Practice Guidelines in Acute Pancreatitis

A Clinically Based Classification System for Acute Pancreatitis

1993 • 2,752 citations

Endoscopic sphincterotomy complications and their management: an attempt at consensus

1991 • 2,712 citations

Hepatogastroenterology

2011 • 2,496 citations

Complications of Endoscopic Biliary Sphincterotomy

1996 • 2,443 citations

Systematic review of the long-term effects and economic consequences of treatments for obesity and implications for health improvement

2004 • 1,031 citations

CONTROLLED TRIAL OF URGENT ENDOSCOPIC RETROGRADE CHOLANGIOPANCREATOGRAPHY AND ENDOSCOPIC SPHINCTEROTOMY VERSUS CONSERVATIVE TREATMENT FOR ACUTE PANCREATITIS DUE TO GALLSTONES

1988 • 875 citations

Complications of Diagnostic and Therapeutic Ercp: A Prospective Multicenter Study

2001 • 875 citations

Acute Pancreatitis: Assessment of Severity with Clinical and CT Evaluation

2002 • 827 citations

Acute Necrotizing Pancreatitis: Treatment Strategy According to the Status of Infection

2000 • 812 citations

Early Treatment of Acute Biliary Pancreatitis by Endoscopic Papillotomy

1993 • 790 citations

IAP Guidelines for the Surgical Management of Acute Pancreatitis

2002 • 750 citations

Compared with parenteral nutrition, enteral feeding attenuates the acute phase response and improves disease severity in acute pancreatitis

1998 • 692 citations

Persistent organ failure during the first week as a marker of fatal outcome in acute pancreatitis

2004 • 616 citations

Early ERCP and Papillotomy Compared with Conservative Treatment for Acute Biliary Pancreatitis

1997 • 613 citations

Risk factors for complications after performance of ERCP

2002 • 577 citations

Enteral nutrition is superior to parenteral nutrition in severe acute pancreatitis: Results of a randomized prospective trial

1997 • 566 citations

Dynamic nature of early organ dysfunction determines outcome in acute pancreatitis

2002 • 539 citations

Early versus late necrosectomy in severe necrotizing pancreatitis

1997 • 539 citations

Pathophysiology of acute pancreatitis

2005 • 513 citations

Imaging and intervention in acute pancreatitis.

1994 • 507 citations

A randomized multicenter clinical trial of antibiotic prophylaxis of septic complications in acute necrotizing pancreatitis with imipenem.

1993 • 504 citations

Prophylactic antibiotic treatment in patients with predicted severe acute pancreatitis: a placebo-controlled, double-blind trial1 ☆

2004 • 500 citations

Early antibiotic treatment in acute necrotising pancreatitis

1995 • 498 citations

Prediction of outcome in acute pancreatitis: A comparative study of APACHE II, clinical assessment and multiple factor scoring systems

1990 • 483 citations

Percutaneous CT-guided catheter drainage of infected acute necrotizing pancreatitis: techniques and results.

1998 • 477 citations

Randomized clinical trial of specific lactobacillus and fibre supplement to early enteral nutrition in patients with acute pancreatitis

2002 • 470 citations

Outcome differences after endoscopic drainage of pancreatic necrosis, acute pancreatic pseudocysts, and chronic pancreatic pseudocysts

2002 • 469 citations

Meta-analysis of parenteral nutrition versus enteral nutrition in patients with acute pancreatitis

2004 • 467 citations

Controlled Clinical Trial of Selective Decontamination for the Treatment of Severe Acute Pancreatitis

1995 • 459 citations

Diagnosis, objective assessment of severity, and management of acute pancreatitis

1999 • 453 citations

Prevention of post-ERCP pancreatitis: a comprehensive review

2004 • 452 citations

Comparison of the Safety of Early Enteral vs Parenteral Nutrition in Mild Acute Pancreatitis

1997 • 446 citations

Guidelines for the management of acute pancreatitis

2002 • 441 citations

Magnetic Resonance Cholangiopancreatography

2003 • 423 citations

A Randomized Study of Early Nasogastric versus Nasojejunal Feeding in Severe Acute Pancreatitis

2005 • 422 citations

A prospective longitudinal study of observation versus surgical intervention in the management of necrotizing pancreatitis

1991 • 416 citations

A Modified CT Severity Index for Evaluating Acute Pancreatitis: Improved Correlation with Patient Outcome

2004 • 409 citations

Antibiotic therapy for prophylaxis against infection of pancreatic necrosis in acute pancreatitis

2010 • 405 citations

Percutaneous Necrosectomy and Sinus Tract Endoscopy in the Management of Infected Pancreatic Necrosis: An Initial Experience

2000 • 404 citations

Etiological and prognostic factors in human acute pancreatitis: a review.

