Pancreatic proteases in serum induce leukocyte-endothelial adhesion and pancreatic microcirculatory failure

Neutrophil Mac-1 and MEL-14 Adhesion Proteins Inversely Regulated by Chemotactic Factors

1989 • 1,135 citations

In Vivo Confocal Scanning Laser Microscopy of Human Skin: Melanin Provides Strong Contrast

1995 • 1,067 citations

In Vivo Confocal Scanning Laser Microscopy of Human Skin II: Advances in Instrumentation and Comparison With Histology11The authors have declared conflict of interest.

1999 • 829 citations

A Better Model of Acute Pancreatitis for Evaluating Therapy

1992 • 802 citations

A single-centre double-blind trial of Trasylol therapy in primary acute pancreatitis

1978 • 535 citations

Stimulated mobilization of monocyte Mac-1 and p150,95 adhesion proteins from an intracellular vesicular compartment to the cell surface.

1987 • 435 citations

Leukocyte-endothelial cell interactions: Molecular mechanisms and implications in gastrointestinal disease☆☆☆

1998 • 382 citations

Leukocyte adherence to venular endothelium during ischemia-reperfusion

1989 • 381 citations

Gabexate for the Prevention of Pancreatic Damage Related to Endoscopic Retrograde Cholangiopancreatography

1996 • 378 citations

Platelet-Endothelial Cell Interactions During Ischemia/Reperfusion: The Role of P-Selectin

1998 • 360 citations

New synthetic inhibitors of C1r̄, C1 esterase, thrombin, plasmin, kallikrein and trypsin

1981 • 299 citations

Platelet-Endothelial Cell Interactions During Ischemia/Reperfusion: The Role of P-Selectin

1998 • 296 citations

Pancreatic ischaemia in experimental acute pancreatitis: Mechanism, significance and therapy

1990 • 276 citations

Trypsinogen activation peptides assay in the early prediction of severity of acute pancreatitis

1990 • 268 citations

The role of intercellular adhesion molecule 1 and neutrophils in acute pancreatitis and pancreatitis-associated lung injury

1999 • 263 citations

Gabexate mesilate in human acute pancreatitis

1993 • 231 citations

Control of leukocyte rolling velocity in TNF-α–induced inflammation by LFA-1 and Mac-1

2002 • 205 citations

PMN-Elastase in Comparison with CRP, Antiproteases, and LDH as Indicators of Necrosis in Human Acute Pancreatitis

1991 • 201 citations

Matrix metalloproteinase-9 promotes neutrophil migration and alveolar capillary leakage in pancreatitis-associated lung injury in the rat

2002 • 180 citations

Gabexate or somatostatin administration before ERCP in patients at high risk for post-ERCP pancreatitis: A multicenter, placebo-controlled, randomized clinical trial

2002 • 177 citations

Continuous regional arterial infusion of protease inhibitor and antibiotics in acute necrotizing pancreatitis

1996 • 161 citations

Granulocyte elastase in assessment of severity of acute pancreatitis

1990 • 156 citations

Effects of CXC chemokines on neutrophil activation and sequestration in hepatic vasculature

2001 • 146 citations

The application of stereological principles to morphometry of the microcirculation in different tissues

1977 • 130 citations

Specific Therapy for Local and Systemic Complications of Acute Pancreatitis With Monoclonal Antibodies Against ICAM-1

1999 • 129 citations

Pancreatic microcirculatory changes in experimental pancreatitis of graded severity in the rat.

1994 • 128 citations

Clinical usefulness of polymorphonuclear elastase in predicting the severity of acute pancreatitis: Results of a multicentre study

1991 • 125 citations

A monoclonal anti-interleukin 8 antibody (WS-4) inhibits cytokine response and acute lung injury in experimental severe acute necrotising pancreatitis in rabbits

1998 • 119 citations

Impairment of pancreatic microcirculation correlates with the severity of acute experimental pancreatitis.

1994 • 116 citations

Role of leukocyte adhesion molecules in complement-induced lung injury.

1993 • 115 citations

Intravital Fluorescence Microscopy: Impact of Light-induced Phototoxicity on Adhesion of Fluorescently Labeled Leukocytes

1997 • 112 citations

The effects of neutrophil depletion on a completely noninvasive model of acute pancreatitis-associated lung injury

1998 • 111 citations

Effects of cell purification methods on CD11b and l-selectin expression as well as the adherence and activation of leucocytes

1995 • 108 citations

Impact of microcirculatory flow pattern changes on the development of acute edematous and necrotizing pancreatitis in rabbit pancreas

1994 • 104 citations

Pancreatic elastase activates pulmonary nuclear factor kappa B and inhibitory kappa B, mimicking pancreatitis-associated adult respiratory distress syndrome

2000 • 102 citations

Microcirculatory derangements in acute pancreatitis

2001 • 100 citations

Signaling Pathways Involved in IL-8-Dependent Activation of Adhesion Through Mac-1

2002 • 99 citations

Morphometric characteristics and homogeneity of a new model of acute pancreatitis in the rat

1992 • 98 citations

Ischemia reperfusion of the pancreas: A new in vivo model for acute pancreatitis in rats

1995 • 95 citations

Ischemia-reperfusion-induced pancreatic microvascular injury

1996 • 88 citations

Interstitial protease activation is the central event in progression to necrotizing pancreatitis.

