BMP and FGF regulate the development of EGF-responsive neural progenitor cells

Generation of Neurons and Astrocytes from Isolated Cells of the Adult Mammalian Central Nervous System

1992 • 5,296 citations

Subventricular Zone Astrocytes Are Neural Stem Cells in the Adult Mammalian Brain

1999 • 3,822 citations

Growth of a rat neuroblastoma cell line in serum-free supplemented medium.

1979 • 2,285 citations

Sonic hedgehog, a member of a family of putative signaling molecules, is implicated in the regulation of CNS polarity

1993 • 2,146 citations

The Spemann Organizer Signal noggin Binds and Inactivates Bone Morphogenetic Protein 4

1996 • 1,604 citations

A multipotent EGF-responsive striatal embryonic progenitor cell produces neurons and astrocytes

1992 • 1,514 citations

Promoter traps in embryonic stem cells: a genetic screen to identify and mutate developmental genes in mice.

1991 • 1,358 citations

Single factors direct the differentiation of stem cells from the fetal and adult central nervous system.

1996 • 1,164 citations

Isolation, Characterization, and use of Stem Cells from the CNS

1995 • 819 citations

Cleavage orientation and the asymmetric inheritance of notchl immunoreactivity in mammalian neurogenesis

1995 • 764 citations

Identification of type I receptors for osteogenic protein-1 and bone morphogenetic protein-4.

1994 • 737 citations

Bone morphogenetic proteins (BMPs) as regulators of dorsal forebrain development

1997 • 705 citations

Bone Morphogenetic Proteins Promote Astroglial Lineage Commitment by Mammalian Subventricular Zone Progenitor Cells

1996 • 681 citations

decapentaplegic Is Essential for the Maintenance and Division of Germline Stem Cells in the Drosophila Ovary

1998 • 648 citations

Antagonistic Interactions between FGF and BMP Signaling Pathways: A Mechanism for Positioning the Sites of Tooth Formation

1997 • 604 citations

A self-renewing multipotential stem cell in embryonic rat cerebral cortex

1994 • 578 citations

Cell lineage in the cerebral cortex of the mouse studied in vivo and in vitro with a Recombinant Retrovirus

1988 • 569 citations

Requirement for BMP Signaling in Interdigital Apoptosis and Scale Formation

1996 • 552 citations

Clonally Related Cortical Cells Show Several Migration Patterns

1988 • 510 citations

Distinct roles of type I bone morphogenetic protein receptors in the formation and differentiation of cartilage

1997 • 504 citations

Progression from Extrinsic to Intrinsic Signaling in Cell Fate Specification

1999 • 495 citations

Asymmetric Localization of a Mammalian Numb Homolog during Mouse Cortical Neurogenesis

1996 • 479 citations

Distinct roles for bFGF and NT-3 in the regulation of cortical neurogenesis

1995 • 476 citations

Clonal analysis of oligodendrocyte development in culture: Evidence for a developmental clock that counts cell divisions

1986 • 456 citations

FGF2 Concentration Regulates the Generation of Neurons and Glia from Multipotent Cortical Stem Cells

1997 • 455 citations

Signal relay by BMP antagonism controls the SHH/FGF4 feedback loop in vertebrate limb buds

1999 • 455 citations

Basic Fibroblast Growth Factor (Fgf2) Is Necessary for Cell Proliferation and Neurogenesis in the Developing Cerebral Cortex

2000 • 419 citations

Cloning and growth of multipotential neural precursors: Requirements for proliferation and differentiation

1993 • 381 citations

FGF-4 and BMP-2 have opposite effects on limb growth

1993 • 377 citations

Isolation of Lineage-Restricted Neuronal Precursors from Multipotent Neuroepithelial Stem Cells

1997 • 369 citations

Response Diversity and the Timing of Progenitor Cell Maturation Are Regulated by Developmental Changes in EGFR Expression in the Cortex

1997 • 329 citations

Fates of visual cortical neurons in the ferret after isochronic and heterochronic transplantation

1988 • 311 citations

Rod photoreceptor development in vitro: Intrinsic properties of proliferating neuroepithelial cells change as development proceeds in the rat retina

1990 • 299 citations

Fibroblast Growth Factor 2 (FGF-2) Promotes Acquisition of Epidermal Growth Factor (EGF) Responsiveness in Mouse Striatal Precursor Cells: Identification of Neural Precursors Responding to both EGF and FGF-2