1982 • 401 citations

Management of acute pancreatitis: from surgery to interventional intensive care

2005 • 394 citations

Early diagnosis of pancreatic infection by computed tomography-guided aspiration

1987 • 387 citations

Enteral versus parenteral nutrition for acute pancreatitis

2010 • 380 citations

The natural history of pancreatic pseudocysts documented by computed tomography

1990 • 363 citations

Late mortality in patients with severe acute pancreatitis

2001 • 352 citations

Débridement and Closed Packing for the Treatment of Necrotizing Pancreatitis

1998 • 349 citations

Management of the critically ill patient with severe acute pancreatitis

2004 • 348 citations

Computed tomography and magnetic resonance imaging in the assessment of acute pancreatitis

2004 • 333 citations

Bacterial infection and extent of necrosis are determinants of organ failure in patients with acute necrotizing pancreatitis

1999 • 328 citations

Wait-and-see policy or laparoscopic cholecystectomy after endoscopic sphincterotomy for bile-duct stones: a randomised trial

2002 • 327 citations

Severe Acute Pancreatitis

2004 • 317 citations

Early and late complications after pancreatic necrosectomy

2005 • 307 citations

Hemoconcentration Is an Early Marker for Organ Failure and Necrotizing Pancreatitis

2000 • 303 citations

Factors influencing morbidity and mortality in acute pancreatitis; an analysis of 279 cases.

1995 • 300 citations

Prospective controlled study of endoscopic ultrasonography and endoscopic retrograde cholangiography in patients with suspected common-bileduct lithiasis

1996 • 299 citations

Acute Pancreatitis in Five European Countries: Etiology and Mortality

2002 • 297 citations

Human pancreatic tissue concentration of bactericidal antibiotics

1992 • 293 citations

Hypocaloric jejunal feeding is better than total parenteral nutrition in acute pancreatitis: results of a randomized comparative study

2002 • 291 citations

Selected management of pancreatic pseudocysts: operative versus expectant management.

1992 • 288 citations

Factors Predicting Mortality in Severe Acute Pancreatitis

2003 • 272 citations

Pancreatic stent placement for duct disruption

2002 • 260 citations

Diclofenac reduces the incidence of acute pancreatitis after endoscopic retrograde cholangiopancreatography

2003 • 259 citations

A randomised clinical trial to assess the effect of total enteral and total parenteral nutritional support on metabolic, inflammatory and oxidative markers in patients with predicted severe acute pancreatitis (APACHEE II ≥ 6)

2003 • 256 citations

Predicting gallstone pancreatitis with laboratory parameters: a meta-analysis.

1994 • 254 citations

Predictors of outcome in pancreatic duct disruption managed by endoscopic transpapillary stent placement

2005 • 252 citations

Aggressive Endoscopic Therapy for Pancreatic Necrosis and Pancreatic Abscess: A New Safe and Effective Treatment Algorithm (videos)

2006 • 250 citations

National Institutes of Health State-of-the-Science Conference Statement: ERCP for diagnosis and therapy, January 14-16, 2002

2002 • 245 citations

Early and late complications after endoscopic sphincterotomy for biliary lithiasis with and without the gall bladder 'in situ'.

1984 • 242 citations

Diagnosis of choledocholithiasis by endoscopic ultrasonography

1994 • 235 citations

Gabexate mesilate in human acute pancreatitis

1993 • 231 citations

Necrotizing Pancreatitis

2001 • 230 citations

Can endoscopic ultrasound or magnetic resonance cholangiopancreatography replace ERCP in patients with suspected biliary disease? A prospective trial and cost analysis

2001 • 219 citations

Role of ultrasonographically guided fine-needle aspiration cytology in the diagnosis of infected pancreatic necrosis

1998 • 218 citations

Early Severe Acute Pancreatitis: Characteristics of a New Subgroup

2001 • 218 citations

Potentially Fatal Bleeding in Acute Pancreatitis: Pathophysiology, Prevention, and Treatment

2003 • 217 citations

Endoscopic ultrasonography versus cholangiography for the diagnosis of choledocholithiasis

1998 • 217 citations

NF-κB activation in pancreas induces pancreatic and systemic inflammatory response

