Multiple Organ Dysfunction Syndrome in Bone Marrow Transplantation

Definitions for Sepsis and Organ Failure and Guidelines for the Use of Innovative Therapies in Sepsis

1992 • 12,726 citations

Quantitative estimation of proteins by electrophoresis in agarose gel containing antibodies

1966 • 4,504 citations

The Pathogenesis of Sepsis

1991 • 1,376 citations

Multiple-Organ Failure

1985 • 1,314 citations

Prognosis in Acute Organ-System Failure

1985 • 1,248 citations

Veno-occlusive Disease of the Liver and Multiorgan Failure after Bone Marrow Transplantation: A Cohort Study of 355 Patients

1993 • 1,173 citations

Plasma Cytokine and Endotoxin Levels Correlate with Survival in Patients with the Sepsis Syndrome

1993 • 1,068 citations

Venocclusive Disease of the Liver after Bone Marrow Transplantation: Diagnosis, Incidence, and Predisposing Factors

1984 • 845 citations

Protein C prevents the coagulopathic and lethal effects of Escherichia coli infusion in the baboon.

1987 • 836 citations

Septic Shock, Multiple Organ Failure, and Disseminated Intravascular Coagulation

1992 • 708 citations

Increased serum levels of tumor necrosis factor alpha precede major complications of bone marrow transplantation [see comments]

1990 • 591 citations

Multiple Organ Failure Syndrome in the 1990s

1994 • 532 citations

Multiple Organ Failure in Polytrauma Patients

1983 • 492 citations

Role of tumor necrosis factor-α in disease states and inflammation

1993 • 415 citations

Double-blind, Placebo-controlled Trial of Antithrombin III Concentrates in Septic Shock With Disseminated Intravascular Coagulation

1993 • 379 citations

Idiopathic Pneumonia Syndrome after Bone Marrow Transplantation

1993 • 327 citations

Time Course of Hemostatic Abnormalities in Sepsis and its Relation to Outcome

1993 • 310 citations

Tumor necrosis factor: an updated review of its biology.

1993 • 284 citations

Inflammation and Coagulation: Linked Processes Potentially Regulated Through a Common Pathway Mediated by Protein C

1991 • 261 citations

High-dose therapy and autologous peripheral blood stem cell transplantation for patients with lymphoma

1989 • 243 citations

DEGR-factor Xa blocks disseminated intravascular coagulation initiated by Escherichia coli without preventing shock or organ damage

1991 • 216 citations

The quantitative association of plasma endotoxin, antithrombin, protein C, extrinsic pathway inhibitor and fibrinopeptide a in systemic meningococcal disease

1989 • 172 citations

Adult Respiratory Distress Syndrome

1992 • 161 citations

Coagulation, fibrinolysis, and kallikrein systems in sepsis

1989 • 159 citations

Fast functional protein C assay using protac® a novel protein C activator

1986 • 146 citations

Protein C, protein S and C4b-binding protein in severe infection and septic shock.

1991 • 145 citations

Antithrombin-III prevents the lethal effects of Escherichia coli infusion in baboons.

1988 • 142 citations

Meningococcemia and purpura fulminans in adults: acute deficiencies of proteins C and S and early treatment with antithrombin III concentrates

1990 • 138 citations

Modulators of coagulation. A critical appraisal of their role in sepsis

1992 • 124 citations

Autologous bone marrow transplantation for patients with relapsed hodgkin's disease

1991 • 114 citations

Multiple organ failure syndrome in the 1990s

1995 • 113 citations

The Hypermetabolism

1989 • 95 citations

The Natural History of Major Burns with Multiple Subsystem Failure

1983 • 90 citations

Activation of the contact system of plasma proteolysis in the adult respiratory distress syndrome.

1988 • 89 citations

Naturally occurring anticoagulants and bone marrow transplantation: plasma protein C predicts the development of venocclusive disease of the liver

1993 • 89 citations

On the reliability of clinical criteria for the diagnosis of hepatic veno-occlusive disease

1993 • 84 citations

Therapeutic efficacy of autologous blood stem cell transplantation (ABSCT): the role of cytotoxic/cytokine stem cell mobilization.

1990 • 81 citations

Hepatic venoocclusive disease in autologous bone marrow transplantation of solid tumors and lymphomas.

1990 • 72 citations

Risk Factors for Multiorgan Failure

1991 • 71 citations

Reduction of Mortality with Antithrombin III in Septicemic Rats: A Study of Klebsiella pneumoniae Induced Sepsis

1993 • 70 citations

Microvasculopathy in the Ocular Fundus after Bone Marrow Transplantation

1991 • 70 citations

Perioperative TNF alpha and IL-6 concentrations correlate with septic state, organ function, and APACHE II scores in intra-abdominal infection.

1993 • 58 citations

Plasma Prekallikrein, Factor XII, Antithrombin III, C1−-Inhibitor and α2-Macroglobulin in Critically III Patients with Suspected Disseminated Intravascular Coagulation (DIC)

1984 • 55 citations

Protein S and C alterations in acutely III patients

1991 • 45 citations

Protection against disseminated intravascular coagulation and death by antithrombin-III in the Escherichia coli endotoxemic rat.

1987 • 45 citations

Antithrombin III deficiency in surgical intensive care patients

1981 • 37 citations

ANTITHROMBIN III AND TRAUMA PATIENTS

1994 • 34 citations

Differences in coagulation and fibrinolysis after traumatic and septic shock in man

1989 • 32 citations

Autologous bone marrow transplantation and factor xii, factor vii, and protein c deficiencies report of a new association and its possible relationship to endothelial cell injury

1990 • 31 citations

Synergistic protection from lung damage by combining antithrombin-III and alpha 1-proteinase inhibitor in the E. coli endotoxemic sheep pulmonary dysfunction model.

1988 • 28 citations

Thrombotic complications of BMT: association with protein C deficiency.

1993 • 24 citations

The Value of Variables of Disseminated Intravascular Coagulation in the Diagnosis of Adult Respiratory Distress Syndrome

1983 • 20 citations

Changes in the fibrinolysin system in infantile and adult respiratory distress syndrome (ARDS), caused by trauma and/or septic shock in patients and in experimental animals.

1990 • 14 citations

Two automated methods for plasma antithrombin III compared, and the clinical significance of the results.

1982 • 5 citations

Antithrombin III and early prognosis in polytraumatized patients: A pilot study

1991 • 3 citations