus promoter

1994 • 34 citations

The differential capacity of glucocorticoids and progestins to alter chromatin structure and induce gene expression in human breast cancer cells

1994 • 24 citations

ZK98299—A new antiprogesterone: Biochemical characterization of steroid binding parameters in the calf uterine cytosol

1992 • 19 citations

Detection of transcription factor bindingin vivousing lambda exonuclease

1994 • 16 citations

The First Hundred Years

1989 • 10 citations