2002 • 216 citations

Diagnosis of choledocholithiasis: EUS or magnetic resonance cholangiography? A prospective controlled study

1999 • 215 citations

Multiple organ dysfunction associated with severe acute pancreatitis*

2002 • 212 citations

Endoscopic ultrasonography for diagnosing choledocholithiasis: a prospective comparative study with ultrasonography and computed tomography

1997 • 211 citations

Controlled clinical trial of pefloxacin versus imipenem in severe acute pancreatitis

1998 • 209 citations

Early treatment with antibiotics reduces the need for surgery in acute necrotizing pancreatitis—a single-center randomized study

2001 • 208 citations

Use of magnetic resonance cholangiography in the diagnosis of choledocholithiasis: prospective comparison with a reference imaging method

1999 • 208 citations

Prospective assessment of the utility of EUS in the evaluation of gallstone pancreatitis

1999 • 207 citations

Prophylactic Antibiotic Administration Reduces Sepsis and Mortality in Acute Necrotizing Pancreatitis: A Meta-Analysis

2001 • 206 citations

A randomised, double blind, multicentre trial of octreotide in moderate to severe acute pancreatitis

1999 • 203 citations

The diagnostic accuracy of magnetic resonance cholangiopancreatography and ultrasound compared with direct cholangiography in the detection of choledocholithiasis

1999 • 199 citations

A technique for laparoscopic-assisted percutaneous drainage of infected pancreatic necrosis and pancreatic abscess

2001 • 196 citations

Metaanalysis of Randomized Controlled Trials of Endoscopic Retrograde Cholangiography and Endoscopic Sphincterotomy for The Treatment of Acute Biliary Pancreatitis

1999 • 195 citations

Pancreatic Infection in Severe Pancreatitis

2001 • 189 citations

Is Severity of Necrotizing Pancreatitis Increased in Extended Necrosis and Infected Necrosis?

2002 • 189 citations

Association of extent and infection of pancreatic necrosis with organ failure and death in acute necrotizing pancreatitis

2005 • 186 citations

Reduction in Mortality With Delayed Surgical Therapy of Severe Pancreatitis

2002 • 185 citations

Does an Infected Peripancreatic Fluid Collection or Abscess Mandate Operation?

2000 • 185 citations

Comparison of Endoscopic Retrograde Cholangiopancreatography with MR Cholangiopancreatography in Patients with Pancreatitis

1999 • 179 citations

Severe Acute Pancreatitis: Nonsurgical Treatment of Infected Necroses

2005 • 179 citations

Minimally Invasive Retroperitoneal Pancreatic Necrosectomy

2003 • 177 citations

Prognostic factors in sterile pancreatic necrosis

1992 • 174 citations

Can fluid resuscitation prevent pancreatic necrosis in severe acute pancreatitis?

2002 • 172 citations

CT-guided aspiration of suspected pancreatic infection

1995 • 172 citations

Role of the Gut in the Course of Severe Acute Pancreatitis

2003 • 169 citations

Fatal Outcome in Acute Pancreatitis: Its Occurrence and Early Prediction

2001 • 168 citations

Intestinal Hypoperfusion Contributes to Gut Barrier Failure in Severe Acute Pancreatitis

2003 • 158 citations

Hemoconcentration: an early marker of severe and/or necrotizing pancreatitis? a critical appraisal

2001 • 155 citations

Endoscopic retrograde cholangiopancreatography in gallstone-associated acute pancreatitis

2004 • 155 citations

Detection of choledocholithiasis by EUS in acute pancreatitis: A prospective evaluation in 100 consecutive patients

2001 • 154 citations

Percutaneous Drainage of Pancreatic Pseudocysts Is Associated With a Higher Failure Rate Than Surgical Treatment in Unselected Patients

1999 • 153 citations

Hemoconcentration: an early marker of severe and/or necrotizing pancreatitis? a critical appraisal

2001 • 153 citations

Fungal Infections in Patients with Severe Acute Pancreatitis and the Use of Prophylactic Therapy

2003 • 152 citations

Management of severe acute pancreatitis

2003 • 151 citations

Severe Acute Pancreatitis: Prognostic Factors in 270 Consecutive Patients

2000 • 149 citations

Hemorrhagic complications of pancreatitis: Radiologic evaluation with emphasis on CT imaging

2001 • 148 citations

Is obesity a risk factor in acute pancreatitis? A meta-analysis

2004 • 147 citations

Combination of APACHE-II score and an obesity score (APACHE-O) for the prediction of severe acute pancreatitis

2004 • 146 citations

Ulinastatin for pancreatitis after endoscopic retrograde cholangiopancreatography: A randomized, controlled trial

2005 • 144 citations

Oxidative stress in acute pancreatitis.

