Human very long-chain acyl-CoA synthetase and two human homologs: initial characterization and relationship to fatty acid transport protein

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

1994 • 63,397 citations

A simple method for displaying the hydropathic character of a protein

1982 • 22,471 citations

The Metabolic and Molecular Bases of Inherited Disease

1995 • 12,086 citations

Identification of prokaryotic and eukaryotic signal peptides and prediction of their cleavage sites

1997 • 5,415 citations

Putative X-linked adrenoleukodystrophy gene shares unexpected homology with ABC transporters

1993 • 1,175 citations

A conserved tripeptide sorts proteins to peroxisomes.

1989 • 1,113 citations

Expression cloning and characterization of a novel adipocyte long chain fatty acid transport protein

1994 • 854 citations

ENZYMATIC SYNTHESIS OF THE COENZYME A DERIVATIVES OF LONG CHAIN FATTY ACIDS

1953 • 631 citations

X-linked adrenoleukodystrophy

2007 • 631 citations

Protein Import into Peroxisomes and Biogenesis of the Organelle

1993 • 411 citations

STUDIES ON FATTY ACID OXIDATION

1953 • 354 citations

Lignoceric acid is oxidized in the peroxisome: implications for the Zellweger cerebro-hepato-renal syndrome and adrenoleukodystrophy.

1984 • 344 citations

Novel fatty acid beta-oxidation enzymes in rat liver mitochondria. II. Purification and properties of enoyl-coenzyme A (CoA) hydratase/3-hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase trifunctional protein.

1992 • 337 citations

Disorders of peroxisome biogenesis

1995 • 289 citations

Novel fatty acid beta-oxidation enzymes in rat liver mitochondria. I. Purification and properties of very-long-chain acyl-coenzyme A dehydrogenase.

1992 • 245 citations

Peroxisomal lignoceroyl-CoA ligase deficiency in childhood adrenoleukodystrophy and adrenomyeloneuropathy.

1988 • 219 citations

Fatty acid activation

1997 • 210 citations

Ancestry of the 4-chlorobenzoate dehalogenase: analysis of amino acid sequence identities among families of acyl:adenyl ligases, enoyl-CoA hydratases/isomerases, and acyl-CoA thioesterases

1992 • 194 citations

Purification and Properties of Long‐Chain Acyl‐Coenzyme‐A Synthetase from Rat Liver

1979 • 187 citations

Direct demonstration that the deficient oxidation of very long chain fatty acids in X-linked adrenoleukodystrophy is due to an impaired ability of peroxisomes to activate very long chain fatty acids

1988 • 158 citations

Molecular Cloning of cDNA Encoding Rat Very Long-chain Acyl-CoA Synthetase

1996 • 154 citations

Studies of the Acetyl Coenzyme A Synthetase Reaction

1963 • 78 citations

Distinct long chain and very long chain fatty acyl CoA synthetases in rat liver peroxisomes and microsomes

1988 • 77 citations

Purification and Characteristics of a Butyryl Coenzyme A Synthetase from Bovine Heart Mitochondria

1965 • 68 citations

Human Long-Chain Acyl-CoA Synthetase: Structure and Chromosomal Location1

1992 • 59 citations

Purification and Properties of Rat Liver Peroxisomal Very-Long-Chain Acyl-CoA Synthetase

1996 • 59 citations

Studies of the Acetyl Coenzyme A Synthetase Reaction

1965 • 51 citations

A Novel Relative of the Very-Long-Chain Acyl-CoA Synthetase and Fatty Acid Transporter Protein Genes with a Distinct Expression Pattern

1998 • 46 citations

Molecular cloning of fatty acid-transport protein cDNA from rat

1997 • 39 citations

cDNA cloning and mRNA distribution of a mouse very long‐chain acyl‐CoA synthetase

1998 • 36 citations

Purification of peroxisomes and subcellular distribution of enzyme activities for activation and oxidation of very-long-chain fatty acids in rat brain

1993 • 21 citations

X-linked Adrenoleukodystrophy

1995 • 17 citations

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