U4 small nuclear RNA dissociates from a yeast spliceosome and does not participate in the subsequent splicing reaction.

Molecular cloning: A laboratory manual

1990 • 85,659 citations

SPLICING OF MESSENGER RNA PRECURSORS

1986 • 1,233 citations

Splicing of Messenger RNA Precursors

1987 • 919 citations

The role of small nuclear ribonucleoprotein particles in pre-mRNA splicing

1987 • 594 citations

Messenger RNA Splicing in Yeast: Clues to Why the Spliceosome Is a Ribonucleoprotein

1991 • 433 citations

Spliceosomal RNA U6 is remarkably conserved from yeast to mammals

1988 • 428 citations

Spliceosome assembly in yeast.

1987 • 402 citations

Identification of functional U1 snRNA-pre-mRNA complexes committed to spliceosome assembly and splicing

1989 • 391 citations

Structure and Function of Major and Minor Small Nuclear Ribonucleoprotein Particles

1988 • 363 citations

Yeast mRNA splicing in vitro.

1985 • 337 citations

Functions of the Abundant U-snRNPs

1988 • 284 citations

Electrophoresis of ribonucleoproteins reveals an ordered assembly pathway of yeast splicing complexes

1986 • 283 citations

An Early Hierarchic Role of U1 Small Nuclear Ribonucleoprotein in Spliceosome Assembly

1988 • 271 citations

U4 and U6 RNAs coexist in a single small nuclear ribonucleoprotein particle

1984 • 238 citations

Pre-mRNA splicing in vitro requires intact U4/U6 small nuclear ribonucleoprotein

1986 • 222 citations

Evidence for the existence of snRNAs U4 and U6 in a single ribonucleoprotein complex and for their association by intermolecular base pairing.

1984 • 213 citations

Pre-mRNA Splicing in Yeast

1989 • 209 citations

The effect of temperature-sensitive RNA mutants on the transcription products from cloned ribosomal protein genes of yeast

1981 • 206 citations

U1, U2, and U4/U6 small nuclear ribonucleoproteins are required for in vitro splicing but not polyadenylation

1986 • 192 citations

Spliceosome assembly involves the binding and release of U4 small nuclear ribonucleoprotein.

1988 • 188 citations

Gel electrophoretic isolation of splicing complexes containing U1 small nuclear ribonucleoprotein particles.

1988 • 183 citations

Antisense probing of the human U4U6 snRNP with biotinylated 2′-OMe RNA oligonucleotides

1989 • 169 citations

The yeast RNA gene products are essential for mRNA splicing in vitro

1986 • 138 citations

Splicing of yeast nuclear pre-mRNA in vitro requires a functional 40S spliceosome and several extrinsic factors.

1987 • 137 citations

In vitro assembly of yeast U6 snRNP: a functional assay.

1989 • 134 citations

PRP4: a protein of the yeast U4/U6 small nuclear ribonucleoprotein particle.

1989 • 131 citations

Purification and visualization of native spliceosomes

1988 • 121 citations

An essential snRNA from S. cerevisiae has properties predicted for U4, including interaction with a U6-like snRNA

1987 • 104 citations

PRP4 (RNA4) from Saccharomyces cerevisiae: Its Gene Product Is Associated with the U4/U6 Small Nuclear Ribonucleoprotein Particle

1989 • 98 citations

Splicing a spliceosomal RNA

1989 • 95 citations

Domains of yeast U4 spliceosomal RNA required for PRP4 protein binding, snRNP-snRNP interactions, and pre-mRNA splicing in vivo.

1990 • 95 citations

Identification of a functional mammalian spliceosome containing unspliced pre-mRNA.

1988 • 75 citations

Fractionation and characterization of a yeast mRNA splicing extract.

1986 • 73 citations

PRP4: a Protein of the Yeast U4/U6 Small Nuclear Ribonucleoprotein Particle

1989 • 62 citations

PRP4 (RNA4) from Saccharomyces cerevisiae: its gene product is associated with the U4/U6 small nuclear ribonucleoprotein particle.

1989 • 53 citations

The PRP4 (RNA4) protein of Saccharomyces cerevisiae is associated with the 5' portion of the U4 small nuclear RNA.

1990 • 51 citations

Identification and nuclear localization of yeast pre-messenger RNA processing components: RNA2 and RNA3 proteins.

1986 • 33 citations

Pre-mRNA splicing in yeast

1991 • 30 citations