1999 • 143 citations

Treatment with bindarit, a blocker of MCP-1 synthesis, protects mice against acute pancreatitis

2005 • 142 citations

Inflammatory cytokines, C reactive protein, and procalcitonin as early predictors of necrosis infection in acute necrotizing pancreatitis

2003 • 142 citations

EUS for suspected choledocholithiasis: Do benefits outweigh costs? A prospective, controlled study

2003 • 142 citations

Prospective placebo-controlled randomized trial of lexipafant in predicted severe acute pancreatitis

1997 • 139 citations

Risk factors for complications after performance of ERCP

2002 • 139 citations

Preoperative Versus Postoperative Endoscopic Retrograde Cholangiopancreatography in Mild to Moderate Gallstone Pancreatitis

2000 • 138 citations

Computed tomography severity index is a predictor of outcomes for severe pancreatitis

2000 • 137 citations

Percutaneous Catheter-directed Debridement of Infected Pancreatic Necrosis: Results in 20 Patients

1998 • 135 citations

Predicting the presence of choledocholithiasis in patients with symptomatic cholelithiasis.

1996 • 134 citations

Does Mortality Occur Early or Late in Acute Pancreatitis?

2000 • 133 citations

Characteristics of Infection with Candida Species inPatients with Necrotizing Pancreatitis

2002 • 131 citations

Useful Markers for Predicting Severity and Monitoring Progression of Acute Pancreatitis

2003 • 130 citations

Natural History of Necrotizing Pancreatitis

2003 • 129 citations

No Strict Correlation Between Necrosis and Organ Failure in Acute Pancreatitis

2000 • 125 citations

Serum lipase levels in nonpancreatic abdominal pain versus acute pancreatitis.

1993 • 124 citations

Surgical management of acute necrotizing pancreatitis: a 13-year experience and a systematic review

2003 • 124 citations

Physiological effects of enteral and parenteral feeding on pancreaticobiliary secretion in humans

2003 • 123 citations

Surgical Treatment for Severe Acute Pancreatitis: Extent and Surgical Control of Necrosis Determine Outcome

2002 • 122 citations

A pancreatic ductal leak should be sought to direct treatment in patients with acute pancreatitis

2001 • 121 citations

Obesity: A Risk Factor for Severe Acute Biliary and Alcoholic Pancreatitis

1998 • 119 citations

Fungal infection in acute necrotizing pancreatitis11No competing interests declared.

1999 • 115 citations

Signal transduction, calcium and acute pancreatitis

2003 • 115 citations

The Role of Magnetic Resonance Cholangiography in the Management of Patients With Gallstone Pancreatitis

2005 • 113 citations

Magnetic Resonance Cholangiopancreatography Accurately Detects Common Bile Duct Stones in Resolving Gallstone Pancreatitis

2005 • 111 citations

Nonsurgical Treatment of Acute Necrotizing Pancreatitis

1996 • 111 citations

Initial Management of Acute Pancreatitis: Critical Issues During the First 72 Hours

2004 • 111 citations

Acute Pancreatitis. Diagnosis and Therapy

1994 • 108 citations

Sphincter stencels and gallstone migration through the biliary tract

1993 • 108 citations

A systematic review and economic evaluation of magnetic resonance cholangiopancreatography compared with diagnostic endoscopic retrograde cholangiopancreatography

2004 • 108 citations

Prediction of Common Bile Duct Stones Prior to Cholecystectomy

1998 • 108 citations

Intra-abdominal Candida infection during acute necrotizing pancreatitis has a high prevalence and is associated with increased mortality

1998 • 107 citations

Risk of death from acute pancreatitis

1996 • 106 citations

Incidence and Reversibility of Organ Failure in the Course of Sterile or Infected Necrotizing Pancreatitis

2001 • 106 citations

Endoscopic therapy of complete and partial pancreatic duct disruptions.

1998 • 106 citations

Prophylaxis of ERCP-related pancreatitis: A randomized, controlled trial of somatostatin and gabexate mesylate1 1The trial was designed and the manuscript was written by Dr. Andriulli. No pharmaceutical or private grants were searched for or made available for performing the present work.

