Interstitial Collagenase (MMP-1) Expression in Human Carotid Atherosclerosis

The pathogenesis of atherosclerosis: a perspective for the 1990s

1993 • 10,730 citations

Plaque fissuring--the cause of acute myocardial infarction, sudden ischaemic death, and crescendo angina.

1985 • 2,003 citations

Site of intimal rupture or erosion of thrombosed coronary atherosclerotic plaques is characterized by an inflammatory process irrespective of the dominant plaque morphology.

1994 • 1,913 citations

Thrombosis and Acute Coronary-Artery Lesions in Sudden Cardiac Ischemic Death

1984 • 1,700 citations

A monoclonal antibody against alpha-smooth muscle actin: a new probe for smooth muscle differentiation.

1986 • 1,644 citations

INFLUENCE OF PLAQUE CONFIGURATION AND STRESS DISTRIBUTION ON FISSURING OF CORONARY ATHEROSCLEROTIC PLAQUES

1989 • 1,249 citations

Risk of thrombosis in human atherosclerotic plaques: role of extracellular lipid, macrophage, and smooth muscle cell content.

1993 • 1,132 citations

Macrophage infiltration in acute coronary syndromes. Implications for plaque rupture.

1994 • 1,125 citations

Hypothesis: Vasa Vasorum and Neovascularization of Human Coronary Arteries

1984 • 852 citations

Vascular cell adhesion molecule-1 is expressed in human coronary atherosclerotic plaques. Implications for the mode of progression of advanced coronary atherosclerosis.

1993 • 709 citations

12-O-tetradecanoyl-phorbol-13-acetate induction of the human collagenase gene is mediated by an inducible enhancer element located in the 5'-flanking region.

1987 • 699 citations

Human atherosclerosis. II. Immunocytochemical analysis of the cellular composition of human atherosclerotic lesions.

1986 • 676 citations

Effects of fibrous cap thickness on peak circumferential stress in model atherosclerotic vessels.

1992 • 667 citations

Human fibroblast collagenase. Complete primary structure and homology to an oncogene transformation-induced rat protein.

1986 • 645 citations

Cytokine-stimulated human vascular smooth muscle cells synthesize a complement of enzymes required for extracellular matrix digestion.

1994 • 644 citations

Requirement for fos gene expression in the transcriptional activation of collagenase by other oncogenes and phorbol esters

1988 • 597 citations

Localization of stromelysin gene expression in atherosclerotic plaques by in situ hybridization.

1991 • 593 citations

Localization of PDGF-B Protein in Macrophages in All Phases of Atherogenesis

1990 • 584 citations

Tissue cooperation in a proteolytic cascade activating human interstitial collagenase.

1989 • 579 citations

Ulex europaeus I lectin as a marker for vascular endothelium in human tissues.

1982 • 573 citations

The natural history of carotid arterial disease in asymptomatic patients with cervical bruits.

1984 • 521 citations

Stromelysin, a connective tissue-degrading metalloendopeptidase secreted by stimulated rabbit synovial fibroblasts in parallel with collagenase. Biosynthesis, isolation, characterization, and substrates.

1985 • 506 citations

Stromelysin is an activator of procollagenase. A study with natural and recombinant enzymes

1987 • 474 citations

Neutral metalloproteinases produced by human mononuclear phagocytes. Enzyme profile, regulation, and expression during cellular development.

1990 • 459 citations

Mechanisms of activation of tissue procollagenase by matrix metalloproteinase 3 (stromelysin)

1990 • 431 citations

The Importance of Hemorrhage in the Relationship Between Gross Morphologic Characteristics and Cerebral Symptoms in 376 Carotid Artery Plaques

1983 • 279 citations

The Role of Plasmhogen Activators in the Regulation of Connective Tissue Metalloproteinasesa

1992 • 243 citations

Proteinases and extracellular remodeling

1989 • 224 citations

Immunohistochemical study of intimal microvessels in coronary atherosclerosis.

1993 • 203 citations

Collagens in human atherosclerosis. Immunohistochemical analysis using collagen type-specific antibodies.

1992 • 203 citations

The interaction of α2-macroglobulin with proteinases. Binding and inhibition of mammalian collagenases and other metal proteinases

1974 • 202 citations

Lipoprotein lipase is synthesized by macrophage-derived foam cells in human coronary atherosclerotic plaques.

1992 • 200 citations

Human alveolar macrophages produce a fibroblast-like collagenase and collagenase inhibitor.

1985 • 199 citations

Tumor necrosis factor gene expression in human vascular intimal smooth muscle cells detected by in situ hybridization.

1990 • 184 citations

The activation of human skin fibroblast procollagenase. Sequence identification of the major conversion products.

1987 • 173 citations

Distinct localization of collagenase and tissue inhibitor of metalloproteinases expression in wound healing associated with ulcerative pyogenic granuloma.

1992 • 167 citations

Collagen types I and III, collagen content, GAGs and mechanical strength of human atherosclerotic plaque caps: span-wise variations

1992 • 159 citations

Heparin inhibits the induction of three matrix metalloproteinases (stromelysin, 92-kD gelatinase, and collagenase) in primate arterial smooth muscle cells.

1994 • 124 citations

Localization of mRNAs representing collagenase and TIMP in sections of healing human burn wounds.

1993 • 95 citations

Production of tissue collagenase (matrix metalloproteinase 1) by human aortic smooth muscle cells in response to platelet-derived growth factor

1991 • 91 citations

Interleukin-1 gene expression in rabbit vascular tissue in vivo.

1991 • 84 citations

Enzyme-Linked Immunosorbent Assay for Human Skin Collagenase

1983 • 82 citations

Production of latent collagenase by human umbilical vein endothelial cells in response to angiogenic preparations

1985 • 38 citations

Clinical relevance of intraplaque hemorrhage in the internal carotid artery.

1991 • 29 citations