Opioid-receptor mRNA expression in the rat CNS: anatomical and functional implications

The effects of morphine- and nalorphine- like drugs in the nondependent and morphine-dependent chronic spinal dog.

1976 • 2,883 citations

Opiate Receptor: Demonstration in Nervous Tissue

1973 • 2,364 citations

Cloning of a Delta Opioid Receptor by Functional Expression

1992 • 1,225 citations

Anatomy of CNS opioid receptors

1988 • 1,178 citations

Opposite effects of mu and kappa opiate agonists on dopamine release in the nucleus accumbens and in the dorsal caudate of freely moving rats.

1988 • 913 citations

Brainstem Control of Spinal Pain-Transmission Neurons

1978 • 820 citations

Narcotic analgetics: CNS sites and mechanisms of action as revealed by intracerebral injection techniques

1977 • 656 citations

Stereospecific Interaction Between Narcotic Analgesics and a Synaptic Plasma Membrane Fraction of Rat Cerebral Cortex

1973 • 650 citations

Cloning and pharmacological characterization of a rat μ opioid receptor

1993 • 460 citations

Multiple opioid receptors: ligand selectivity profiles and binding site signatures.

1989 • 441 citations

Molecular biology of opioid receptors

1993 • 358 citations

Enkephalin blocks inhibitory pathways in the vertebrate CNS

1980 • 334 citations

μ-Opioid receptor mRNA expression in the rat CNS: comparison to μ-receptor binding

1994 • 298 citations

SPECTRUM OF THE μ‐, δ‐ AND κ‐BINDING SITES IN HOMOGENATES OF RAT BRAIN

1982 • 278 citations

κ and δ-opioid receptor agonists differentially inhibit striatal dopamine and acetylcholine release

1984 • 275 citations

Opioid Receptors Undergo Axonal Flow

1980 • 274 citations

Anatomically Distinct Opiate Receptor Fields Mediate Reward and Physical Dependence

1984 • 265 citations

Expression of Mu opioid receptor mRNA in rat brain: An in situ hybridization study at the single cell level

1994 • 213 citations

Site-directed alkylation of multiple opioid receptors. I. Binding selectivity.

1984 • 200 citations

Evidence that the aversive effects of opioid antagonists and ?-agonists are centrally mediated

1989 • 193 citations

Autoradiographic localization of μ- and δ-opiate receptors in the forebrain of the rat

1986 • 170 citations

Motivational properties of opioids: evidence that an activation of σ-receptors mediates reinforcement processes

1987 • 167 citations

Immunofluorescent indentification of a delta (δ)-opioid receptor on primary afferent nerve terminals

1993 • 162 citations

κ1 Receptor mRNA Distribution in the Rat CNS: Comparison to κ Receptor Binding and Prodynorphin mRNA

1994 • 152 citations

Delta opioid receptor mRNA distribution in the brain: Comparison to delta receptor binding and proenkephalin mRNA

1993 • 143 citations

μ-, δ- and κ-opioid receptor-mediated inhibition of neurotransmitter release and adenylate cyclase activity in rat brain slices: studies with fentanyl isothiocyanate

1988 • 132 citations

Studies on the nature and mechanism of the diuretic activity of the opioid analgesic ethylketocyclazocine.

1982 • 112 citations

Effects of Specific Activation of Mu-, Delta- and Kappa-Opioid Receptors on the Secretion of Luteinizing Hormone and Prolactin in the Ovariectomized Rat

1987 • 103 citations

The actions of opiates in the rat substantia nigra: An electrophysiological analysis

1983 • 76 citations

In situ hybridization study of μ- and κ-opioid receptor mRNAs in the rat spinal cord and dorsal root ganglia

1994 • 74 citations

Morphine and Enkephalins Potently Inhibit [³H]Noradrenaline Release from Rat Brain Cortex Synaptosomes: Further Evidence for a Presynaptic Localization of μ‐Opioid Receptors

1987 • 52 citations

CENTRAL KAPPA- AND MU-OPIATE RECEPTORS MEDIATE ACTH-RELEASE IN RATS.

1985 • 49 citations

Localization of κ-opioid receptor mRNA in neuronal subpopulations of rat sensory ganglia and spinal cord

1994 • 49 citations

Time-related decreases in μ and δ opioid receptors in the superficial dorsal horn of the rat spinal cord following a large unilateral dorsal rhizotomy

1992 • 47 citations