2004 • 106 citations

Impact of microcirculatory flow pattern changes on the development of acute edematous and necrotizing pancreatitis in rabbit pancreas

1994 • 104 citations

Serum amyloid A is a better early predictor of severity than C-reactive protein in acute pancreatitis

2002 • 103 citations

Pancreatic ischemia associated with vasospasm in the early phase of human acute necrotizing pancreatitis.

2005 • 103 citations

MRI of Pancreatitis and Its Complications: Part 1, Acute Pancreatitis

2004 • 102 citations

The timing of biliary tract operations in patients with pancreatitis associated with gallstones.

1975 • 100 citations

Kupffer Cell Blockade Reduces Hepatic and Systemic Cytokine Levels and Lung Injury in Hemorrhagic Pancreatitis in Rats

2000 • 100 citations

Discriminant power and information content of Ranson's prognostic signs in acute pancreatitis: A meta-analytic study

1999 • 100 citations

Obesity: a prognostic factor of severity in acute pancreatitis.

1999 • 99 citations

Pancreatic Necrosectomy: Definitions and Technique

2005 • 97 citations

Serum creatinine and chest radiographs in the early assessment of acute pancreatitis

1999 • 96 citations

From acinar cell damage to systemic inflammatory response: Current concepts in pancreatitis

2001 • 96 citations

Comparison of Ranson, APACHE II and APACHE III Scoring Systems in Acute Pancreatitis

2002 • 93 citations

Outcome of severe acute pancreatitis

2005 • 93 citations

Pseudocyst drainage predisposes to infection when pancreatic necrosis is unrecognized.

1994 • 91 citations

Bile duct stones and laparoscopic cholecystectomy: a decision analysis to assess the roles of intraoperative cholangiography, EUS, and ERCP

1999 • 90 citations

Surgical management of severe pancreatitis including sterile necrosis.

2002 • 89 citations

Endoscopic sphincterotomy without cholecystectomy for gall stone pancreatitis.

1995 • 89 citations

Clinical characteristics and management of patients with early acute severe pancreatitis: Experience from a medical center in China

2004 • 89 citations

Assessment of severity in acute pancreatitis.

1991 • 88 citations

Endoscopic sphincterotomy for biliary pancreatitis: An alternative to cholecystectomy in high-risk patients

1994 • 88 citations

Acute pancreatitis: does gender matter?

2001 • 88 citations

The long-term fate of the gallbladder after endoscopic sphincterotomy

1987 • 87 citations

Evaluation of the Clinical Usefulness of APACHE II and SAPS Systems in the Initial Prognostic Classification of Acute Pancreatitis

1993 • 86 citations

Conservative management of infected necrosis complicating severe acute pancreatitis

2003 • 86 citations

Association of antioxidant enzyme gene polymorphisms and glutathione status with severe acute pancreatitis

2004 • 86 citations

Helical computed tomographic cholangiography versus endosonography for suspected bile duct stones: a prospective blinded study in non-jaundiced patients

1999 • 86 citations

Natural History of Organ Failure in Acute Pancreatitis

2003 • 86 citations

Prospective comparison of endoscopic ultrasonography and endoscopic retrograde cholangiopancreatography in the detection of bile duct stones

1997 • 85 citations

Is the Monocyte Chemotactic Protein-1 −2518 G Allele a Risk Factor for Severe Acute Pancreatitis?

2005 • 85 citations

Endoscopic Ultrasound-Guided Drainage of Pancreatic Pseudocysts Complicated by Portal Hypertension or by Intervening Vessels

2005 • 85 citations

Risks of leaving the gallbladder in situ after endoscopic sphincterotomy for bile duct stones

1991 • 84 citations

Diagnostic criteria in predicting a biliary origin of acute pancreatitis in the era of endoscopic ultrasound: Multicentre prospective evaluation of 213 patients

2005 • 82 citations

An endoscopic retrograde cholangiopancreatography (ERCP)-based algorithm for the management of pancreatic pseudocysts

1992 • 82 citations

Predicting fatal outcome in the early phase of severe acute pancreatitis by using novel prognostic models

2003 • 82 citations

Influence of Contrast-enhanced Computed Tomography on Course and Outcome in Patients with Acute Pancreatitis

2002 • 82 citations

Procaine Hydrochloride Fails to Relieve Pain in Patients with Acute Pancreatitis

2004 • 80 citations

The APACHE II Score Is Unreliable to Diagnose Necrotizing Pancreatitis on Admission to Hospital

2002 • 79 citations

Isovolemic Hemodilution with Dextran 60 as Treatment of Pancreatic Ischemia in Acute Pancreatitis Clinical Practicability of an Experimental Concept

