The Murine Antitumor Immune Response and Its Therapeutic Manipulation

An endotoxin-induced serum factor that causes necrosis of tumors.

1975 • 4,522 citations

Biology of the Mouse Histocompatibility-2 Complex

1975 • 1,145 citations

Natural Cell-Mediated Immunity

1978 • 1,063 citations

Antigenic properties of methylcholanthrene-induced tumors in mice of the strain of origin.

1953 • 686 citations

Cyclophosphamide-facilitated adoptive immunotherapy of an established tumor depends on elimination of tumor-induced suppressor T cells.

1982 • 640 citations

ANTIGENIC PROPERTIES OF CHEMICALLY INDUCED TUMORS*

1962 • 528 citations

Immunology of Experimental Tumors

1964 • 487 citations

Antigenicity of Murine Skin Tumors Induced by Ultraviolet Light2

1974 • 484 citations

A critique of the evidence for active host defence against cancer, based on personal studies of 27 murine tumours of spontaneous origin

1976 • 478 citations

Cellular Immunity Against Tumor Antigens

1969 • 474 citations

Ionizing Radiation and the Immune Response

1976 • 435 citations

T-cell-mediated suppression of anti-tumor immunity. An explanation for progressive growth of an immunogenic tumor.

1980 • 373 citations

Regualtion of the immune response to tumor antigens. I. Immunosuppressor cells in tumor-bearing hosts.

1976 • 339 citations

Cyclophosphamide-sensitive T lymphocytes suppress the in vivo generation of antigen-specific cytotoxic T lymphocytes

1977 • 337 citations

Tumor Antigens

1966 • 323 citations

ANTIGENIC MODULATION

1968 • 322 citations

Cell-Mediated Immunity to Tumor Cells

1974 • 268 citations

The in vitro generation and sustained culture of nude mouse cytolytic T-lymphocytes.

1979 • 268 citations

Passive Immunotherapy of Cancer in Animals and Man

1977 • 245 citations

"Anomalous" THY-1(+) killer cells in allogeneic and F1-anti-parental mixed leukocyte culture. Relation to natural killer cells and allospecific cytotoxic T lymphocytes

1982 • 237 citations

T-cell-derived helper factor allows in vivo induction of cytotoxic T cells in nu/nu mice

1980 • 228 citations

The in vivo distribution of autologous human and murine lymphoid cells grown in T cell growth factor (TCGF): implications for the adoptive immunotherapy of tumors.

1980 • 223 citations

Transplantation methods as a tool for detection of tumor-specific antigens.

1965 • 222 citations

Immunotherapy of Cancer: Present Status of Trials in Man

1977 • 212 citations

Cells mediating graft rejection in the mouse. I. Lyt-1 cells mediate skin graft rejection.

1981 • 211 citations

Regulation of the Immune Response to Tumor Antigens

1976 • 207 citations

Latency, histology, and antigenicity of tumors induced by ultraviolet light in three inbred mouse strains.

1977 • 202 citations

The roles of host and donor cells in the rejection of skin allografts by T cell‐deprived rats injected with syngeneic T cells

1982 • 190 citations

Transplantation Methods as a Tool for Detection of Tumor-specific Antigens*

2015 • 183 citations

Chemical Treatment of Tumors. V. Isolation of the Hemorrhage-Producing Fraction from <italic>Serratia marcescens (Bacillus prodigiosus)</italic> Culture Filtrate<xref ref-type="fn" rid="fn1"><sup>1</sup></xref>

1943 • 164 citations

Immunologic regulation of experimental cutaneous leishmaniasis. V. Characterization of effector and specific suppressor T cells.

1982 • 163 citations

Suppressor Cells: Permitters and Promoters of Malignancy?

1979 • 162 citations

Immunosuppression and the Role of Suppressive Factors in Cancer

1977 • 162 citations

Depression of macrophage function by a factor produced by neoplasms: a merchanism for abrogation of immune surveillance.

1976 • 158 citations

Abnormal migration of T lymphocyte clones.