1994 • 79 citations

Anti-Neutrophil Antibody Attenuates the Severity of Acute Lung Injury in Rats With Experimental Acute Pancreatitis

1995 • 76 citations

Gabexate mesilate vs aprotinin in human acute pancreatitis (GA.ME.P.A.)

1993 • 74 citations

IL-1 and TNF independent pathways mediate ICAM-1/VCAM-1 up-regulation in ischemia reperfusion injury

2001 • 72 citations

Pancreatic microcirculation in acute pancreatitis

1998 • 63 citations

Trypsin and activation of circulating trypsinogen contribute to pancreatitis-associated lung injury

1999 • 63 citations

Interstitial trypsinogen release and its relevance to the transformation of mild into necrotizing pancreatitis in rats

1999 • 62 citations

Technetium-99m-Labeled White Blood Cells

1998 • 61 citations

Blocking Pulmonary ICAM-1 Expression Ameliorates Lung Injury in Established Diet-Induced Pancreatitis

2001 • 59 citations

Hyperoncotic ultrahigh molecular weight dextran solutions reduce trypsinogen activation, prevent acinar necrosis, and lower mortality in rodent pancreatitis

1993 • 58 citations

Improvement of impaired pancreatic microcirculation by isovolemic hemodilution protects pancreatic morphology in acute biliary pancreatitis.

1993 • 52 citations

Up-regulation of lung vascular ICAM-1 in rats is complement dependent.

1995 • 52 citations

Early complement system activation and neutrophil priming in acute pancreatitis: Participation of trypsin

1997 • 49 citations

Regional effects of nafamostat, a novel potent protease and complement inhibitor, on severe necrotizing pancreatitis

2001 • 49 citations

Kinetic Studies on the Fragmentation of the Third Component of Complement (C3) by Trypsin

1977 • 46 citations

Does stress play a role in the development of severe pancreatitis in rats?

1990 • 45 citations

Hemorrhagic hypotension induces arteriolar vasomotion and intermittent capillary perfusion in rat pancreas

1994 • 44 citations

Characterization and prevention of phototoxic effects in intravital fluorescence microscopy in the hamster dorsal skinfold model

2000 • 44 citations

Elastase Mimics Pancreatitis-Induced Hepatic Injury via Inflammatory Mediators

2000 • 43 citations

Expression of the Adhesion Molecules Mac-1 and l-Selectin on Neutrophils in Acute Pancreatitis is Protease- and Complement-Dependent

2001 • 39 citations

Oxygen Radicals Promote ICAM-1 Expression and Microcirculatory Disturbances in Experimental Acute Pancreatitis

2003 • 35 citations

Serum elastase 1 in inflammatory pancreatic and gastrointestinal diseases and in renal insufficiency. A comparison with other serum pancreatic enzymes

1987 • 35 citations

Small-volume resuscitation restores hemorrhage-induced microcirculatory disorders in rat pancreas

1996 • 29 citations

LFA-1 (CD11a/CD 18) and ICAM-1 (CD54) Antibodies Attenuate Superoxide Anion Release from Polymorphonuclear Leukocytes in Rats with Experimental Acute Pancreatitis

1996 • 27 citations

In Vivo Documentation of an Arteriovenous Shunt in Rat Pancreatic Acinar Tissue

1996 • 24 citations

Phenotypic changes in neutrophil granulocytes of healthy donors after G-CSF administration.

1999 • 24 citations

Activation of the Complement Cascade by Trypsin

1991 • 22 citations

A Novel Diamino-Pyridine Derivative Prevents Excessive Leukocyte Infiltration in Aggravation of Acute Necrotizing Pancreatitis

1999 • 19 citations

Evaluation of Morphology and Microcirculation of the Pancreas by ex vivo and in vivo Reflectance Confocal Microscopy

2001 • 18 citations

Platelet-Activating Factor Antagonist (TCV-309) Attenuates the Priming Effects of Bronchoalveolar Macrophages in Cerulein-Induced Pancreatitis Rats

1999 • 16 citations

Altered expression of adhesion molecules (L‐selectin and Mac‐1) on granulocytes during storage

1994 • 15 citations

Evidence for the Involvement of Phosphatidylinositol 3-Kinase in fMLP-Stimulated Neutrophil Adhesion to ICAM-1-Transfected Cells

2001 • 13 citations

Intraoperative radiotherapy for pancreatic adenocarcinoma

1998 • 10 citations

Trypsinogen activation peptides (TAP) in peritoneal fluid as predictors of late histopathologic injury in necrotizing pancreatitis of the rat.

1999 • 10 citations

Pancreatic elastase activates pulmonary NF-kB and IKB mimicking pancreatitis-associated

2000 • 3 citations