1993 • 79 citations

CANDIDA INFECTION OF LOCAL NECROSIS IN SEVERE ACUTE PANCREATITIS IS ASSOCIATED WITH INCREASED MORTALITY

2000 • 78 citations

Obesity

1999 • 76 citations

New Approaches to Acute Pancreatitis: Role of Inflammatory Mediators

1999 • 76 citations

Where do ERCP, endoscopic ultrasound, magnetic resonance cholangiopancreatography, and intraoperative cholangiography fit in the management of acute biliary pancreatitis? A decision analysis model

2001 • 76 citations

Acute pancreatitis: medical and surgical management.

1994 • 75 citations

Laboratory Markers of Severe Acute Pancreatitis

2004 • 75 citations

Improved Prediction of Outcome in Patients With Severe Acute Pancreatitis by the APACHE II Score at 48 Hours After Hospital Admission Compared With the APACHE II Score at Admission

2002 • 74 citations

Comparison of Two Dosing Regimens of Gabexate in The Prophylaxis of Post-Ercp Pancreatitis

2003 • 74 citations

Case reports: Online First

2000 • 74 citations

Android fat distribution as predictor of severity in acute pancreatitis

2002 • 73 citations

Which etiology causes the most severe acute pancreatitis?

1999 • 72 citations

Prophylactic Antibiotics Alter the Bacteriology of Infected Necrosis in Severe Acute Pancreatitis

2002 • 72 citations

Where do ERCP, endoscopic ultrasound, magnetic resonance cholangiopancreatography, and intraoperative cholangiography fit in the management of acute biliary pancreatitis? A decision analysis model

2001 • 72 citations

Pleural Effusion as a Predictor of Severity in Acute Pancreatitis

1997 • 71 citations

Acute biliary pancreatitis: The roles of endoscopic ultrasonography and endoscopic retrograde cholangiopancreatography

1998 • 69 citations

Efficacy of Continuous Regional Arterial Infusion of a Protease Inhibitor and Antibiotic for Severe Acute Pancreatitis in Patients Admitted to an Intensive Care Unit

2004 • 68 citations

CC-chemokine activation in acute pancreatitis: enhanced release of monocyte chemoattractant protein-1 in patients with local and systemic complications

2003 • 68 citations

Acute pancreatitis : diagnosis and therapy

1994 • 68 citations

Roux-en-Y internal drainage is the best surgical option to treat patients with disconnected duct syndrome after severe acute pancreatitis

2001 • 68 citations

Do Normal Findings at Biliary Endoscopic Ultrasonography Obviate the Need for Endoscopic Retrograde Cholangiography in Patients with Suspicion of Common Bile Duct Stone? A Prospective Follow-Up Study of 238 Patients

2003 • 68 citations

The Clinical Value of Procalcitonin in Early Assessment of Acute Pancreatitis

2005 • 66 citations

Diagnostic Strategies for Extrahepatic Cholestasis of Indefinite Origin: Endoscopic Ultrasonography or Retrograde Cholangiography? Results of a Prospective Study

1997 • 66 citations

The Role of Endoscopic Ultrasonography in Biliary Tract Disease: Obstructive Jaundice

1994 • 66 citations

Laparoscopic transgastric pancreatic necrosectomy for infected pancreatic necrosis

2003 • 66 citations

Serum amyloid A is a better early predictor of severity than C-reactive protein in acute pancreatitis

2002 • 65 citations

High-dose allopurinol for prevention of post-ERCP pancreatitis: a prospective randomized double-blind controlled trial

2005 • 64 citations

Indications for surgery in severe acute pancreatitis

1994 • 64 citations

Incremental dynamic boles computed tomography of acute pancreatitis

1993 • 63 citations

Differential Prognosis of Gram‐Negative Versus Gram‐Positive Infected and Sterile Pancreatic Necrosis: Results of a Randomized Trial in Patients with Severe Acute Pancreatitis Treated with Adjuvant Selective Decontamination

1997 • 63 citations

Outcome of Necrosectomy in Acute Pancreatitis: the Case for Continued Vigilance

2002 • 63 citations

Early Debridement for Necrotizing Pancreatitis: is It Worthwhile?1

2002 • 61 citations

Plasmapheresis in the management of acute severe hyperlipidemic pancreatitis: Report of 5 cases

2005 • 61 citations

Octreotide treatment in patients with severe acute pancreatitis.

