FKLF, a Novel Krüppel-Like Factor That Activates Human Embryonic and Fetal β-Like Globin Genes

Molecular cloning: A laboratory manual

1990 • 85,659 citations

Rapid production of full-length cDNAs from rare transcripts: amplification using a single gene-specific oligonucleotide primer.

1988 • 4,669 citations

Current protocols in molecular biology

1988 • 4,543 citations

Transcriptional Regulation in Mammalian Cells by Sequence-Specific DNA Binding Proteins

1989 • 3,219 citations

Isolation of cDNA encoding transcription factor Sp1 and functional analysis of the DNA binding domain

1987 • 1,640 citations

Transcriptional activation by recruitment

1997 • 1,163 citations

Linkage of β-thalassaemia mutations and β-globin gene polymorphisms with DNA polymorphisms in human β-globin gene cluster

1982 • 937 citations

A Novel, Erythroid Cell-Specific Murine Transcription Factor that Binds to the CACCC Element and is Related to the Krüppel Family of Nuclear Proteins†

1993 • 703 citations

The Molecular Basis of Blood Diseases.

1987 • 648 citations

Identification and Characterization of a Gene Encoding a Gut-enriched Krüppel-like Factor Expressed during Growth Arrest

1996 • 647 citations

Lethal β-thalassaemia in mice lacking the erythroid CACCC-transcription factor EKLF

1995 • 620 citations

Cloning by recognition site screening of two novel GT box binding proteins: a family of Sp1 related genes

1992 • 577 citations

Defective haematopoiesis in fetal liver resulting from inactivation of the EKLF gene

1995 • 572 citations

Cloning of GT box-binding proteins: a novel Sp1 multigene family regulating T-cell receptor gene expression.

1992 • 533 citations

Transcription Factor Sp1 Is Essential for Early Embryonic Development but Dispensable for Cell Growth and Differentiation

1997 • 524 citations

Two regulatory proteins that bind to the basic transcription element (BTE), a GC box sequence in the promoter region of the rat P-4501A1 gene.

1992 • 354 citations

Transcription in yeast activated by a putative amphipathic α helix linked to a DNA binding unit

1987 • 324 citations

A Gene for a Novel Zinc-finger Protein Expressed in Differentiated Epithelial Cells and Transiently in Certain Mesenchymal Cells

1996 • 311 citations

Cis- and trans-acting elements involved in the regulation of the erythroid promoter of the human porphobilinogen deaminase gene.

1989 • 272 citations

Identification of a novel TGF-β-regulated gene encoding a putative zinc finger protein in human osteoblasts

1995 • 264 citations

Isolation of a Gene Encoding a Functional Zinc Finger Protein Homologous to Erythroid Krüppel-Like Factor: Identification of a New Multigene Family

1995 • 260 citations

Transcription Factors and Hematopoietic Development

1995 • 236 citations

Isolation and Characterization of the cDNA Encoding BKLF/TEF-2, a Major CACCC-Box-Binding Protein in Erythroid Cells and Selected Other Cells

1996 • 229 citations

Role of Erythroid Kruppel-like Factor in Human γ- to β-Globin Gene Switching

1995 • 212 citations

The role of EKLF in human beta-globin gene competition.

1996 • 210 citations

cDNA cloning and transcriptional properties of a novel GC box-binding protein, BTEB2

1993 • 203 citations

Sp1 and the subfamily of zinc finger proteins with guanine-rich binding sites.

1992 • 181 citations

Ligation-anchored PCR: a simple amplification technique with single-sided specificity.

1992 • 181 citations

Control of Globin Gene Transcription

1990 • 172 citations

Silencing of human fetal globin expression is impaired in the absence of the adult beta-globin gene activator protein EKLF.

1996 • 154 citations

Base substitution at position -88 in a beta-thalassemic globin gene. Further evidence for the role of distal promoter element ACACCC.

1984 • 152 citations

Mechanisms of transcriptional activation in vivo: two steps forward

1996 • 122 citations

Developmental regulation of human gamma-globin genes in transgenic mice.

1993 • 100 citations

The CACC box upstream of human embryonic epsilon globin gene binds Sp1 and is a functional promoter element in vitro and in vivo

1991 • 82 citations

Function of normal and mutated gamma-globin gene promoters in electroporated K562 erythroleukemia cells

1990 • 80 citations

A single promoter directs both housekeeping and erythroid preferential expression of the human ferrochelatase gene.

1994 • 78 citations

Discrimination Among Potential Activators of the β-Globin CACCC Element by Correlation of Binding and Transcriptional Properties

1993 • 74 citations

Erythroid-specific activity of the glycophorin B promoter requires GATA-1 mediated displacement of a repressor.

1992 • 71 citations

Transcriptional Regulation of the Human Erythroid 5-Aminolevulinate Synthase Gene

1997 • 71 citations

Thalassemia intermedia: moderate reduction of beta globin gene transcriptional activity by a novel mutation of the proximal CACCC promoter element

1991 • 63 citations

Thalassemia intermedia: moderate reduction of beta globin gene transcriptional activity by a novel mutation of the proximal CACCC promoter element

1991 • 54 citations

Interaction of Sp1 with the human gamma globin promoter: binding and transactivation of normal and mutant promoters

1991 • 50 citations

Nuclear protein factors and erythroid transcription of the human A_γ-globin gene

1989 • 49 citations

Identification and characterization of "zinc-finger" domains by the polymerase chain reaction.

1991 • 47 citations

Activation of β-Globin Promoter by Erythroid Krüppel-Like Factor

1998 • 44 citations

Interaction of Sp1 with the human gamma globin promoter: binding and transactivation of normal and mutant promoters

1991 • 42 citations

Globin Gene Switching

1996 • 41 citations

SpoU protein ofEscherichia colibelongs to a new family of putative rRNA methylases

1993 • 39 citations

Sequence of the human GATA-1 promoter

1992 • 21 citations

Functional profile of the human fetal gamma-globin gene upstream promoter region.

1992 • 9 citations