1998 • 292 citations

Multiple Roles of Bone Morphogenetic Protein Signaling in the Regulation of Cortical Cell Number and Phenotype

1999 • 279 citations

Neuronal Differentiation of Precursors in the Neocortical Ventricular Zone Is Triggered by BMP

1998 • 277 citations

Changes in retinal cell fate induced by overexpression of EGF receptor

1995 • 248 citations

Intrinsic programs of patterned cell lineages in isolated vertebrate CNS ventricular zone cells

1998 • 243 citations

Cloned multipotential precursors from the mouse cerebrum require FGF-2, whereas glial restricted precursors are stimulated with either FGF-2 or EGF

1995 • 238 citations

BMPs negatively regulate structure and function of the limb apical ectodermal ridge

1999 • 232 citations

Morphogenesis of Digits in the Avian Limb Is Controlled by FGFs, TGFβs, and Noggin through BMP Signaling

1998 • 222 citations

Dpp receptor levels contribute to shaping the Dpp morphogen gradient in the Drosophila wing imaginal disc

1998 • 202 citations

BMPs mediate lateral inhibition at successive stages in feather tract development

1998 • 201 citations

Epidermal growth factor (EGF) stimulates EGF receptor synthesis.

1986 • 190 citations

Evidence for multiple precursor cell types in the embryonic rat cerebral cortex

1995 • 182 citations

Multipotential and lineage restricted precursors coexist in the mammalian perinatal subventricular zone

1997 • 170 citations

Multiple restricted lineages in the embryonic rat cerebral cortex

1993 • 166 citations

BMPs inhibit neurogenesis by a mechanism involving degradation of a transcription factor

1999 • 164 citations

Early divergence and changing proportions of neuronal and glial precursor cells in the primate cerebral ventricular zone

1983 • 163 citations

Development of Bone Morphogenetic Protein Receptors in the Nervous System and Possible Roles in Regulating trkC Expression

1998 • 162 citations

Prenatal ontogeny of the epidermal growth factor receptor and its ligand, transforming growth factor alpha, in the rat brain

1997 • 160 citations

A Retinal Axon Fascicle Uses Spitz, an EGF Receptor Ligand, to Construct a Synaptic Cartridge in the Brain of Drosophila

1998 • 127 citations

Retinoic acid normalizes the increased gene transcription rate of TGF–α and EGFR in head and neck cancer cell lines

1996 • 120 citations

Localization of bFGF and FGF‐receptor in the developing nervous system of the embryonic and newborn rat

1993 • 106 citations

[56] Lineage analysis using retrovirus vectors

1993 • 96 citations

The prenatal growth of the albino rat

1932 • 94 citations

Expression of the fibroblast growth factor family and their receptor family genes during mouse brain development

1996 • 93 citations

Temporal, differential and regional expression of mRNA for basic fibroblast growth factor in the developing and adult rat brain

1991 • 90 citations

Developmental changes in progenitor cell responsiveness to cytokines

1999 • 89 citations

Changes in Epidermal Growth Factor Receptor Expression and Competence to Generate Glia Regulate Timing and Choice of Differentiation in the Retina

1998 • 83 citations

Regulation of regional differences in the differentiation of cerebral cortical neurons by EGF family-matrix interactions

1995 • 78 citations

Rapid and Long Term Effects of Protein Kinase C on Receptor Tyrosine Kinase Phosphorylation and Degradation

1995 • 67 citations

Complementary Distribution of Collagen Type IV and the Epidermal Growth Factor Receptor in the Rat Embryonic Telencephalon

1996 • 48 citations

Antagonists Go out on a Limb

1999 • 48 citations

Induction of deep layer cortical neurons in vitro

1997 • 41 citations

The Development of the External Form of the Rat: With Observations on the Origin of the Extraembryonic Coelom and Foetal Membranes

2013 • 40 citations

Expression of BMP‐6, a TGF‐β related morphogenetic cytokine, in rat radial glial cells

1994 • 34 citations

Transcriptional Down-regulation of Epidermal Growth Factor Receptors by Nerve Growth Factor Treatment of PC12 Cells

1998 • 27 citations

Environmental Signals Influence Expression of a Cortical Areal Phenotypein VitroIndependent of Effects on Progenitor Cell Proliferation

1996 • 25 citations

Acute Regulation of the Epidermal Growth Factor Receptor in Response to Nerve Growth Factor

1991 • 14 citations