2000 • 61 citations

Visualization of the Heterogeneous Internal Structure of So-called “Pancreatic Necrosis” by Magnetic Resonance Imaging in Acute Necrotizing Pancreatitis

2002 • 60 citations

Evaluation of operative cholangiography in 2043 patients undergoing laparoscopic cholecystectomy

2001 • 59 citations

Surgical Treatment of Severe Acute Pancreatitis: Timing of Operation is Crucial for Survival

2003 • 58 citations

Calcitonin Precursors: Early Markers of Gut Barrier Dysfunction in Patients With Acute Pancreatitis

2003 • 58 citations

Microcirculatory Function and Tissue Damage Is Improved After Therapeutic Injection of Bovine Hemoglobin in Severe Acute Rodent Pancreatitis

2005 • 58 citations

Predictors of Severity in Acute Pancreatitis

1991 • 57 citations

Do We Need a Computed Tomography Examination in All Patients with Acute Pancreatitis within 72 h after Admission to Hospital for the Detection of Pancreatic Necrosis?

2001 • 57 citations

Increasing age and APACHE II scores are the main determinants of outcome from pancreatic necrosectomy

2003 • 57 citations

Evolving concepts in the pathophysiology of acute pancreatitis

2003 • 56 citations

Early events in acute pancreatitis

2004 • 55 citations

Primary endoscopic papillotomy (EPT) in patients with stones in the common bile duct and the gallbladder in situ: A 5‐8‐year follow‐up study

1988 • 54 citations

Early Physiological Response to Intensive Care as a Clinically Relevant Approach to Predicting the Outcome in Severe Acute Pancreatitis

2004 • 53 citations

Contrast-Enhanced Dynamic Computed Tomography Does Not Aggravate the Clinical Severity of Patients With Severe Acute Pancreatitis

2000 • 53 citations

Serum Trypsinogen-2 in the Prediction of Outcome in Acute Necrotizing Pancreatitis

1996 • 52 citations

Fungal Infection but Not Type of Bacterial Infection Is Associated with a High Mortality in Primary and Secondary Infected Pancreatic Necrosis

2004 • 52 citations

Effect of endoscopic sphincterotomy and interval cholecystectomy on late outcome after gallstone pancreatitis

1998 • 52 citations

Intravenous n‐acetylcysteine, ascorbic acid and selenium‐based anti‐oxidant therapy in severe acute pancreatitis

2003 • 51 citations

A Comparison of Serum Trypsinogen-2 and Trypsin-2- α 1-Antitrypsin Complex With Lipase and Amylase in The Diagnosis and Assessment of Severity in The Early Phase of Acute Pancreatitis

2001 • 51 citations

Emergence of Antibiotic Resistance in Infected Pancreatic Necrosis

2004 • 50 citations

Laparoscopic Management of Severe Acute Pancreatitis

2003 • 50 citations

Severe Acute Pancreatitis: When to Be Concerned?

2003 • 47 citations

Operations upon the biliary tract in patients with acute pancreatitis: aims, indications and timing.

1984 • 47 citations

Management of Patients with Extended Pancreatic Necrosis

2001 • 46 citations

Alterations of the Tissue Inhibitor of Metalloproteinase-3 (TIMP3) Gene in Pancreatic Adenocarcinomas

2005 • 46 citations

Rapid Urinary Trypsinogen-2 Test Strip in the Diagnosis of Acute Pancreatitis

2005 • 45 citations

Has Blood Glucose Level Measured on Admission to Hospital in a Patient with Acute Pancreatitis Any Prognostic Value?

2001 • 45 citations

Hypocalcemia in Patients with Acute Pancreatitis: A Putative Role for Systemic Endotoxin Exposure

2003 • 45 citations

Urinary trypsinogen activation peptide as a marker of severe acute pancreatitis

2004 • 44 citations

Acute Pancreatitis

1999 • 44 citations

Laparoscopic intracorporeal ultrasound versus fluoroscopic intraoperative cholangiography

2001 • 44 citations

MRCP and ERCP in the diagnosis of common bile duct stones

2002 • 43 citations

Pancreatic proteases in serum induce leukocyte-endothelial adhesion and pancreatic microcirculatory failure

2005 • 43 citations

Do Pancreatic Duct Stents Cause or Prevent Pancreatic Sepsis?

2003 • 43 citations

Calcitonin precursors in the prediction of severity of acute pancreatitis on the day of admission

2003 • 43 citations

Evaluation of the pattern of liver tests and yield of cholangiography in symptomatic choledocholithiasis: a prospective study

1997 • 43 citations

Long-term follow-up of patients with necrotizing pancreatitis treated by percutaneous necrosectomy.

