Bacterial Infection of Pancreatic Necrosis: Role of Bacterial Translocation, Impact of Antibiotic Treatment

A Clinically Based Classification System for Acute Pancreatitis

1993 • 2,752 citations

Detection of Circulating Tumor Necrosis Factor after Endotoxin Administration

1988 • 1,711 citations

Bacterial contamination of pancreatic necrosis

1986 • 926 citations

Compared with parenteral nutrition, enteral feeding attenuates the acute phase response and improves disease severity in acute pancreatitis

1998 • 692 citations

Glutamine and the preservation of gut integrity

1993 • 675 citations

A randomized multicenter clinical trial of antibiotic prophylaxis of septic complications in acute necrotizing pancreatitis with imipenem.

1993 • 504 citations

Early antibiotic treatment in acute necrotising pancreatitis

1995 • 498 citations

Controlled Clinical Trial of Selective Decontamination for the Treatment of Severe Acute Pancreatitis

1995 • 459 citations

A prospective longitudinal study of observation versus surgical intervention in the management of necrotizing pancreatitis

1991 • 416 citations

Early diagnosis of pancreatic infection by computed tomography-guided aspiration

1987 • 387 citations

Relationship of necrosis to organ failure in severe acute pancreatitis

1997 • 354 citations

Bacterial infection and extent of necrosis are determinants of organ failure in patients with acute necrotizing pancreatitis

1999 • 328 citations

Factors influencing morbidity and mortality in acute pancreatitis; an analysis of 279 cases.

1995 • 300 citations

Human pancreatic tissue concentration of bactericidal antibiotics

1992 • 293 citations

Role of antibiotics in acute pancreatitis: a meta-analysis

1998 • 234 citations

A Prospective Study to Determine the Efficacy of Antibiotics in Acute Pancreatitis

1976 • 231 citations

Evaluation of prophylactic antibiotics in acute pancreatitis

1975 • 218 citations

Controlled clinical trial of pefloxacin versus imipenem in severe acute pancreatitis

1998 • 209 citations

Pancreatic infection complicating acute pancreatitis

1993 • 207 citations

Endotoxaemia and serum tumour necrosis factor as prognostic markers in severe acute pancreatitis.

1992 • 203 citations

Antibiotika bei nekrotisierender Pankreatitis: Ergebnisse einer kontrollierten Studie

2008 • 200 citations

Management of sterile necrosis in instances of severe acute pancreatitis.

1995 • 177 citations

Prognostic factors in sterile pancreatic necrosis

1992 • 174 citations

Management of necrotizing pancreatitis by repeated operative necrosectomy using a zipper technique

1998 • 168 citations

Surgical Management of Necrotizing Pancreatitis

1989 • 150 citations

Pathogenesis of pancreatic sepsis

1993 • 150 citations

Pancreatic abscess and infected pancreatic necrosis

1987 • 147 citations

Pancreatic Abscess and Infected Pancreatic Necrosis: Different Local Septic Complications in Acute Pancreatitis

1987 • 138 citations

The Use of Ampicillin in Acute Pancreatitis

1975 • 131 citations

Role of the Macrophage in the Translocation of Intestinal Bacteria

1987 • 125 citations

Pathogenesis and Prevention of Early Pancreatic Infection in Experimental Acute Necrotizing Pancreatitis

1995 • 123 citations

Antibiotics in acute pancreatitis

1989 • 117 citations

Intestinal Bacteria Translocate Into Experimental Intra-abdominal Abscesses

1986 • 115 citations

Antibiotic treatment improves survival in experimental acute necrotizing pancreatitis

1996 • 112 citations

Nonsurgical Treatment of Acute Necrotizing Pancreatitis

1996 • 111 citations

Intra-abdominal Candida infection during acute necrotizing pancreatitis has a high prevalence and is associated with increased mortality

1998 • 107 citations

Antibiotic prophylaxis in the initial management of severe acute pancreatitis

1998 • 105 citations

Routes of spread of pathogens into the pancreas in a feline model of acute pancreatitis.

1994 • 99 citations

Antibacterial Activity of the Pancreatic Fluid

1985 • 95 citations

Gut Origin Sepsis, Macrophage Function, and Oxygen Extraction Associated with Acute Pancreatitis in the Rat

1996 • 85 citations

Bacterial Translocation

1993 • 84 citations

Microbiological findings in severe pancreatitis

1989 • 72 citations

Alterations in intestinal motility and microflora in experimental acute pancreatitis

1996 • 71 citations

SURGICAL MANAGEMENT OF NECROTIZING PANCREATITIS

1999 • 70 citations

Changes in the Gastrointestinal Tract during Enteral or Parenteral Feeding

2009 • 66 citations

The penetration of antibiotics into human pancreas

1989 • 63 citations

Infection and acute pancreatitis

1994 • 63 citations

Clinical trials of selective decontamination of the digestive tract

1990 • 63 citations

Alterations in intestinal function in acute pancreatitis in an experimental model

1996 • 62 citations

Pancreatic abscess and other pus‐harboring collections related to pancreatitis: A review of 108 cases

1990 • 50 citations

Classification and treatment of local septic complications in acute pancreatitis

1995 • 47 citations

Increase in endotoxin-induced mucosal permeability is related to increased nitric oxide synthase activity using the Ussing chamber

1999 • 46 citations

The protective effect of a reduction in intestinal flora on mortality of acute haemorrhagic pancreatitis in the rat.

1987 • 45 citations

Survey of antibiotic prophylaxis in acute pancreatitis in the UK and Ireland

1999 • 43 citations

Effect of a Platelet-Activating Factor Antagonist on Pancreatitis-Associated Gut Barrier Dysfunction in Rats

1998 • 43 citations

Blood-pancreatic juice barrier to antibiotic excretion

1986 • 42 citations

Influence of levamisole on pancreatic infection in acute pancreatitis

1992 • 41 citations

Mechanisms of sepsis in acute pancreatitis in opossums

1995 • 40 citations

Role of bacterial infection in Diet-Induced acute pancreatitis in mice

1992 • 40 citations

Endotoxin and Antiendotoxin Antibodies in Patients with Acute Pancreatitis

2000 • 30 citations

Prevention of bacterial infection and sepsis in acute severe pancreatitis.

1992 • 29 citations

Activation of cellular immune response in acute pancreatitis.

1997 • 28 citations

Ampicillin Concentrations in Pancreatic Fluid Bile Obtained at Endoscopic Retrograde Cholangiopancreatography (ERCP)

1979 • 26 citations

Duodeno-pancreatic secretions enhance bactericidal activity of antimicrobial drugs

1984 • 25 citations

[Diagnosis and therapy of primary pancreatic abscess].

1995 • 11 citations

Failure of Local and Systemic Bacterial Clearance in Rats with Acute Pancreatitis

1995 • 11 citations

Selective decontamination in intensive care practice: A review of clinical experience

1990 • 11 citations

Bacterial Translocation in Acute Pancreatitis

1996 • 10 citations

Bacteremia in acute pancreatitis of different etiologies.

1995 • 8 citations

Antibiotics in acute pancreatitis: the debate revisited.

1995 • 6 citations