1982 • 153 citations

Immunopotentiation with BCG. II. Modulation of the Response to Sheep Red Blood Cells2

1973 • 148 citations

Concomitant Tumor Immunity and the Resistance to a Second Tumor Challenge

1983 • 139 citations

THE MEDIATOR OF CELLULAR IMMUNITY

1971 • 136 citations

Chemical Treatment of Tumors. IX. Reactions of Mice with Primary Subcutaneous Tumors to Injection of a Hemorrhage-Producing Bacterial Polysaccharide<xref ref-type="fn" rid="fn1"><sup>1</sup></xref>

1944 • 133 citations

Similarities of the Anti-tumour Actions of Endotoxin, Lipid A and Double-stranded RNA

1973 • 127 citations

Expression of passively transferred immunity against an established tumor depends on generation of cytolytic T cells in recipient. Inhibition by suppressor T cells.

1983 • 123 citations

Reduction of syngeneic tumor growth by an anti-I-J-alloantiserum.

1977 • 120 citations

Regulation of specific cell-mediated cytotoxic response against SV40-induced tumor associated antigens by depletion of suppressor T cells with cyclophosphamide in mice.

1979 • 120 citations

In Vitro Induction of Cytotoxicity against Syngeneic Mastocytoma and Its Suppression by Spleen and Thymus Cells from Tumor-Bearing Mice

1976 • 118 citations

T cell-mediated immunosuppression as an obstacle to adoptive immunotherapy of the P815 mastocytoma and its metastases.

1981 • 118 citations

Regression and inhibition of sarcoma growth by interference with a radiosensitive T-cell population.

1978 • 118 citations

The immunological basis of endotoxin-induced tumor regression. Requirement for T-cell-mediated immunity.

1978 • 111 citations

CRITICAL REVIEW OF PREVIOUSLY REPORTED ANIMAL STUDIES OF TUMOR IMMUNOTHERAPY WITH NON‐SPECIFIC IMMUNOSTIMULANTS

1976 • 110 citations

Depression of Macrophage Function by a Factor Produced by Neoplasms: A Mechanism for Abrogation of Immune Surveillance

1976 • 109 citations

T-cell-mediated concomitant immunity to syngeneic tumors. I. Activated macrophages as the expressors of nonspecific immunity to unrelated tumors and bacterial parasites.

1977 • 101 citations

Inhibition of established transplants of chemically induced sarcomas in syngeneic mice by lymphocytes from immunized donors

1972 • 95 citations

The Macrophage In Neoplasia

2012 • 89 citations

Regulation of Immunity to the Azobenzenearsonate Hapten

1982 • 89 citations

Characterization of Suppressor Cells in Mice Bearing Syngeneic Mastocytoma

1977 • 87 citations

Generation and decay of the immune response to a progressive fibrosarcoma. II. Failure to demonstrate postexcision immunity after the onset of T cell-mediated suppression of immunity.

1984 • 86 citations

The immunological basis of endotoxin-induced tumor regression. Requirement for a pre-existing state of concomitant anti-tumor immunity.

1978 • 83 citations

Suppressor Cells in Tumor-Bearing Mice Capable of Nonspecific Blocking of in Vitro Immunization Against Transplant Antigens

1975 • 83 citations

The T lymphocyte antigen receptor—paradigm lost

1982 • 82 citations

Immunotherapy of cancer : present status of trials in man

1978 • 82 citations

Control of Experimental Contact Sensitivity

1980 • 82 citations

Bcg in Tumor Immunotherapy

1978 • 76 citations

Quantitation and clonal isolation of cytolytic T lymphocyte precursors selectively infiltrating murine sarcoma virus-induced tumors.

1981 • 72 citations

THE OCCURRENCE OF TWO TYPES OF CYTOTOXIC LYMPHOID CELLS IN MICE IMMUNISED WITH ALLOGENEIC TUMOUR CELLS

1970 • 70 citations

Separation of Populations of Sensitized Lymphoid Cells into Fractions Inhibiting and Fractions Enhancing Syngeneic Tumor Growth in Vivo

1976 • 66 citations

Immunotherapy of a chemically-induced sarcoma in rats: characterization of the effector T cell subset and nature of suppression.