2003 • 42 citations

An annotated algorithm for the evaluation of choledocholithiasis

2001 • 42 citations

Bacteriologic Status of Necrotic Tissue in Necrotizing Pancreatitis

1990 • 42 citations

Laparoscopic Pancreatic Necrosectomy

2000 • 41 citations

Gastric colonisation, intestinal permeability and septic morbidity in acute pancreatitis

2002 • 41 citations

Benefit of continuous regional arterial infusion of protease inhibitor and antibiotic in the management of acute necrotizing pancreatitis

2001 • 41 citations

Management of pancreatic necrosis in severe acute pancreatitis

2005 • 41 citations

Isovolemic hemodilution with dextran prevents contrast medium induced impairment of pancreatic microcirculation in necrotizing pancreatitis of the rat

1995 • 39 citations

Outcome of Open Necrosectomy in Acute Pancreatitis

2003 • 37 citations

Baseline Hypoxemia as a Prognostic Marker for Pulmonary Complications and Outcome in Patients with Acute Pancreatitis

2004 • 37 citations

Evidence-based assessment of diagnostic modalities for common bile duct stones

2002 • 37 citations

Case reports: Online First

2002 • 37 citations

Prophylactic antibiotic use in severe acute pancreatitis: hemlock, help, or hype?

2004 • 37 citations

Bacterial Infection of Pancreatic Necrosis: Role of Bacterial Translocation, Impact of Antibiotic Treatment

2001 • 36 citations

Presence and Extent of Extrapancreatic Fluid Collections Are Indicators of Severe Acute Pancreatitis

1999 • 36 citations

The Dynamics of the Oxidant-Antioxidant Balance in the Early Phase of Human Acute Biliary Pancreatitis

2004 • 35 citations

Genetic determinants of mortality in acute necrotizing pancreatitis

1994 • 34 citations

Nutrition in the management of necrotizing pancreatitis

2003 • 33 citations

Evidence-based assessment: Patient, procedure, or operator factors associated with ERCP complications

2002 • 32 citations

Endosonography with linear array instead of endoscopic retrograde cholangiography as the diagnostic tool in patients with moderate suspicion of common bile duct stones

2003 • 31 citations

Efficacy of serum nitric oxide level estimation in assessing the severity of necrotizing pancreatitis

2003 • 29 citations

Pulmonary infiltrations

1996 • 28 citations

Effect of Fluid Resuscitation with and without Endothelin A Receptor Blockade on Hemoconcentration and Organ Function in Experimental Pancreatitis

2000 • 28 citations

Laparoscopic infracolic necrosectomy for infected pancreatic necrosis

2003 • 28 citations

Clinical Pancreatology for Practicing Gastroenterologists and Surgeons

2005 • 27 citations

Comparison of multiple-parameter prognostic systems in acute pancreatitis

1988 • 26 citations

Acute pancreatitis: molecular biology update

2003 • 23 citations

Evidence-based assessment of ERCP in the treatment of pancreatitis

2002 • 22 citations

Early sequential changes in serum markers of acute pancreatitis induced by endoscopic retrograde cholangiopancreatography

2005 • 22 citations

Limitations of Fluoroscopic Intraoperative Cholangiography in Cases Suggestive of Choledocholithiasis

2005 • 21 citations

Effect of failed computed tomography-guided and endoscopic drainage on pancreatic pseudocyst management.

1993 • 19 citations

Prevalence and Predictors of Severity as Defined by Atlanta Criteria Among Patients Presenting with Acute Pancreatitis

2003 • 19 citations

Guiding the Reluctant

2003 • 19 citations

Contrast-enhanced computed tomography in acute pancreatitis: does contrast medium worsen its course due to impaired microcirculation?

2005 • 17 citations

Nutrition in the management of necrotizing pancreatitis

2003 • 17 citations

Acute Pancreatitis: Threat of Fungal Infection

2001 • 13 citations

Compartmentalization of the Protease-antiprotease Balance in Early Severe Acute Pancreatitis

2005 • 10 citations

Acute Pancreatitis: Conservative Management

1994 • 9 citations

Acute biliary pancreatitis: The roles of endoscopic ultrasonography and endoscopic retrograde cholangiopancreatography

1998 • 8 citations

Evaluation of Sonography in the Diagnosis of Acute Pancreatitis

1987 • 7 citations