Effects of weekly administration of pegylated recombinant human OB protein on appetite profile and energy metabolism in obese men

Positional cloning of the mouse obese gene and its human homologue

1994 • 12,975 citations

Serum Immunoreactive-Leptin Concentrations in Normal-Weight and Obese Humans

1996 • 6,254 citations

The three-factor eating questionnaire to measure dietary restraint, disinhibition and hunger

1985 • 4,496 citations

Obesity as an independent risk factor for cardiovascular disease: a 26-year follow-up of participants in the Framingham Heart Study.

1983 • 4,204 citations

Effects of the obese Gene Product on Body Weight Regulation in ob / ob Mice

1995 • 4,057 citations

Congenital leptin deficiency is associated with severe early-onset obesity in humans

1997 • 2,900 citations

Increasing prevalence of overweight among US adults. The National Health and Nutrition Examination Surveys, 1960 to 1991

1994 • 2,623 citations

Body composition from fluid spaces and density: analysis of methods. 1961.

1993 • 2,554 citations

Effects of Recombinant Leptin Therapy in a Child with Congenital Leptin Deficiency

1999 • 1,959 citations

Techniques for Measuring Body Composition

1961 • 1,605 citations

Increasing Prevalence of Overweight Among US Adults

1994 • 1,479 citations

Recombinant Leptin for Weight Loss in Obese and Lean Adults

1999 • 1,408 citations

National Institutes of Health Consensus Development Conference Statement: Geriatric Assessment Methods for Clinical Decision‐making

1988 • 1,353 citations

Randomised placebo-controlled trial of orlistat for weight loss and prevention of weight regain in obese patients

1998 • 1,171 citations

Health implications of obesity

1991 • 833 citations

Undereating and underrecording of habitual food intake in obese men: selective underreporting of fat intake

2000 • 523 citations

The OB Protein (Leptin) Pathway - A Link Between Adipose Tissue Mass and Central Neural Networks

1996 • 517 citations

Health Implications of Obesity

1985 • 441 citations

Satiety related to 24 h diet-induced thermogenesis during high protein/carbohydrate vs high fat diets measured in a respiration chamber

1999 • 363 citations

CENTRAL OBESITY AND CORONARY HEART DISEASE IN MEN

1987 • 341 citations

The Maastricht Protocol for the Measurement of Body Composition and Energy Expenditure with Labeled Water

1995 • 322 citations

The therapeutic value of poly(ethylene glycol)-modified proteins

1991 • 280 citations

A dual-respiration chamber system with automated calibration

1997 • 256 citations

Weekly Subcutaneous Pegylated Recombinant Native Human Leptin (PEG-OB) Administration in Obese Men

2000 • 201 citations

The impact of obesity on health status: some implications for health care costs.

1995 • 166 citations

The appetizing effect of an apéritif in overweight and normal-weight humans

1999 • 160 citations

Chronic administration of OB protein decreases food intake by selectively reducing meal size in female rats

1998 • 157 citations

Determinants of weight maintenance in women after diet-induced weight reduction

1997 • 157 citations

Leptin selectively increases energy expenditure of food-restricted lean mice

1998 • 147 citations

The effect of exercise training on leptin levels in obese males

1998 • 143 citations

Mortality and Weight: Insured Lives and the American Cancer Society Studies

1985 • 137 citations

Chronic administration of OB protein decreases food intake by selectively reducing meal size in male rats

1998 • 75 citations

Regulation of Food Intake

2015 • 73 citations

Restrained eating, obesity, and cumulative food intake curves during four-course meals

1991 • 62 citations

The shape of the cumulative food intake curve in humans, during basic and manipulated meals

1990 • 56 citations

Costs and benefits when treating obesity.

1995 • 47 citations

Deceleration in cumulative food intake curves, changes in body temperature and diet-induced themogenesis

1990 • 46 citations

Diet-induced thermogenesis and cumulative food intake curves as a function of familiarity with food and dietary restraint in humans

1992 • 35 citations

A Comparison of Sibutramine and Dexfenfluramine in the Treatment of Obesity

1998 • 33 citations

Regulation of Food Intake

1972 • 6 citations