1982 • 62 citations

THE THERAPEUTIC VALUE OF THE MIXED TOXINS OF THE STREPTOCOCCUS OF ERYSIPELAS AND BACILLUS PRODIGIOSUS IN THE TREATEMENT OF INOPER- ABLE MALIGNANT TUMORS

1896 • 61 citations

Mechanisms of Antitumor Action of Corynebacterium parvum : Nonspecific Tumor Cell Destruction at Site of an Immunologically Mediated Sensitivity Reaction to C. parvum 2

1975 • 60 citations

Mechanisms of anti-tumor action of Corynebacterium parvum. I. Potentiated tumor-specific immunity and its therapeutic limitations.

1981 • 60 citations

In vitro induction of tumour-specific immunity

1975 • 60 citations

Further Evidence for the Involvement of Thymus-Processed Lymphocytes in Syngeneic Tumor Cell Cytolysis

1973 • 60 citations

Tumor immunity to murine plasma cell tumors. II. Essential role of T lymphocytes in immune response

1973 • 59 citations

Enhancement of delayed hypersensitivity reaction with varieties of anti-cancer drugs. A common biological phenomenon.

1981 • 57 citations

Suppressor cell regulation of immune response to tumors: Abrogation by adult thymectomy

1977 • 54 citations

Contribution of host immunity to cyclophosphamide therapy of a chemically‐induced murine sarcoma

1973 • 51 citations

ADOPTIVE CHEMOIMMUNOTHERAPY OF CANCER IN ANIMALS: A REVIEW OF RESULTS, PRINCIPLES, AND PROBLEMS*

1976 • 51 citations

Detection of early and delayed antitumor effects following curative adoptive chemoimmunotherapy of established leukemia.

1980 • 49 citations

Human tumor-associated antigens identified by monoclonal antibodies

1982 • 47 citations

Mechanisms of anti-tumor action of Corynebacterium parvum. II. Potentiated cytolytic T cell response and its tumor-induced suppression.

1981 • 40 citations

In vitro induction of tumor-specific immunity. IV. Specific adoptive immunotherapy with cytotoxic T cells induced in vitro to plasmacytoma antigens

1977 • 38 citations

A critical examination of the foundations of immunotherapy for cancer

1979 • 37 citations

Macrophages elicited with heat-killed bacillus Calomette-Guérin protect C57BL/6J mice against a syngeneic melanoma.

1980 • 37 citations

Effectiveness of murine leukemia chemotherapy according to the immune state

1977 • 37 citations

Multiple effector roles of lymphocytes in allograft immunity

1973 • 31 citations

Abrogation of the in vitro generation of the cytotoxic T‐cell response to a murine tumor: The role of suppressor cells

1982 • 29 citations

Generation of cytolytic T lymphocytes in thymectomized, irradiated, and bone marrow-reconstituted mice.

1982 • 27 citations

Inhibition of tumor growth by monoclonal anti-I-J antibodies.

1983 • 26 citations

Modulation of antitumor immunity ? Immunobiologic approaches

1982 • 25 citations

The Mechanism of Graft Rejection and the Concept of Antigenic Strength

1981 • 25 citations

Analysis of synergy between cyclophosphamide Therapy and Immunity Against a Mouse Tumour

1978 • 25 citations

The case history of Mr T.I. Terminal patient or still curable?

1980 • 21 citations

Suppressor T cells activated in a primary in vitro response to non-major histocompatibility alloantigens.

1982 • 20 citations

In Vivo Antitumor Activity of Various Forms of Delayed-Type Hypersensitivity in Mice<xref ref-type="fn" rid="fn2">2</xref>

1979 • 20 citations

CELLS MEDIATING GRAFT REJECTION IN THE MOUSE

1982 • 18 citations

Manipulation of host resistance in cancer therapy

1982 • 13 citations

Nonspecific inhibition of tumor growth by allosensitized lymphocytes. I. Participation of polymorphonuclear leukocytes.

1978 • 12 citations

Arbeiten aus dem Königlichen Institut für Experimentelle Therapie zu Frankfurt a.M.

1906 • 6 citations

Action of Bacterial Toxins on Tumors. VI. Protection Against Tumor Hemorrhage Following Heterologous Immunization.

1943 • 4 citations

Nonspecific Inhibition of Tumor Growth by Allosensitized Lymphocytes

1978 • 4 citations

Milestones in tumor immunology.

1979 • 3 citations